Results 211 to 220 of about 130,425 (315)

Activating KRAS Mutations Expressed in 3D Endothelial Spheroids Induce Blebbing Morphologies Associated with Amoeboid-like Migration. [PDF]

Cells
McRobb LS, Lee VS, Stoodley MA.
europepmc   +1 more source

Combination of transvaginal ultrasound with cervical cancer screening contributes to early detection of ovarian cancer: Clinical trial

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Early detection of ovarian cancer at stage I is important to improve patients‘ prognosis. The goal of this study was to examine if transvaginal ultrasound (TVU) performed at the same time as cervical cancer screening can facilitate early detection of ovarian cancer.
Hiromasa Fujita, Kazuhira Okamoto, Hidenori Kato, Hidemichi Watari, Nobuyoshi Ozawa, Mitsuaki Suzuki   +5 more
wiley   +1 more source

KRAS^G12D mutation promotes pancreatic tumorigenesis by suppressing sirtuin three via the guanine nucleotide exchange factor RCC1. [PDF]

J Biol Chem
Mai T, Wang M, Qiu Y, Lu W, Wu H, Chen S, Chiao PJ, Huang P.   +7 more
europepmc   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

Interdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li, Shun Wang, Guowei Zhao, Jiangtao Li, Xin Li, Bingning Wang, Yi Zhang, Mengfei Yao, Lei Guo, Jianming Ying, Wenbin Li   +10 more
wiley   +1 more source

Tumor suppressor genes and KRAS G12C inhibitor resistance in non-small cell lung cancer. [PDF]

iScience
Zhu L, Jia X, Xu L, Chen L, Fu X, Yan H, Ai B, Peng S.   +7 more
europepmc   +1 more source

Small Nucleotide Variant Analysis Using RNA Fusion Panel (SMURF): Making the Most of RNAseq Data in Solid Tumours

Journal of Clinical Laboratory Analysis, EarlyView.
RNA‐based fusion panels using targeted next‐generation sequencing of formalin‐fixed paraffin‐embedded (FFPE) tumour tissue specimens have been used for a few years from patients with various tumour types to detect rearrangements/fusions. Using the bioinformatic approaches the data obtained from RNA sequencing (RNAseq) can also be used for small ...
Pranav Dorwal, Julie Robin, Broden Krause, Patricia Pyrchla, Bin Yuan, Robert Quach, Anna Fong Na Goh, Pamela Htain, Noel Djitro, Amit Kumar, Liyan Song, Priscillia Siswara, Suzanne Svobodova, Peter Kaub, Beena Kumar   +14 more
wiley   +1 more source

Targeting KRAS mutations: orchestrating cancer evolution and therapeutic challenges. [PDF]

Signal Transduct Target Ther
Choucair K, Imtiaz H, Uddin MH, Nagasaka M, Al-Hallak MN, Philip PA, El-Rayes B, Pasche BC, Azmi AS.   +8 more
europepmc   +1 more source

The current understanding of KRAS oligomerization on membranes

Nastazia Lesgidou, Michail Papadourakis, Nishita Mandal, Sepehr Dehghani‐Ghahnaviyeh, Camilo Velez‐Vega, José S. Duca, Zoe Cournia   +6 more
openalex   +1 more source

Reptiles of Phetchaburi Province, Western Thailand: a list of species, with natural history notes, and a discussion on the biogeography at the Isthmus of Kra

, 2003
Olivier S. G. Pauwels, Patrick David, CHUCHEEP CHIMSUNCHART, Anchalee Aowphol   +3 more
openalex   +1 more source

Impact of Baseline Nutritional Status, Psychological Health, Fatigue, and Insomnia on Outcomes of Immune Checkpoint Inhibitors in Advanced Non‐Small Cell Lung Cancer: A Retrospective Cohort Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the impact of pretreatment nutritional status, psychological health, fatigue, and insomnia on outcomes of immune checkpoint inhibitors (ICIs) monotherapy in patients with advanced non‐small cell lung cancer (NSCLC). A total of 80 patients with stage IV NSCLC were enrolled.
Yu‐Xuan Zhu, Yuan‐Yuan Zhang, Xiu‐Juan Jiang   +2 more
wiley   +1 more source