Results 31 to 40 of about 14,286,973 (221)

Safety of l‐tryptophan technically pure, produced by Escherichia coli CGMCC 3667, for all animal species based on a dossier submitted by GBT Europe GmbH

open access: yesEFSA Journal, 2017
l‐Tryptophan, technically pure, is a feed additive produced by fermentation with a genetically modified strain of Escherichia coli. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) of EFSA, issued two opinions on the safety ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +24 more
doaj   +1 more source

Tryptophan transport in human fibroblast cells : a functional characterization

open access: yes, 2011
There are indications that serotonergic neurotransmission is disturbed in several psychiatric disorders. One explanation may be disturbed transport of tryptophan (precursor for serotonin synthesis) across cell membranes.
Lewander, Tommy   +11 more
core   +1 more source

D-, L- and D,L-Tryptophan-Based Polyamidoamino Acids: pH-Dependent Structuring and Fluorescent Properties [PDF]

open access: yes, 2019
Chiral polyamidoamino acids were obtained by polyaddition of N,N’methylenebisacrylamide with D-, D,L- and L-tryptophan (M-D-Trp, M-D,L-Trp and M-L-Trp). L-tryptophan/glycine copolymers, M-G-L-Trp5, M-G-L-Trp10, M-G-L-Trp20 and M-G-L-Trp40, were prepared ...
Federica Lazzari   +17 more
core   +1 more source

L-Tryptophan-Dependent Auxin-Producing Plant-Growth-Promoting Bacteria Improve Seed Yield and Quality of Carrot by Altering the Umbel Order

open access: yesHorticulturae, 2023
Carrot (Daucus carota L.) seed quality is affected by umbel position due to uneven maturation of carrot seeds produced in different umbel orders. However, keeping this in view, we tested whether seed quality could be improved with the suppression of ...
Anam Noor   +9 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Tryptophan depletion increases nausea, headache and photophobia in migraine sufferers [PDF]

open access: yes, 2006
Sensitivity to light was investigated 5 and 8 h after consumption of an amino acid drink which contained L-tryptophan (balanced amino acid condition: 19 controls and 22 migraine sufferers) or which produced a short-term reduction in brain serotonin ...
Drummond, P.D.
core  

Intestinal transport of tryptophan and its derivatives

open access: yes, 1964
The intestinal transport of l- and d-isomers of tryptophan and ten derivatives were studied in everted intestinal sacs of golden hamsters. It was found that l-tryptophan, 4-CH3-, 5-CH3-, and 6-CH3-dl-tryptophan, and N-chloroacetyl-l-tryptophan were ...
Linda L. Cohen, K. C. Huang
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

EFFECTS OF α-METHYL-DL-TRYPTOPHAN ON THE OXIDATION OF TRYPTOPHAN

open access: yes, 1955
α-Methyl-DL-tryptophan (AMT) inhibits the oxidation of DL-tryptophan by isotonic suspensions of rat liver, and the oxidation of L-tryptophan, L-tyrosine, DL-phenylalanine, and DL-methionine by cobra venom. The oxidation of L-tryptophan is accompanied by
T. L. Sourkes, Edith Townsend
core   +1 more source

Safety and efficacy of l‐tryptophan produced by fermentation with Escherichia coli CGMCC 7.248 for all animal species

open access: yesEFSA Journal, 2019
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on l‐tryptophan produced by fermentation with a genetically modified strain of ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +27 more
doaj   +1 more source

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