Results 161 to 170 of about 51,377 (282)

The Efficiency of the Krebs Cycle and the Respiratory Chain in Physiologically and Prematurely Aging Bees (<i>Apis mellifera</i>). [PDF]

Int J Mol Sci
Kunat-Budzyńska M, Staniszewska P, Olszewski K, Cytryńska M, Strachecka A.   +4 more
europepmc   +1 more source

Long‐term adverse cardiovascular changes induced by cocoa shell extract administration through lactation in fetal undernourished and control rats

Experimental Physiology, EarlyView.
Abstract Cocoa shell extract (CSE; rich in antioxidant compounds) administered to adult hypertensive rats exposed to fetal undernutrition (MUN) reduces blood pressure, improving cardiovascular alterations. We aimed to explore lactation as a reprogramming window, evaluating the long‐term effects of CSE supplementation during this period. MUN and control
Santiago Ruvira, Pilar Rodríguez‐Rodríguez, Metee Iampanichakul, Begoña Quintana‐Villamandos, Dolores Morales, David Ramiro‐Cortijo, Silvia M. Arribas   +6 more
wiley   +1 more source

Timing‐dependent protective and therapeutic effects of ethyl pyruvate in trinitrobenzene sulfonic acid‐induced experimental colitis

Experimental Physiology, EarlyView.
Abstract Ulcerative colitis (UC) involves excessive inflammation, extracellular matrix remodelling and oxidative stress. Ethyl pyruvate (EP) exhibits anti‐inflammatory effects, but the comparative efficacy of prophylactic versus therapeutic administration and timing‐dependent molecular responses remains unclear.
Hatice Yorulmaz, Elif Yorulmaz, Elif Özkök, Suat Hayri Küçük, Erdem Sünger, Ayyub Ebrahimi, Beyza Yılmaz, Serdar Altınay   +7 more
wiley   +1 more source

Author Correction: Air pollution-derived particulate matter dysregulates hepatic Krebs cycle, glucose and lipid metabolism in mice. [PDF]

Sci Rep, 2020
Reyes-Caballero H, Rao X, Sun Q, Warmoes MO, Lin P, Sussan TE, Park B, Fan TW, Maiseyeu A, Rajagopalan S, Girnun GD, Biswal S.   +11 more
europepmc   +1 more source

Modeling Krebs cycle from liver, heart and hepatoma mitochondria, supported Complex I as target for specific inhibition of cancer cell proliferation. [PDF]

Front Oncol
Hernández-Esquivel L, Del Mazo-Monsalvo I, Pacheco-Velázquez SC, Feregrino-Mondragón RD, Robledo-Cadena DX, Sánchez-Thomas R, Jasso-Chávez R, Saavedra E, Marín-Hernández Á.   +8 more
europepmc   +1 more source

Impairments in mitochondrial dynamics and morphology in skeletal muscle of breast cancer patients after a single paclitaxel administration

Experimental Physiology, EarlyView.
Abstract Standard chemotherapy regimens for patients with breast cancer are based on epirubicin–cyclophosphamide (EC) and paclitaxel (TAX) administrations. While it has been shown that first EC administration impairs mitochondrial homeostasis, the isolated effects of TAX have not been studied without previous chemotherapy exposure.
Joris Mallard, Elyse Hucteau, Laura Somme, Hervé Bischoff, Valérie Demais, Pauline Silvestrin, Anne‐Laure Charles, Roland Schott, Xavier Pivot, Thomas J. Hureau, Allan F. Pagano   +10 more
wiley   +1 more source

Substrate‐specific mitochondrial dysfunction and metabolomic profiles in type 2 diabetic rat hearts

Experimental Physiology, EarlyView.
Abstract Type 2 diabetes (T2D) greatly alters cardiac fuel handling, yet how mitochondrial function adapts to the diabetic substrate environment remains unclear. This study investigated substrate‐specific cardiac mitochondrial bioenergetics from a T2D rat model induced by a high‐fat diet and low‐dose streptozotocin.
Toan Pham
wiley   +1 more source

A prebiotic Krebs cycle analog generates amino acids with H₂ and NH₃ over nickel. [PDF]

Chem
Kaur H, Rauscher SA, Werner E, Song Y, Yi J, Kazöne W, Martin WF, Tüysüz H, Moran J.   +8 more
europepmc   +1 more source

Metabolic phenotype of tumors related to Krebs cycle dysfunction

, 2015
Le cycle de Krebs occupe une place centrale dans le métabolisme cellulaire et est le point de jonction de nombreuses voies essentielles. Depuis le début des années 2000, un lien a été démontré entre l’apparition de certains cancers et des mutations ...
Janin, Maxime
core  

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source