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Kynurenic acid, a metabolite of the kynurenine pathway of tryptophan catabolism, acts as an antagonist for both the α7 nicotinic acetylcholine receptor and glycine coagonist sites of the N-methyl-d-aspartic acid receptor at endogenous brain ...
Tsutomu Fukuwatari
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Kynurenic acid is an endogenous product of the tryptophan metabolism, and as a broad-spectrum antagonist of excitatory amino acid receptors may serve as a protective agent in neurological disorders. The use of kynurenic acid as a neuroprotective agent is
József Toldi +2 more
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Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation
The role of tryptophan-kynurenine metabolism in psychiatric disease is well established, but remains less explored in peripheral tissues. Exercise training activates kynurenine biotransformation in skeletal muscle, which protects from neuroinflammation ...
Duarte Miguel Sacramento Ferreira +2 more
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Kynurenic Acid Concentrations Are Reduced in Huntington's Disease Cerebral Cortex
Journal of the Neurological Sciences, 1992M Flint Beal, Edward D Bird, W R Matson
exaly
Micromolar Concentration of Kynurenic Acid in Rat Small Intestine
Amino Acids, 2008Waldemar A. Turski +1 more
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Kynurenic Acid in the Digestive System–-New Facts, New Challenges
International Journal of Tryptophan Research, 2013Monika Turska +2 more
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Excitatory Amino Acid Receptor Antagonist Kynurenic Acid Attenuates Rewarding Potential of Morphine
European Journal of Pharmacology, 1994Edwin Zvartau, Anton Bespalov
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