Results 71 to 80 of about 193,609 (276)

The effect of ferritin level and gene expression of β-globin promoter with β-thalassemia patients in al-qadisiyah governorate, Iraq

open access: yesJournal of Applied Hematology, 2023
BACKGROUND: The genetic condition β-thalassemia causes a deficit in the β-globin chain. Goblins are produced under the supervision of at least nine different genes.
Mayssam Makki Salih   +2 more
doaj   +1 more source

Interaction of PRP4 with Krüppel-Like Factor 13 Regulates CCL5 Transcription [PDF]

open access: yesThe Journal of Immunology, 2007
Abstract Activation of resting T lymphocytes initiates differentiation into mature effector cells over 3–7 days. The chemokine CCL5 (RANTES) and its major transcriptional regulator, Krüppel-like factor 13 (KLF13), are expressed late (3–5 days) after activation in T lymphocytes.
Lisa A. McPherson   +4 more
openaire   +3 more sources

Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors.

open access: yesPLoS Pathogens, 2021
Transcriptional silencing of HIV in CD4 T cells generates a reservoir of latently infected cells that can reseed infection after interruption of therapy.
Stuart R Jefferys   +10 more
doaj   +1 more source

Functional Characteristics of Gene Expression Motifs with Single and Dual Strategies of Regulation [PDF]

open access: yesBiomed. Phys. Eng. Express, 2 , 025009(2016), 2016
Transcriptional regulation by transcription factors and post-transcriptional regulation by microRNAs constitute two major modes of regulation of gene expression. While gene expression motifs incorporating solely transcriptional regulation are well investigated, the dynamics of motifs with dual strategies of regulation, i.e., both transcriptional and ...
arxiv   +1 more source

MTP18 is a Novel Regulator of Mitochondrial Fission in CNS Neuron Development, Axonal Growth, and Injury Responses

open access: yesScientific Reports, 2019
The process of mitochondrial fission-fusion has been implicated in diverse neuronal roles including neuronal survival, axon degeneration, and axon regeneration.
Alexander Kreymerman   +13 more
doaj   +1 more source

When the Search for Stemness Genes Meets the Skin Substitute Bioengineering Field: KLF4 Transcription Factor under the Light

open access: yesCells, 2020
The transcription factor “Kruppel-like factor 4” (KLF4) is a central player in the field of pluripotent stem cell biology. In particular, it was put under the spotlight as one of the four factors of the cocktail originally described for reprogramming ...
Nicolas O. Fortunel, Michèle T. Martin
doaj   +1 more source

Androgen-induced rhox homeobox genes modulate the expression of AR-regulated genes [PDF]

open access: yes, 2010
Rhox5, the founding member of the reproductive homeobox on the X chromosome (Rhox) gene cluster, encodes a homeodomain-containing transcription factor that is selectively expressed in Sertoli cells, where it promotes the survival of male germ cells ...
Dandekar, D.   +5 more
core   +2 more sources

Gene expression analysis in endometriosis: Immunopathology insights, transcription factors and therapeutic targets

open access: yesFrontiers in Immunology, 2022
BackgroundEndometriosis is recognized as an estrogen-dependent inflammation disorder, estimated to affect 8%-15% of women of childbearing age. Currently, the etiology and pathogenesis of endometriosis are not completely clear.
Rong Geng   +13 more
doaj   +1 more source

Loss of Schlafen3 influences the expression levels of Schlafen family members in ileum, thymus, and spleen tissue [PDF]

open access: yesPeerJ, 2020
Background The Schlafen (Slfn) family proteins are important for regulation of cell growth, cell differentiation and cell cycle progression. We sought to distinguish Slfn family expression in Slfn3 knockout (KO) mice after RNA sequencing analysis of ...
Emilie E. Vomhof-DeKrey   +2 more
doaj   +2 more sources

Single-Cell Transcriptomics Reveals Zone-Specific Alterations of Liver Sinusoidal Endothelial Cells in CirrhosisSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2021
Background: Dysfunction of liver sinusoidal endothelial cells (LSECs) is permissive for the progression of liver fibrosis and cirrhosis and responsible for its clinical complications.
Tingting Su   +7 more
doaj  

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