Results 201 to 210 of about 15,313,595 (281)

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Genetic profiles and hematological characteristics of the α-Hb variant Hb Chumphae (HBA2:c.32T>A) in association with -^SEA deletion α⁰-thalassemia. [PDF]

Hematol Transfus Cell Ther
Sihathip P, Srisuwan W, Sumphanapai T, Satthakarn S, Ngokwongs T, Panyasai S.   +5 more
europepmc   +1 more source

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, EarlyView.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source

N-Acetyl Aspartic Acid (NAA) Attenuates Stemness and Epithelial-Mesenchymal Transition and Enhances Radio- and Chemo-Sensitivity in Pancreatic Ductal Adenocarcinoma. [PDF]

Cells
Crispo F, Lioy R, Dieli R, Martinelli M, Calabrese C, Bianculli A, De Fina V, Lazzari G, Metallo V, Telesca D, Laus G, Loperte S, Lerose R, Mazzoccoli C.   +13 more
europepmc   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Effects of Exogenous Monosodium Glutamate on GABA Accumulation and Volatile/Nonvolatile Metabolites in Black Highland Barley. [PDF]

Food Sci Nutr
Lu X, Ma N, Wang Y.
europepmc   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Carbonized polymer dots with aqueous‐stable room‐temperature phosphorescence: Mechanism, matrix engineering, and application

Responsive Materials, EarlyView.
This review focuses on inorganic and organic matrices that enable aqueous‐stable room‐temperature phosphorescence (RTP) in carbonized polymer dots (CPDs). It explains the underlying RTP mechanisms, highlights how matrix engineering provides spatial confinement and bonding interactions to stabilize triplet excitons in water, and demonstrates key ...
Yuhan Hou, Chengyu Zheng, Songyuan Tao, Yuzhuo Wang, Bai Yang   +4 more
wiley   +1 more source

<i>In vitro</i> and <i>in vivo</i> activity of the aspartic protease inhibitor CWHM-117 against <i>Toxoplasma gondii</i>. [PDF]

Antimicrob Agents Chemother
Santos GPd, Dias IdO, Koley S, Meyers MJ, Reimão JQ.   +4 more
europepmc   +1 more source

Thermosensitive Nanostructured Coacervates Developed by Mixing ABA‐ and AB‐Block Copolymers and Their Unique Sustained Release of Nano‐Micelles in a Regulated Manner

Small, EarlyView.
Polyion complex micelles composed of blends of ABA and AB block copolymers can form coacervates with a hexagonally packed cylinder nanostructure after heating. The resulting coacervates can release the micelles under physiological conditions in a zero‐order kinetics, possessing cargo proteins.
Takumi Egashira, Hiroshi Kamizawa, Yujiro Hamada, Wataru Fushimoto, Hiroshi Y. Yoshikawa, Yuji Higaki, Atsushi Takahara, Takeshi Mori, Yoshiki Katayama, Akihiro Kishimura   +9 more
wiley   +1 more source