Results 1 to 10 of about 205,719 (255)
Ewolucja pozycji Narodowego Banku Polskiego w polityce makroostrożnościowej
Seminare, 2022 Artykuł poświęcony jest pozycji Narodowego Banku Polskiego w nadzorze makroostrożnościowym. Pierwotnie za nadzór makroostrożnościowy w Polsce miała odpowiadać Rada Ryzyka Systemowego, w której próbowano zagwarantować wiodącą rolę NBP z różnym nasileniem.
Ireneusz Kraś
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Evaluation of the Role of the KRAS Gene Polymorphism LCS6 (rs61764370) in Iraqi Women with Ovarian Cancer [PDF]
Archives of Razi Institute, 2022 In carcinogenesis, KRAS is an essential oncogene that plays a key function. The polymorphism of rs61764370 is a candidate for cancer susceptibility in KRAS3' untranslated region.
M Ghazi Jumaa
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Structure, 2017 Mutations in members of the RAS family of small GTPases have been associated with numerous human cancers. However, RAS family members are notoriously difficult to target. In this issue of Structure, Lu et al. (2017) examine the effects of two compounds with distinct chemical scaffolds on the structure and dynamics of an oncogenic KRAS mutant, thus ...
Daniel J, Deredge, Patrick L, Wintrode
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Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2022 Colorectal cancer is one of the most frequently diagnosed malignant tumors in men and women, which is a highly heterogeneous group of neoplasms consisting of subclasses with different molecular and clinical characteristics, and, as a consequence ...
A. N. Toropovskiy +5 more
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Escaping KRAS: Gaining Autonomy and Resistance to KRAS Inhibition in KRAS Mutant Cancers
Cancers, 2021 Activating mutations in KRAS are present in 25% of human cancers. When mutated, the KRAS protein becomes constitutively active, stimulating various effector pathways and leading to the deregulation of key cellular processes, including the suppression of apoptosis and enhancement of proliferation.
Yuta Adachi +3 more
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Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer. [PDF]
, 2012 Thus, we evaluated the immunofluorescence pattern of TRAIL-receptors and E-cadherin to assess the fraction of membrane-bound TRAIL-receptors in 231 selected patients with early-stage CRC undergoing surgical treatment only.
De Toni, Enrico N. +10 more
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The prevalence of KRAS and BRAF mutation in colorectal cancer patients in Bali
Indonesian Journal of Biotechnology, 2022 Mutations in the KRAS (Kirsten rat sarcoma viral oncogene homolog gene) and BRAF (v‐Raf murine sarcoma viral oncogene homolog B1) gene play a significant role in primary resistance to colorectal cancer therapy.
Ayu Dewi Ni Nyoman +4 more
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Cold Spring Harbor Perspectives in Medicine, 2018 Oncogenic Kras are genetic dependencies for the majority of pancreatic and colorectal adenocarcinomas; however, much remains to be understood regarding its tropism to these carcinomas. Recently developed organoid technology presents a more representative model culture system for pancreatic and colon epithelial tissues as well as better fostering the ...
Derek, Cheng, David, Tuveson
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Gradišča Komenskega Krasa v starejši železni dobi
Arheološki Vestnik, 2021 Prispevek prinaša nova spoznanja o poselitvi Komenskega Krasa v starejši železni dobi. Podrobneje so obravnavana tri v arheološki literaturi že znana najdišča, to so Tomaj, Štanjel in Zagrajec, kjer so bile v zadnjih desetletjih izvedene arheološke ...
Patricija BRATINA
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Notranjska v pozni bronasti in starejši železni dobi
Arheološki Vestnik, 2021 Prispevek v uvodnem delu prinaša pregled zgodovine raziskav prazgodovinskih najdišč na Notranjskem. V nadaljevanju so predstavljene tri arheološke lokacije, ki dobro zaobjamejo pozno bronasto in starejšo železno dobo notranjske halštatske skupnosti ...
Alma BAVDEK
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