Results 21 to 30 of about 43,659 (221)
Open Medicine, 2021 Perivascular epithelioid cell tumor (PEComa) is a mesenchymal tumor rarely described in the liver. Sonazoid is a new ultrasound contrast with both vascular and post-vascular phases due to the uptake of Kupffer cell.
Li Chen, Xu Jing-Yong, Liu Yuan
doaj +1 more source
Cross-activating invariant NKT cells and kupffer cells suppress cholestatic liver injury in a mouse model of biliary obstruction. [PDF]
PLoS ONE, 2013 Both Kupffer cells and invariant natural killer T (iNKT) cells suppress neutrophil-dependent liver injury in a mouse model of biliary obstruction. We hypothesize that these roles are interdependent and require iNKT cell-Kupffer cell cross-activation ...
Caroline C Duwaerts +4 more
doaj +1 more source
Preparation of Zoledronate liposome and its impact on apoptosis of Kupffer cells in rat liver [PDF]
Acta Cirúrgica Brasileira, 2018 Purpose: To establish a method for the preparation of zoledronate liposome and to observe its effect on inducing the apoptosis of rat liver Kupffer cells.
Qiao-Hong Zhao +7 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2022 We have previously shown trichloroethylene (TCE) induced immune liver injury, and TNF-α/TNFR1 pathway as a probably mechanism underlying the immune damage, but the pathogenic mechanism is still unclear. The study aims to investigate whether TNF-α and its
Jia-xiang Zhang +7 more
doaj +1 more source
Elucidating Spatially-Resolved Changes in Host Signaling During Plasmodium Liver-Stage Infection
Frontiers in Cellular and Infection Microbiology, 2022 Upon transmission to the human host, Plasmodium sporozoites exit the skin, are taken up by the blood stream, and then travel to the liver where they infect and significantly modify a single hepatocyte.
Elizabeth K. K. Glennon +9 more
doaj +1 more source
Biomedicines, 2022 Kupffer cells are maintained via self-renewal in specific microenvironmental niches, primarily the liver sinusoidal endothelial cells (LSECs). In this study, we propagated tissue-resident macrophages (Mø) from mouse liver using mixed culture with hepatic
Sho Kohara, Kazushige Ogawa
doaj +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2020 Background & Aims: Toll-like receptor 2 (TLR2) and TLR3 regulate hepatic immunity under pathological conditions, but their functions and potential drug targets in alcoholic liver disease (ALD) remain poorly understood.
Pingping Luo +11 more
doaj +1 more source
Kupffer cells and their function [PDF]
Liver, 1987 ABSTRACT— The intention of this review is to stress new information regarding the quite versatile functions of Kupffer cells. Although their main function is phagocytosis and defence of the liver against bacteria, endotoxaemia and viral infections, they also fulfil other important roles.
openaire +2 more sources
Life Science Alliance, 2018 This study reports on the identification of two Plasmodium GAPDH epitope peptides that are responsible for sporozoite–Kupffer cell interaction and act as antigens against malaria infection.
Sung-Jae Cha +2 more
doaj +1 more source
Functions of two distinct Kupffer cells in the liver
Exploration of Medicine, 2021 Tissue-resident macrophages play critically important roles in host homeostasis and pathogenesis of diseases, with the functions of phagocytosis, metabolism, and immune modulation.
Chunye Zhang, Shuai Liu, Ming Yang
doaj +1 more source