Results 31 to 40 of about 46,673 (194)

Kupffer cells in hepatotoxicity

EXCLI journal, 2020
EXCLI Journal; 19:Doc1156; ISSN 1611 ...
openaire   +3 more sources

Hepatocyte Modulation of Kupffer Cell Prostaglandin E2 Production In Vitro [PDF]

, 1990
It is likely that dynamic interactions between hepatocytes and Kupffer cells contribute to the responses of these cell types both under normal conditions and during sepsis.
G W Machiedo, R L Simmons, B G Bentz, T W Lysz, T R Billiar, R D Curran   +5 more
core   +1 more source

Monocyte-derived Kupffer cells dominate in the Kupffer cell pool during liver injury

Cell Reports, 2023
Summary: Healthy Kupffer cell (KC) pool is dominated by embryonic KCs (EmKCs), preserving liver homeostasis. How the KC pool varies upon injury remains unclear.
Weiyang Li, Yuanru Yang, Lin Yang, Na Chang, Liying Li   +4 more
doaj   +1 more source

Kupffer Cell Isolation for Nanoparticle Toxicity Testing [PDF]

, 2015
The large majority of in vitro nanotoxicological studies have used immortalized cell lines for their practicality. However, results from nanoparticle toxicity testing in immortalized cell lines or primary cells have shown discrepancies, highlighting the ...
Al-Jamal, Khuloud T, Bourgognon, Maxime, Klippstein Martin, Rebecca, Klippstein, Rebecca, Al-Jamal, Khuloud T.   +4 more
core   +1 more source

Demonstration of glucose-6-phosphate dehydrogenase in rat Kupffer cells by a newly-developed ultrastructural enzyme-cytochemistry

European Journal of Histochemistry, 2009
Although various tissue macrophages possess high glucose- 6-phosphate dehydrogenase (G6PD) activity, which is reported to be closely associated with their phagocytotic/bactericidal function, the fine subcellular localization of this enzyme in liver ...
S Matsubara, D Matsubara, T Ishibashi, T Takizawa   +3 more
doaj   +1 more source

Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X [PDF]

, 2010
Human adenoviruses from multiple species bind to coagulation factor X (FX), yet the importance of this interaction in adenovirus dissemination is unknown.
Angela C Bradshaw, Duffy, Margaret R., Andrew H. Baker, Lynda Coughlan, Coughlan Lynda, Baker Andrew H., van Rooijen, Nico, van Rooijen, N., Nicklin, Stuart A., Margaret R Duffy, Parker, A.L., Kahari, V.M., Alan L Parker, Kähäri Veli-Matti, Stuart A Nicklin, Nico van Rooijen, Andrew H Baker, Coughlan, L., Nicklin Stuart A., Coughlan, Lynda, Kahari, Veli-Matti, Duffy, M.R., Parker Alan L., Bradshaw Angela C., Parker, Alan L., Duffy Margaret R., Bradshaw, Angela C., Bradshaw, A.C., Rooijen, N. van, Veli-Matti Kähäri, Angela C. Bradshaw, Alan L. Parker, Margaret R. Duffy, Stuart A. Nicklin, Baker, Andrew H., Baker, A.H., Nicklin, S.A., van Rooijen Nico   +37 more
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Kupffer cell present exogenous but not endogenous antigen to NKT cell. [PDF]

, 2013
Kupffer cells and hepatocytes were isolated from wild-type mice. (A) Representative histogram of Kupffer cell CD1d expression. Green line indicates staining with isotype control.
Min Lian (36697), Zhiping Li (95072), Yongheng Sui (492280), Jing Hua (198347), Tongfang Tang (492279)   +4 more
core   +1 more source

Quantification and regulation of apolipoprotein E expression in rat Kupffer cells.

Journal of Lipid Research, 1989
Apolipoprotein E (apoE) is synthesized by a wide variety of cells including cells of the monocyte-macrophage lineage. In order to assess the quantitative significance of apoE synthesis in a mature tissue macrophage, apoE synthesis was compared in Kupffer
P A Dawson, L M Lukaszewski, P F Ells, C C Malbon, D L Williams   +4 more
doaj   +1 more source

Kupffer cell activation is a causal factor for hepatic insulin resistance [PDF]

, 2010
Lanthier N, Molendi-Coste O, Horsmans Y, van Rooijen N, Cani PD, Leclercq IA. Kupffer cell activation is a causal factor for hepatic insulin resistance. Am J Physiol Gastrointest Liver Physiol 298: G107-G116, 2010.
Horsmans, Y., Cani, P.D., Molendi-Coste, O., Lanthier, Nicolas, Molendi-Coste, Olivier, Leclercq, Isabelle, Leclercq, I.A., Horsmans, Yves, van Rooijen, Nico, Cani, Patrice D., van Rooijen, N., Lanthier, N.   +11 more
core   +1 more source

Involvement of the TNF and FasL produced by CD11b Kupffer cells/macrophages in CCl4-induced acute hepatic injury. [PDF]

PLoS ONE, 2014
We previously reported that F4/80(+) Kupffer cells are subclassified into CD68(+) Kupffer cells with phagocytic and ROS producing capacity, and CD11b(+) Kupffer cells with cytokine-producing capacity. Carbon tetrachloride (CCl4)-induced hepatic injury is
Atsushi Sato, Hiroyuki Nakashima, Masahiro Nakashima, Masami Ikarashi, Kiyoshi Nishiyama, Manabu Kinoshita, Shuhji Seki   +6 more
doaj   +1 more source