Results 11 to 20 of about 46,673 (194)
Cross-activating invariant NKT cells and kupffer cells suppress cholestatic liver injury in a mouse model of biliary obstruction. [PDF]
Both Kupffer cells and invariant natural killer T (iNKT) cells suppress neutrophil-dependent liver injury in a mouse model of biliary obstruction. We hypothesize that these roles are interdependent and require iNKT cell-Kupffer cell cross-activation ...
Caroline C Duwaerts +4 more
doaj +3 more sources
Correlation between Kupffer Cell Infiltration and Liver Parenchymal Cell Damages in Immunosuppressed Drugs-Induced Rats [PDF]
The liver is the largest organ in the body, composed of both parenchymal and non-parenchymal cells. Chemical substances and various drugs can induce liver injury and involve Kupffer cells which are non-parenchymal cells that release biologically active ...
Agni Febrina Pargaputri +2 more
doaj +3 more sources
Effects of zinc oxide nanoparticles on Kupffer cell phagosomal motility, bacterial clearance, and liver function [PDF]
Christa Y Watson, Ramon M Molina, Andressa Louzada, Kimberly M Murdaugh, Thomas C Donaghey, Joseph D BrainCenter for Nanotechnology and Nanotoxicology, Molecular and Integrative Physiological Sciences Program, Department of Environmental Health ...
Watson CY +5 more
doaj +1 more source
Preparation of Zoledronate liposome and its impact on apoptosis of Kupffer cells in rat liver [PDF]
Purpose: To establish a method for the preparation of zoledronate liposome and to observe its effect on inducing the apoptosis of rat liver Kupffer cells.
Qiao-Hong Zhao +7 more
doaj +1 more source
We have previously shown trichloroethylene (TCE) induced immune liver injury, and TNF-α/TNFR1 pathway as a probably mechanism underlying the immune damage, but the pathogenic mechanism is still unclear. The study aims to investigate whether TNF-α and its
Jia-xiang Zhang +7 more
doaj +1 more source
Elucidating Spatially-Resolved Changes in Host Signaling During Plasmodium Liver-Stage Infection
Upon transmission to the human host, Plasmodium sporozoites exit the skin, are taken up by the blood stream, and then travel to the liver where they infect and significantly modify a single hepatocyte.
Elizabeth K. K. Glennon +9 more
doaj +1 more source
Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]
Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Schauer, R. +11 more
core +1 more source
This study reports on the identification of two Plasmodium GAPDH epitope peptides that are responsible for sporozoite–Kupffer cell interaction and act as antigens against malaria infection.
Sung-Jae Cha +2 more
doaj +1 more source
Kupffer cells are maintained via self-renewal in specific microenvironmental niches, primarily the liver sinusoidal endothelial cells (LSECs). In this study, we propagated tissue-resident macrophages (Mø) from mouse liver using mixed culture with hepatic
Sho Kohara, Kazushige Ogawa
doaj +1 more source
Kupffer cells and their function [PDF]
ABSTRACT— The intention of this review is to stress new information regarding the quite versatile functions of Kupffer cells. Although their main function is phagocytosis and defence of the liver against bacteria, endotoxaemia and viral infections, they also fulfil other important roles.
openaire +2 more sources

