Results 41 to 50 of about 15,313,595 (281)
BiomoleculesMyocardial infarction (MI), including ST-segment elevation MI (STEMI) and non-ST-segment elevation MI (NSTEMI), is still a leading cause of death worldwide.
Jie Zhou +8 more
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International Journal of Electrochemical Science, 2011 The electrochemical behaviors of Epinephrine (EP) on a poly(l-aspartic acid) membrane are studied by cyclic voltammetry and electrochemical impedance spectroscopy (EIS).
YU Zhang-yu +4 more
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GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Comprehensive evaluation of caloric restriction-induced changes in the metabolome profile of mice
Nutrition & Metabolism, 2022 Objects Caloric restriction (CR) is known to extend lifespan and exert a protective effect on organs, and is thus a low-cost and easily implemented approach to the health maintenance. However, there have been no studies that have systematically evaluated
Dadi Xie +11 more
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Threonine 348 regulates the subcellular localization of PTEN
FEBS Open Bio, EarlyView.Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
Biosynthesis of N-Acetyl-l-aspartic Acid
Journal of Biological Chemistry, 1959 (Received for publication, May 11, 1959) The occurrence of N-acetyl+aspartic acid in mammalian and avian brain at concentrations from 80 to 120 mg per 100 g fresh weight of tissue was demonstrated recently by Tallan et al. (1). The pattern of distribution of acetylaspartic acid in bovine brain was found by Tallan (2) to parallel that of many enzymes ...
openaire +2 more sources
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
The Key Metabolites in Rice Quality Formation of Conventional japonica Varieties
Current Issues in Molecular Biology, 2023 To understand differences in the quality of different conventional japonica rice varieties and variations in metabolites related to rice quality, the quality of three conventional japonica varieties was determined, and the metabolites of the milled rice ...
Qiangqiang Xiong +6 more
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Bio‐Inspired Synthesis of Macroporous Single Crystal Particles as Scattering Agents
Advanced Functional Materials, EarlyView.A general strategy is presented that delivers unique, single‐crystal microparticles that combine submicron macroporosity and uniform particle shapes. A bioinspired approach is used to occlude three distinct types of additives – polystyrene microspheres, polymer vesicles and amino acids – within calcite single crystals, and subsequent thermal annealing ...
Stephanie E. Foster +11 more
wiley +1 more source
A novel injectable and self-biodegradable poly(aspartic acid) hydrogel
Materials & Design, 2023 Severely chronic dermal wounds with irregular rupture shapes or even cavities are calling for injectable and self-biodegradable wound dressings for skin lesion with complex contours remain a great challenge.
Kuan Yang +9 more
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