Results 161 to 170 of about 3,153,249 (347)

Trematode infection buffers heat stress in blue mussels Mytilus edulis: The role of heat shock proteins

Journal of Animal Ecology, EarlyView.
The study shows that parasite infection changes heat shock protein expression and can increase heat tolerance in blue mussels. By separating parasite and temperature effects, the results suggest that infection may improve survival during heat stress, highlighting important parasite–host interactions for climate change resilience. Abstract The influence
Annika Greve, Jesper G. Sørensen, Mikael K. Sejr, Jakob Thyrring   +3 more
wiley   +1 more source

Determining the Survival Impact and Cost‐Effectiveness of Multi‐Gene Panel Sequencing in Metastatic Colorectal Cancer With Super Learning Approaches

Health Services Research, EarlyView.
ABSTRACT Objective To determine the effectiveness and cost‐effectiveness of multi‐gene panel sequencing compared to single‐gene KRAS testing for metastatic colorectal cancer (mCRC). Study Setting and Design British Columbia, Canada (BC) is a provincial single‐payer public healthcare system, and it was the first province to publicly reimburse multi‐gene
Emanuel Krebs, Deirdre Weymann, Howard J. Lim, Stephen Yip, Dean A. Regier   +4 more
wiley   +1 more source

The predatory behavior of ants: an impressive panoply of morphological adaptations

Insect Science, EarlyView.
This review focuses on predation in ants, showing the wide diversity of cases from solitary foraging to group hunting tactics, as well as the evolution of mandible shape frequently adapted to capture specific prey. Although most ants are generalist feeders, finding their sugary substances directly on plants or indirectly via sap‐sucking insects, some ...
Alain Dejean, Xim Cerdá, Jérôme Orivel, Frédéric Azémar, Alexander L. Wild, Bruno Corbara, Axel Touchard   +6 more
wiley   +1 more source

Metabolomic profiling of pheochromocytomas in dogs: Catecholamine phenotype and tricarboxylic acid cycle metabolites

Journal of Veterinary Internal Medicine
Background In humans with pheochromocytomas (PCCs), targeted metabolomics is used to determine the catecholamine phenotype or to uncover underlying pathogenic variants in tricarboxylic acid (TCA) cycle genes such as succinate dehydrogenase subunits (SDHx)
Marit F. van denBerg, Nicole Bechmann, Hans S. Kooistra, Monique E. vanWolferen, Elpetra P. M. Timmermans‐Sprang, Mirko Peitzsch, Sara Galac   +6 more
doaj   +1 more source

Host Exploitation by Cuckoos in China: A Review and Real‐Time Tracking Program for Parasitism Records

Integrative Zoology, EarlyView.
China is a global hotspot for cuckoo‐host diversity, with 17 cuckoo species, exploiting 142 host species. We reveal adaptive matching in body size and egg traits, along with niche partitioning among cuckoos, while identifying eight new host species.
Tao Liu, Canchao Yang
wiley   +1 more source

Glutamate-Induced Deregulation of Krebs Cycle in Mitochondrial Encephalopathy Lactic Acidosis Syndrome Stroke-Like Episodes (MELAS) Syndrome Is Alleviated by Ketone Body Exposure. [PDF]

Biomedicines, 2022
Belal S, Goudenège D, Bocca C, Dumont F, Chao De La Barca JM, Desquiret-Dumas V, Gueguen N, Geffroy G, Benyahia R, Kane S, Khiati S, Bris C, Aranyi T, Stockholm D, Inisan A, Renaud A, Barth M, Simard G, Reynier P, Letournel F, Lenaers G, Bonneau D, Chevrollier A, Procaccio V.   +23 more
europepmc   +1 more source

Measuring Propidium Iodide Brightness as a Function of Viability: A High‐Throughput Quantitative Assessment of Hepatic Spheroids

Artificial Organs, EarlyView.
The graphical abstract illustrates our rapid PI‐based spheroid viability assay: hepatocyte spheroids are formed and stained with AO/PI, imaged after a 15‐min incubation, and analyzed for PI brightness normalized to area. This metric correlates strongly with functional urea/DNA output, validating PI intensity as a fast, reliable indicator of spheroid ...
Michael G. Megaly, Diane Tobolt, Bat‐Erdene Namsrai, Benjamin Fisher, Anthony An‐Fa Dahm Chen, Joseph Sushil Rao, Srivasupradha Ramesh, Anudari Chimedtseren, Mark Clemens, Charles Y. Lee, John C. Bischof, Erik B. Finger   +11 more
wiley   +1 more source

Mitochondrial respiratory chain and Krebs cycle enzyme function in human donor livers subjected to end-ischaemic hypothermic machine perfusion. [PDF]

PLoS One, 2021
Abudhaise H, Taanman JW, DeMuylder P, Fuller B, Davidson BR.   +4 more
europepmc   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Mitochondrial Dysfunction and Reduced TCA Cycle Metabolite Levels in Inflammatory Bowel Disease Patients

Journal of Inflammation Research
Ewa Dudzińska,1 Agnieszka Madro,2 Ann Katrin Sauer,3,4 Andreas M Grabrucker,3– 5 Aneta Strachecka6 1Department of Dietetics and Nutrition Education, Medical University of Lublin, Lublin, Poland; 2Department of Gastroenterology with Endoscopic Unit,
Dudzińska E, Madro A, Sauer AK, Grabrucker AM, Strachecka A   +4 more
doaj