Screening marine natural products for selective inhibitors of key kynurenine pathway enzymes [PDF]
Yunjiang Feng+2 more
openalex +1 more source
Kynurenine monooxygenase, a vital rate-limiting enzyme in the kynurenine pathway metabolic branch, has shown promise as a drug target for treating human neurodegenerative diseases.
Bai Li+11 more
doaj +1 more source
Depressive disorder is a severe mental condition. In addition to genetic factors, immunological-inflammatory factors, oxidative stress, and disturbances in neurotransmitter metabolism, kynurenine and serotonin pathways may play a role.
Lucia Ilavská+7 more
doaj +1 more source
Kynurenine pathway metabolism in human blood–brain–barrier cells: implications for immune tolerance & neurotoxicity [PDF]
R Owe‐Young+8 more
openalex +1 more source
NAD Biosynthesis Evolution in Bacteria: Lateral Gene Transfer of Kynurenine Pathway in Xanthomonadales and Flavobacteriales [PDF]
Wanessa C Lima+2 more
openalex +1 more source
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition. [PDF]
For nearly a century developmental biologists have recognized that cells from embryos can differ in their potential to differentiate into distinct cell types.
Battle, Stephanie L+26 more
core
Genetic and Environmental Impacts in Major Depressive Disorder are Mediated Via Kynurenine Pathway of Tryptophan Metabolism [PDF]
Gregory F. Oxenkrug
openalex +1 more source
Cortical Kynurenine Pathway Metabolism: A Novel Target for Cognitive Enhancement in Schizophrenia [PDF]
Ikwunga Wonodi, Robert Schwarcz
openalex +1 more source
Kynurenine pathway metabolites: relevant to vitamin B-6 deficiency and beyond [PDF]
Matthew A. Ciorba
openalex +1 more source
Evaluation of kynurenine pathway metabolism in Toxoplasma gondii-infected mice: Implications for schizophrenia [PDF]
Francesca M. Notarangelo+7 more
openalex +1 more source