Results 81 to 90 of about 85,174 (277)

Infiltrating immune cells are increased in Palb2-KPC and Brca1-KPC tumors but not in Brca2-KPC.

, 2019
(A) Representative images of immunohistochemistry and immunofluorescence staining of CD3 and F4/80 in KPC, Brca1-KPC, Palb2-KPC and Brca2-KPC tumors. (B) Quantification of CD3 and F4/80 staining per field showed elevated CD3 positive T cells and F4/80 ...
Dongju Park (8190660), Raleigh Kladney (6991196), Thomas A. Mace (8190672), Christopher Koivisto (6991190), Matthias Szabolcs (8190666), Thomas Ludwig (220246), Reena Shakya (8190663), Jason R. Pitarresi (4452436), Ashley Hadjis (8190669)   +8 more
core   +1 more source

Phenotypic and Genetic Analysis of KPC-49, a KPC-2 Variant Conferring Resistance to Ceftazidime–Avibactam and Maintaining Resistance to Imipenem and Meropenem

Infection and Drug Resistance, 2023
Meng Yu, Qingzheng Wei, Weiqing Song, Jiangshui Yuan Clinical Laboratory, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, Shandong, People’s Republic of ChinaCorrespondence: Jiangshui Yuan; Weiqing Song, Clinical ...
Yu M, Wei Q, Song W, Yuan J
doaj  

Carbapenem resistance in gram-negative pathogens in an Iranian hospital: high prevalence of OXA-type carbapenemase genes [PDF]

Clinical and Experimental Pediatrics
Background The widespread dissemination of carbapenem-resistant gram-negative bacteria poses a significant threat to global public health. Purpose This study aimed to investigate the prevalence of carbapenem resistance in gram-negative bacteria isolated ...
Setareh Mamishi, Reihaneh Hosseinpour Sadeghi, Sadaf Sajedi Moghaddam, Babak Pourakbari, Shiva Poormohammadi, Maryam Sotoudeh Anvari, Shima Mahmoudi   +6 more
doaj   +1 more source

Diversity, virulence, and antimicrobial resistance of the KPC-producing Klebsiella pneumoniae ST307 clone

Microbial Genomics, 2017
The global spread of Klebsiella pneumoniae producing Klebsiella pneumoniae carbapenemase (KPC) has been mainly associated with the dissemination of high-risk clones. In the last decade, hospital outbreaks involving KPC-producing K.
L. Villa, C. Feudi, D. Fortini, S. Brisse, Virginie Passet, C. Bonura, A. Endimiani, C. Mammina, A. M. Ocampo, J. N. Jiménez, M. Doumith, N. Woodford, K. Hopkins, A. Carattoli   +13 more
semanticscholar   +1 more source

Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

Advanced Science, EarlyView.
Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang, Qin Wang, Zhuo Yao, Qing Wang, Yongtao Ji, Minqi Yang, Meng Wang, Shiyi Shao, Xinyu Zhao, Fu Zhang, Tingbo Liang, Qida Hu   +11 more
wiley   +1 more source

Production of Carbapenemases in Klebsiella pneumoniae Isolated in Saint-Petersburg [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2016
Carbapenem-resistant nosocomial K. pneumoniae isolates are a significant problem in clinical practice. Carbapenem resistance in K. pneumoniae isolated from hospitalized patients was 2.8% over the study period.
Barantsevich E.P., Barantsevich N.E., Shlyakhto E.V.   +2 more
doaj  

Oseltamivir drug‐disease modelling in infants with influenza virus infection

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Oseltamivir is a commonly used neuraminidase inhibitor for treatment of influenza infection, but little data exist regarding concentration‐response relationships. Methods Pharmacokinetic (PK) and viral dynamic data from an earlier NIAID Collaborative Antiviral Study Group trial in paediatric patients with influenza from 0–23 months of age
Kun Wang, David W. Kimberlin, Richard J. Whitley, Edward P. Acosta, For the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group   +4 more
wiley   +1 more source

Women Empowerment in India – A Perspective

National Journal of Community Medicine, 2018
Background: The study presents an index of women empower- ment based on a statistical technique of data reduction viz. factor analysis and provides an in depth analysis of states in India with respect to the National Family Health Survey-4 (NFHS-4 ...
Ankita Dey, Kunal K Majumdar, Arun Kumar Chakraborty, Asok Kumar Mandal   +3 more
doaj  

Landslide Emergency Response Preparedness in Mining Areas: Early Warning System Implementation

The Indonesian Journal of Occupational Safety and Health
Introduction: Coal mining operations present serious risks due to landslip risks, necessitating the use of efficient early warning systems and emergency preparation. This paper examines the use of an early warning system called LASER (Land Sliding Alert)
Ardhila Chadarisman, Tedi Cahya Nusantara Herdianto   +1 more
doaj   +1 more source

Hypoparathyroidism in a Case of Transfusion Dependent Thalassemia

Journal of the ASEAN Federation of Endocrine Societies, 2020
Repeated blood transfusions in transfusion dependent thalassemia (TDT) leads to iron overload-related endocrine complications. Hypoparathyroidism (HPT) with severe signs of hypocalcemia is a recognized complication among these patients. A 14-year-old
Anirban Majumder, Sagar Basu
doaj   +1 more source