Results 41 to 50 of about 1,567,546 (339)
, 2020 Sem informaçãoA mother crystal formed from a transient molecular structure of (D+L) aspartic acid in solution is reported. Hexagonal structures with a lattice constant of 1.04 nm were crystallized from a solution in which three aspartic acid species ...
Teschke, O., Soares, D. M.
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Changes of Metabolites and Related Flavors in Mandarin Fish (Siniperca chuatsi) during 24 h of Refrigeration [PDF]
Shipin KexueThe study aimed to investigate the changes of metabolites and related flavors in the muscle of fresh mandarin fish (Siniperca chuatsi) during 24 h of postmortem refrigeration at 4 ℃ by ultra performance liquid chromatography coupled with high resolution ...
ZHOU Beibei, WU Minglin, JIANG Yangyang, SUN Yongxu, LI Haiyang, CUI Kai
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Biosynthesis of N-Acetyl-l-aspartic Acid
Journal of Biological Chemistry, 1959 (Received for publication, May 11, 1959) The occurrence of N-acetyl+aspartic acid in mammalian and avian brain at concentrations from 80 to 120 mg per 100 g fresh weight of tissue was demonstrated recently by Tallan et al. (1). The pattern of distribution of acetylaspartic acid in bovine brain was found by Tallan (2) to parallel that of many enzymes ...
openaire +2 more sources
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
BiomoleculesMyocardial infarction (MI), including ST-segment elevation MI (STEMI) and non-ST-segment elevation MI (NSTEMI), is still a leading cause of death worldwide.
Jie Zhou +8 more
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International Journal of Electrochemical Science, 2011 The electrochemical behaviors of Epinephrine (EP) on a poly(l-aspartic acid) membrane are studied by cyclic voltammetry and electrochemical impedance spectroscopy (EIS).
YU Zhang-yu +4 more
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Comprehensive evaluation of caloric restriction-induced changes in the metabolome profile of mice
Nutrition & Metabolism, 2022 Objects Caloric restriction (CR) is known to extend lifespan and exert a protective effect on organs, and is thus a low-cost and easily implemented approach to the health maintenance. However, there have been no studies that have systematically evaluated
Dadi Xie +11 more
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Towards the directed evolution of an L-aspartate oxidase from Pseudomonas putida [PDF]
, 2012 Amino acid oxidases (AAOs) are enantioselective flavoenzymes that catalyse the oxidation of amino acids into imino acids, which spontaneously hydrolyse in water to form keto acids. AAOs have several potential applications, most notably as biocatalysts in
Leese, Charlotte
core
, 1994 L-Aspartic acid by successive N-tosylation, anhydride formation, and reduction was converted into (3S)-3-(tosylamino)butano-4-lactone (4). Electrophilic methylation of 4, subsequent iodo-esterification and nucleophilic methylation, followed by ...
Jefford, Charles +3 more
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