Results 21 to 30 of about 32,597 (198)

[Effects of Krüppel-like factor 4 on inflammatory response and organ injury in septic mice]. [PDF]

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi, 2022
Wang YW, Liu Y, Cao P, Zhang QY, Chen Y, Li SH, Guan H.   +6 more
europepmc   +3 more sources

Sentrin-specific protease 3 (SENP3)-mediated Krüppel-like factor 4 (KLF4) deSUMOylation regulates vascular smooth muscle cell phenotypic switching in atherosclerosis. [PDF]

Mol Biomed
Wang Z, Wang Y, Yuan R, Ji Q, Li Y, Huo H, Zhou G, Yan X, Shen L, Cai Z, He B.   +10 more
europepmc   +2 more sources

Author Correction: MircoRNA-145 promotes activation of hepatic stellate cells via targeting krüppel-like factor 4 [PDF]

Scientific Reports, 2023
Ruoting Men, Maoyao Wen, Mingyue Zhao, Xuelian Dan, Zongze Yang, Wenchao Wu, Maggie Haitian Wang, Xiaojing Liu, Li Yang   +8 more
doaj   +2 more sources

Intestinal epithelial Krüppel-like factor 4 alleviates endotoxemia and atherosclerosis through improving NF-κB/miR-34a-mediated intestinal permeability. [PDF]

Acta Pharmacol Sin
Nie HZ, Zhou YW, Yu XH, Yin CG, Li LF, Hao HQ, Yuan T, Pan Y.   +7 more
europepmc   +3 more sources

KLF4 suppresses the proliferation and metastasis of NSCLC cells via inhibition of MSI2 and regulation of the JAK/STAT3 signaling pathway

Translational Oncology, 2022
Background: Non-small cell lung cancer (NSCLC) remains an aggresive tumor with poor survival rates. Krüppel-like factor 4 (KLF4) is known to be involved in progression of NSCLC; however, the detailed mechanism by which KLF4 regulates the progression of ...
Di-Di Luo, Feng Zhao
doaj   +1 more source

Krüppel-like factor 4 modulates the miR-101/COL10A1 axis to inhibit renal fibrosis after AKI by regulating epithelial-mesenchymal transition. [PDF]

Ren Fail
Zhao J, Wang X, Wu Y, Zhao C.
europepmc   +3 more sources

Overexpression of Krüppel-Like Factor 4 Suppresses Migration and Invasion of Non-Small Cell Lung Cancer Through c-Jun-NH2-Terminal Kinase/Epithelial-Mesenchymal Transition Signaling Pathway

Frontiers in Pharmacology, 2020
Krüppel-like factor 4 (KLF4) is a transcription factor and plays a vital role in cancer initiation and development. However, the role of Krüppel-like factor 4 in the metastasis of non-small cell lung cancer (NSCLC) is not clear.
Yanping Wu, Lianjun Lin, Xiang Wang, Yong Li, Zhonghui Liu, Wei Ye, Weiming Huang, Gang Lin, Haibo Liu, Jixin Zhang, Ting Li, Beilei Zhao, Liping Lv, Jian Li, Nanping Wang, Xinmin Liu   +15 more
doaj   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Differentiated serum levels of Krüppel-like factors 2 and 4, sP-selectin, and sE-selectin in patients with gestational diabetes mellitus

Gynecological Endocrinology, 2022
Objectives This study aims to determine serum levels of human Krüppel-like factors (KLFs), sP-selectin and sE-selectin and establish correlations between them in patients with gestational diabetes mellitus (GDM).Methods Twenty-six GDM patients aged ...
Hongmei Zhang#, Zhigao Chen#, Xiaoling Wang   +2 more
doaj   +1 more source

Krüppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation.

PLoS ONE, 2014
The role of different lineage specific transcription factors in directing hematopoietic cell fate towards myeloid lineage is well established but the status of epigenetic modifications has not been defined during this important developmental process.
Manjula Karpurapu, Ravi Ranjan, Jing Deng, Sangwoon Chung, Yong Gyu Lee, Lei Xiao, Teja Srinivas Nirujogi, Jeffrey R Jacobson, Gye Young Park, John W Christman   +9 more
doaj   +1 more source