Results 21 to 30 of about 151,900 (300)

Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer. [PDF]

, 2012
Thus, we evaluated the immunofluorescence pattern of TRAIL-receptors and E-cadherin to assess the fraction of membrane-bound TRAIL-receptors in 231 selected patients with early-stage CRC undergoing surgical treatment only.
Göke, Burkhard, Thomas Kirchner (109827), Rene Jackstadt, Gallmeier, Eike, Thomas Kirchner, Gerbes, Alexander L., Kriegl, Lydia, Eike Gallmeier, Jackstadt, Rene, Alexander L Gerbes, Burkhard Göke (109829), De Toni, Enrico N., Eike Gallmeier (109823), Enrico N De Toni, Burkhard Göke, Horst, David, Andreas Jung, Rene Jackstadt (109815), David Horst, Jung, Andreas, Antonia Rizzani (109811), Heiko Hermeking (109819), Alexander L. Gerbes (109825), Kirchner, Thomas, Andreas Jung (109804), David Horst (109808), Enrico N. De Toni (109830), Lydia Kriegl, Rizzani, Antonia, Hermeking, Heiko, Heiko Hermeking, Lydia Kriegl (109801), Antonia Rizzani   +32 more
core   +2 more sources

Malignant Melanoma within a Cellular Blue Nevi Presenting as a Vascular Malformation and the Connection to Sporadic KRAS Mutations

Case Reports in Dermatology, 2021
We present a case of malignant melanoma (MM) developing within a vascular malformation showing features of cellular blue nevi. A 47-year-old male presented with acute symptoms of a temporal and zygomatic mass, which were both previously asymptomatic upon
Felicia Tai, Vitor M. Pereira, Sam Babak, Ivan Radovanovic, Shachar Sade, Tara Lynn Teshima   +5 more
doaj   +1 more source

Detection of activating mutations in RAS/RAF/MEK/ERK and JAK/STAT signaling pathways [PDF]

Терапевтический архив, 2020
Issue.The study of activating mutations (NRAS,KRAS,FLT3,JAK2,CRLF2genes) of RAS/RAF/MEK/ERK and JAK/STAT signaling pathways in B-cell acute lymphoblastic leukemia (B-ALL) in adult patients which are included in Russian multicenter clinical trials ...
K. I. Zarubina, E. N. Parovichnikova, V. L. Surin, O. S. Pshenichnikova, O. A. Gavrilina, G. A. Isinova, V. V. Troitskaia, A. N. Sokolov, I. V. Gal’tseva, N. M. Kapranov, Iu. O. Davydova, T. N. Obukhova, A. B. Sudarikov, V. G. Savchenko   +13 more
doaj   +1 more source

Cancer-associated mutations in endometriosis reframe a benign disease through molecular oncology. [PDF]

Mol Oncol
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Mujacic C, Vitale MC, Siino R, Di Giovanni E, Ferrante Bannera C, Di Marco E, Gottardo A, Russo TDB, Barraco N, Perez A, Gristina V, Galvano A, Badalamenti G, Russo A, Bazan V, Incorvaia L.   +15 more
europepmc   +2 more sources

Bp Józef Sebastian Pelczar. Wybór pism

Nasza Przeszłość, 1968
Tom 29 "Naszej Przeszłości" zawiera wybór pism bpa Józefa Sebastiana Pelczara. Był on człowiekiem o wielkim bogactwie intelektualnym i duchowym, o wszechstronnych zainteresowaniach. Zasłynął  już współcześnie jako jeden z najbardziej popularnych pisarzy
Modesta Kras
doaj   +1 more source

Nesting of Eurasian Crag Martin (Ptyonoprogne rupestris) in the Malá Fatra Mts. in Slovakia

Tichodroma, 2022
We detected occurrence and nesting of Eurasian Craig Martin (Ptyonoprogne rupestris) for the first time in Slovakia. One nesting pair with four juveniles was detected during the 2022 nesting season in the Malá Fatra mountains.
Štefan Matis, Miroslav Fulín, Tomáš Flajs   +2 more
doaj   +1 more source

Molecular genetic testing in colon cancer: clinical aspects

Alʹmanah Kliničeskoj Mediciny, 2022
Molecular genetic diagnostics is an essential element to plan for management of colorectal cancer (CRC) patients. The choice of systemic treatment for CRC is impossible without molecular testing of the tumor.
Aleksandr S. Martianov, Ekaterina Sh. Kuligina, Alexandr A. Romanko, Evgeny N. Imyanitov   +3 more
doaj   +1 more source

„Jak chwytać lisy w Pańskiej winnicy”? Treści antyheretyckie w kazaniach św. Bernarda z Clairvaux i Hélinanda z Froidmont

Roczniki Historyczne, 2014
„Wie sollen die Füchse im Weinberg des Herrn gefangen werden?” Antihäretische Inhalte in den Predigten Bernhards von Clairvaux und Helinands von Froidmont Zusammenfassung Seit der Mitte des 12.
Paweł Kras
doaj   +1 more source

Targeting KRAS mutations with HLA class II-restricted TCRs for the treatment of solid tumors

OncoImmunology, 2021
T-cell receptor (TCR) redirected T cells are considered as the next generation of care for the treatment of numerous solid tumors. KRAS mutations are driver neoantigens that are expressed in over 25% of all cancers and are thus regarded as ideal targets ...
Pierre Dillard, Nicholas Casey, Sylvie Pollmann, Patrik Vernhoff, Gustav Gaudernack, Gunnar Kvalheim, Sébastien Wälchli, Else Marit Inderberg   +7 more
doaj   +1 more source

Biomarker series: KRAS- A narrative review

Cancer Research, Statistics, and Treatment, 2021
Non-small cell lung cancer (NSCLC) has emerged as the poster child of molecular medicine. Kirsten rat sarcoma (KRAS)-mutated NSCLC is a common yet heterogeneous entity with distinct clinical and prognostic characteristics.
Ullas Batra, Shrinidhi Nathany
doaj   +1 more source