Advanced Science, EarlyView.A bioactive adhesive hydrogel capable of long‐term uterine retention (>14 days) and local microenvironment modulation is developed by straightforward integration of α‐lipoic acid, L‐arginine, tannic acid, and Lactobacillus johnsonii, which can markedly enhance endometrial repair and restore fertility in a rat model of endometrial injury.
Lifa Chen +9 more
wiley +1 more source
Eco-friendly and efficient synthesis of 1,4-dihydropyridines using a recyclable L-arginine-modified magnetic natural phosphate nanocatalyst. [PDF]
Sci RepRahimi M, Lasemi Z, Zeeb M.
europepmc +1 more source
Advanced Science, EarlyView.MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo +6 more
wiley +1 more source
Anti-fibrillation and trans-fibrillation activities of L-arginine modified magnetic nanoparticles on lysozyme. [PDF]
Biochem Biophys RepAlimohammadi V +5 more
europepmc +1 more source
TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
Advanced Science, EarlyView.A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
Comparison of the Safety and Efficacy of Oral L-arginine for the Treatment of Cognitive Impairment in Older Adults: A Prospective, Randomized, Placebo-Controlled Pilot Study. [PDF]
CureusTeotia S, Rana AK, Gupta V.
europepmc +1 more source
Advanced Science, EarlyView.Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He +10 more
wiley +1 more source
A Nutraceutical Approach for Hypertension: Randomized Controlled Trial of Grape Pomace Extract and L-Arginine. [PDF]
Antioxidants (Basel)Abate F +9 more
europepmc +1 more source
Advanced Science, EarlyView.This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun +7 more
wiley +1 more source
Role of L-Arginine in the Gut-Liver Axis of Female Mice: Mediating Ethanol's Alterations in Hepatic Steatosis and Oxidative Stress. [PDF]
Antioxidants (Basel)Daff K +7 more
europepmc +1 more source