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Menulis Teks Eksplanasi Ilmiah Dengan Menggunakan Media Media Flash Card

open access: yesIbriez: Jurnal Kependidikan Dasar Islam Berbasis Sains, 2019
Kemampuan menulis kelas VI sekolah dasar adalah kemampuan menulis teks penjelasan (eksplanasi) dengan menggunakan kosa kata baku dan kalimat efektif. Namun pada kenyataannya, siswa kelas VI SDN Rejomulyo 1 Kras Kediri masih kesulitan menulis karangan ...
Bambang Setyawan
doaj   +1 more source

Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis. [PDF]

open access: yes, 2015
BackgroundKey effector(s) of mutated KRAS in lung cancer progression and metastasis are unknown. Here we investigated the role of PAK1/Crk axis in transduction of the oncogenic KRAS signal in non-small cell lung cancer (NSCLC).MethodsWe used NSCLC ...
Aljilani, Amir   +7 more
core   +2 more sources

An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer [PDF]

open access: yes, 2017
KRAS mutated tumours represent a large fraction of human cancers, but the vast majority remains refractory to current clinical therapies. Thus, a deeper understanding of the molecular mechanisms triggered by KRAS oncogene may yield alternative ...
Andersen, Jesper B.   +22 more
core   +3 more sources

KRAS Mouse Models: Modeling Cancer Harboring KRAS Mutations [PDF]

open access: yesGenes & Cancer, 2011
KRAS is a potent oncogene and is mutated in about 30% of all human cancers. However, the biological context of KRAS-dependent oncogenesis is poorly understood. Genetically engineered mouse models of cancer provide invaluable tools to study the oncogenic process, and insights from KRAS-driven models have significantly increased our understanding of the ...
Rónán C, O'Hagan, Joerg, Heyer
openaire   +2 more sources

INFLUENCE OF SOMATIC MUTATIONS OF KRAS, NRAS, BRAF AND MICROSATELLITE INSTABILITY STATUS ON SURVIVAL OF COLORECTAL CANCER PATIENTS WITH PERITONAL CARCINO

open access: yesСибирский онкологический журнал, 2020
Purpose: to evaluate the effect of somatic mutations of the KRAS, NRAS, BRAF genes and the status of microsatellite instability on the overall and disease-free survival of patients undergoing cytoreductive surgery with hyperthermic intraperitoneal ...
V. P. Shubin   +6 more
doaj   +1 more source

Impact of the Specific Mutation in KRAS Codon 12 Mutated Tumors on Treatment Efficacy in Patients with Metastatic Colorectal Cancer Receiving Cetuximab-Based First-Line Therapy: A Pooled Analysis of Three Trials [PDF]

open access: yes, 2012
Purpose: This study investigated the impact of specific mutations in codon 12 of the Kirsten-ras (KRAS) gene on treatment efficacy in patients with metastatic colorectal cancer (mCRC).
Allegra CJ   +41 more
core   +1 more source

„Jak chwytać lisy w Pańskiej winnicy”? Treści antyheretyckie w kazaniach św. Bernarda z Clairvaux i Hélinanda z Froidmont

open access: yesRoczniki Historyczne, 2014
„Wie sollen die Füchse im Weinberg des Herrn gefangen werden?” Antihäretische Inhalte in den Predigten Bernhards von Clairvaux und Helinands von Froidmont Zusammenfassung Seit der Mitte des 12.
Paweł Kras
doaj   +1 more source

Malignant Melanoma within a Cellular Blue Nevi Presenting as a Vascular Malformation and the Connection to Sporadic KRAS Mutations

open access: yesCase Reports in Dermatology, 2021
We present a case of malignant melanoma (MM) developing within a vascular malformation showing features of cellular blue nevi. A 47-year-old male presented with acute symptoms of a temporal and zygomatic mass, which were both previously asymptomatic upon
Felicia Tai   +5 more
doaj   +1 more source

Detection of activating mutations in RAS/RAF/MEK/ERK and JAK/STAT signaling pathways [PDF]

open access: yesТерапевтический архив, 2020
Issue.The study of activating mutations (NRAS,KRAS,FLT3,JAK2,CRLF2genes) of RAS/RAF/MEK/ERK and JAK/STAT signaling pathways in B-cell acute lymphoblastic leukemia (B-ALL) in adult patients which are included in Russian multicenter clinical trials ...
K. I. Zarubina   +13 more
doaj   +1 more source

High-Resolution Three-Dimensional NMR Structure Of The KRAS Proto-Oncogene Promoter Reveals Key Features Of A G-Quadruplex Involved In Transcriptional Regulation [PDF]

open access: yes, 2017
Non-canonical base pairing within guanine-rich DNA and RNA sequences can produce G-quartets, whose stacking leads to the formation of a G-quadruplex (G4).
Ivashchenko, S.   +5 more
core   +2 more sources

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