Results 71 to 80 of about 193,609 (276)
BACKGROUND: The genetic condition β-thalassemia causes a deficit in the β-globin chain. Goblins are produced under the supervision of at least nine different genes.
Mayssam Makki Salih+2 more
doaj +1 more source
Interaction of PRP4 with Krüppel-Like Factor 13 Regulates CCL5 Transcription [PDF]
Abstract Activation of resting T lymphocytes initiates differentiation into mature effector cells over 3–7 days. The chemokine CCL5 (RANTES) and its major transcriptional regulator, Krüppel-like factor 13 (KLF13), are expressed late (3–5 days) after activation in T lymphocytes.
Lisa A. McPherson+4 more
openaire +3 more sources
Transcriptional silencing of HIV in CD4 T cells generates a reservoir of latently infected cells that can reseed infection after interruption of therapy.
Stuart R Jefferys+10 more
doaj +1 more source
Functional Characteristics of Gene Expression Motifs with Single and Dual Strategies of Regulation [PDF]
Transcriptional regulation by transcription factors and post-transcriptional regulation by microRNAs constitute two major modes of regulation of gene expression. While gene expression motifs incorporating solely transcriptional regulation are well investigated, the dynamics of motifs with dual strategies of regulation, i.e., both transcriptional and ...
arxiv +1 more source
The process of mitochondrial fission-fusion has been implicated in diverse neuronal roles including neuronal survival, axon degeneration, and axon regeneration.
Alexander Kreymerman+13 more
doaj +1 more source
The transcription factor “Kruppel-like factor 4” (KLF4) is a central player in the field of pluripotent stem cell biology. In particular, it was put under the spotlight as one of the four factors of the cocktail originally described for reprogramming ...
Nicolas O. Fortunel, Michèle T. Martin
doaj +1 more source
Androgen-induced rhox homeobox genes modulate the expression of AR-regulated genes [PDF]
Rhox5, the founding member of the reproductive homeobox on the X chromosome (Rhox) gene cluster, encodes a homeodomain-containing transcription factor that is selectively expressed in Sertoli cells, where it promotes the survival of male germ cells ...
Dandekar, D.+5 more
core +2 more sources
BackgroundEndometriosis is recognized as an estrogen-dependent inflammation disorder, estimated to affect 8%-15% of women of childbearing age. Currently, the etiology and pathogenesis of endometriosis are not completely clear.
Rong Geng+13 more
doaj +1 more source
Loss of Schlafen3 influences the expression levels of Schlafen family members in ileum, thymus, and spleen tissue [PDF]
Background The Schlafen (Slfn) family proteins are important for regulation of cell growth, cell differentiation and cell cycle progression. We sought to distinguish Slfn family expression in Slfn3 knockout (KO) mice after RNA sequencing analysis of ...
Emilie E. Vomhof-DeKrey+2 more
doaj +2 more sources
Background: Dysfunction of liver sinusoidal endothelial cells (LSECs) is permissive for the progression of liver fibrosis and cirrhosis and responsible for its clinical complications.
Tingting Su+7 more
doaj