HMGB1, a potential regulator of tumor microenvironment in KSHV-infected endothelial cells [PDF]
Myung-Ju Lee +8 more
openalex +1 more source
Cancer Biology of GSPT1: Mechanisms and Targeted Therapy Opportunities of Molecular Glue Degraders
This review systemically summarizes the structure, expression, regulatory networks, and isoform‐specific signaling of GSPT1 in cancers. According to the integration of GSPT1 targeted therapies, current challenges of GSPT1 targeted therapies are further analyzed, and provide therapeutic opportunities for the application of GSPT1 degraders in precision ...
Qiqi Lin +8 more
wiley +1 more source
Kaposi's Sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma, which is the most common cancer in acquired immune deficiency syndrome patients. KSHV contains a variety of immunoregulatory proteins. There have been many studies
Hyungtaek Jeon +6 more
doaj +1 more source
Supplementary Figure 2 from Targeting Sphingosine Kinase Induces Apoptosis and Tumor Regression for KSHV-Associated Primary Effusion Lymphoma [PDF]
Zhiqiang Qin +13 more
openalex +1 more source
Rare Presentation of Kaposi Sarcoma Mimicking Madura Foot: A Case Report
ABSTRACT Kaposi sarcoma (KS) is a low‐grade angioproliferative tumor primarily associated with HIV but also seen in immunocompetent individuals. Its presentation can mimic infectious diseases such as Madura foot (mycetoma), a chronic granulomatous infection endemic to tropical regions.
Jeminah Nyeenya Nakatudde +2 more
wiley +1 more source
An Interaction between KSHV ORF57 and UIF Provides mRNA-Adaptor Redundancy in Herpesvirus Intronless mRNA Export [PDF]
The hTREX complex mediates cellular bulk mRNA nuclear export by recruiting the nuclear export factor, TAP, via a direct interaction with the export adaptor, Aly.
Blackbourn, D.J. +9 more
core +4 more sources
Supplementary Figure 1 from A Purine Scaffold HSP90 Inhibitor BIIB021 Has Selective Activity against KSHV-Associated Primary Effusion Lymphoma and Blocks vFLIP K13-Induced NF-κB [PDF]
Gopalakrishnan Ramakrishnan +2 more
openalex +1 more source
ABSTRACT Background Castleman disease (CD) encompasses a range of heterogeneous non‐clonal lymphoproliferative disorders, including unicentric (UCD), and multicentric (MCD) forms. The latter is subdivided into HHV‐8+ MCD, POEMS‐MCD, and idiopathic‐MCD, not otherwise specified (iMCD‐NOS).
Caterina Cristinelli +14 more
wiley +1 more source
. Kaposi sarcoma-associated herpesvirus (KSHV) triggers the development of Kaposi sarcoma, a skin malignancy that is one of the most widespread defining symptoms in acquired immunodeficiency syndrome patients.
Yirui Xie +5 more
doaj +1 more source
Functional dissection of latency-associated nuclear antigen 1 of Kaposi's sarcoma-associated herpesvirus involved in latent DNA replication and transcription of terminal repeats of the viral genome [PDF]
Latency-associated nuclear antigen 1 (LANA1) of Kaposi's sarcoma-associated herpesvirus (KSHV) is implicated in the maintenance of the viral genome during latent infection.
Choe, Joonho +4 more
core +1 more source

