Results 71 to 80 of about 57,276 (230)

Hypoparathyroidism in a Case of Transfusion Dependent Thalassemia

Journal of the ASEAN Federation of Endocrine Societies, 2020
Repeated blood transfusions in transfusion dependent thalassemia (TDT) leads to iron overload-related endocrine complications. Hypoparathyroidism (HPT) with severe signs of hypocalcemia is a recognized complication among these patients. A 14-year-old
Anirban Majumder, Sagar Basu
doaj   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Interplay between Klebsiella pneumoniae producing KPC-31 and KPC-3 under treatment with high dosage meropenem. A case report

, 2022
The objective was to study ceftazidime-avibactam resistant and susceptible Klebsiella pneumoniae isolated from a patient admitted to the Policlinico Umberto I of Rome for SARS-CoV2.
Oliva A., Raponi G., Carattoli A., Venditti M., Sacco F., Tomolillo D., Di Lella F. M., Curtolo A., Arcari G.   +8 more
core   +1 more source

In vitro activity of the  -lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases [PDF]

Journal of Antimicrobial Chemotherapy, 2009
NXL104 is a novel-structure beta-lactamase inhibitor with potent activity against both class A and class C enzymes. Among the class A carbapenemases, KPC-type enzymes are now spreading rapidly and KPC-related carbapenemase resistance is an emerging phenomenon of great clinical importance.
Stachyra, Thérèse, Levasseur, Premavathy, Péchereau, Marie-Claude, Girard, Anne-Marie, Claudon, Monique, Miossec, Christine, Black, Michael T.   +6 more
openaire   +2 more sources

Endocrine Therapy of Adult Gender-Incongruent Individuals Seeking Gender Reaffirmation

Indian Journal of Plastic Surgery, 2022
Gender-affirming hormone therapy (GAHT) is integral to the management of gender-incongruent (GI) individuals. GAHT greatly improves the quality of life for GI individuals.
Anirban Majumder
doaj   +1 more source

Towards Credible GHG Reporting: The Role of GHG Assurance and Assurance Providers in Firm Valuation

Abacus, EarlyView.
The demand for greenhouse gas (GHG) emissions disclosures is rising globally; yet, the credibility of such information remains uncertain when assurance is not mandated. Drawing on a sample of firms from 43 countries, this study examines the role of GHG assurance and the choice of assurance provider in the market value effects of GHG emissions.
Sudipta Bose, Maria Balatbat, Wendy Green   +2 more
wiley   +1 more source

KPC with ESBL: A multistarrer tragedy

Annals of Tropical Medicine and Public Health, 2016
Background: One of the most dangerous carbapenemase is Klebsiella pneumoniae Carbapenemase or KPC, possessing the ability to hydrolyze the Carbapenems, and other beta-lactams as well like Penecillins, Cephalosporins, and aztreonam. Many members of the family Enterobacteriaceae and few other non-fermenters contain the gene blaKPC, which codes for the
Dibyendu Banerjee, Baishali Chakraborty, Arpita Nandan, Banya Chakraborty   +3 more
openaire   +1 more source

Carbapenem resistance in gram-negative pathogens in an Iranian hospital: high prevalence of OXA-type carbapenemase genes [PDF]

Clinical and Experimental Pediatrics
Background The widespread dissemination of carbapenem-resistant gram-negative bacteria poses a significant threat to global public health. Purpose This study aimed to investigate the prevalence of carbapenem resistance in gram-negative bacteria isolated ...
Setareh Mamishi, Reihaneh Hosseinpour Sadeghi, Sadaf Sajedi Moghaddam, Babak Pourakbari, Shiva Poormohammadi, Maryam Sotoudeh Anvari, Shima Mahmoudi   +6 more
doaj   +1 more source

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

Emergence of KPC-2 and KPC-3 in Carbapenem-Resistant Klebsiella pneumoniae Strains in an Israeli Hospital [PDF]

Antimicrobial Agents and Chemotherapy, 2007
ABSTRACT Carbapenem resistance due to KPC has rarely been observed outside the United States. We noticed a sharp increase in carbapenem-resistant Klebsiella pneumoniae strains possessing KPC in Tel Aviv Medical Center from 2004 to 2006.
Azita, Leavitt, Shiri, Navon-Venezia, Inna, Chmelnitsky, Mitchell J, Schwaber, Yehuda, Carmeli   +4 more
openaire   +2 more sources