Results 111 to 120 of about 22,679 (205)
Small Structures, Volume 7, Issue 3, March 2026.Armed with unique structural and functional properties, elastin‐like polypeptides attract their attentions as programmable materials in biomedical applications, including fusion tags for protein and nucleic acid purification; nanocarriers for protein, chemotherapeutics, and imaging agent delivery; hydrogels for tissue regeneration, 3D model ...
Yang Yuan +9 more
wiley +1 more source
Phase 1 Dose Escalation of Single‐Agent Mechlorethamine in Dogs With Lymphoma
Veterinary and Comparative Oncology, Volume 24, Issue 1, Page 51-57, March 2026.ABSTRACT Mechlorethamine is commonly prescribed to dogs at 3 mg/m2. The minimal toxicity observed indicates that higher doses of mechlorethamine are likely tolerable. The primary objective of this study was to determine the maximally tolerated dose (MTD) of mechlorethamine in dogs with lymphoma.
Laura E. Chadsey +2 more
wiley +1 more source
Revista Brasileira de Hematologia e HemoterapiaBackground l-Asparaginase is essential in the treatment of childhood acute lymphoblastic leukemia. If immunoglobulin G anti-l-asparaginase antibodies develop, they can lead to faster plasma clearance and reduced efficiency as well as to hypersensitivity
Gabriela Galindo-Rodríguez +8 more
doaj +1 more source
Diverse origins of microbial L-asparaginases and their current miscellaneous applications
Archives of Pharmaceutical Sciences Ain Shams University, 2019 L-asparaginase, also known as amidohydrolase, catalyzes the breakdown of asparagine into aspartic acid and ammonia. Due to its ability to inhibit the biosynthesis of protein lymphoblasts, it is used to treat acute lymphoblastic leukemia (ALL).
Nada A. Abdelrazek +3 more
doaj +1 more source
L-asparaginase-antileukemia agent.
JPMA. The Journal of the Pakistan Medical Association, 1977 This paper is an extension of a previous report (Yaqub 1975). Our interest in L-asparaginase is increasing due to the recognition of the fact that it is a best tool against leukemia. In this paper we have tried to discuss (in view of research work, 1973-75) its basic characteristics and its practicability of successfully being used as an antitumour ...
A, Jabbar, M, Yaqub
openaire +2 more sources
Kloniranje, funkcionalna ekspresija i karakterizacija L-asparaginaze II iz E. coli MTCC 739 [PDF]
, 2011 L-Asparaginase is an antineoplastic agent that selectively decreases the level of L-asparagine in blood and diminishes the proliferation of the cancerous cells.
Ashok Pandey +3 more
core +1 more source
, 2019 Biosensors are rising technologies in the pharmaceutical field for medicine discovery, development and Quality Control (QC) stages. Surface acoustic wave (SAW) biosensor employs acoustic waves generated by oscillating a piezoelectric crystal quartz plate
De Spiegeleer, Bart +4 more
core +1 more source
Chemosensitizing effect of apigenin on T-ALL cell therapy
Frontiers in PharmacologyT-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy with limited therapeutic options and frequent treatment-associated toxicities.
Nigar Huseynova +4 more
doaj +1 more source
Synthesis Optimization of L-Aspartic acid β-hydroxamate by a novel Enzyme, β-Aspartyl-γ-glutamyl transferase [PDF]
, 2015 L-Aspartic acid β-hydroxamate or L-β-Aspartyl hydroxamate (BAH), water soluble- chemical compound currently obtains popularity due to its role in several important biochemical processes and to its bioactivities.
Naohara, Ryosuke +4 more
core
Journal of the Egyptian National Cancer InstituteBackground Recent statistical analyses indicate a rapid increase in the incidence of breast and colon cancer in Egypt. Although invasive techniques have been widely employed for early detection, diagnosis, and intervention of those cancers, they are ...
Dina Johar +5 more
doaj +1 more source