Results 51 to 60 of about 179,087 (303)

A novel injectable and self-biodegradable poly(aspartic acid) hydrogel

Materials & Design, 2023
Severely chronic dermal wounds with irregular rupture shapes or even cavities are calling for injectable and self-biodegradable wound dressings for skin lesion with complex contours remain a great challenge.
Kuan Yang, Xinyi Zhao, Wei Wei, Chen Xuan Lin, Lei Sun, Zhao Wei, Qiang Huang, Xing Ge, Miklós Zrínyi, Yong Mei Chen   +9 more
doaj   +1 more source

PREPARATION OF L-ASPARTIC ACID BY BACTERIAL ASPARTASE

The Journal of General and Applied Microbiology, 1959
(1) 強力なアスパーターゼを持つことが知られている二,三の菌種と当研究所保存の菌種,合わせて30余株からアスパーターゼの最も強力と思われたEscherichia coli No. 2を選び,アスパーターゼの若干の性質を検討した. (2) アスパーターゼはフマール酸ソーダ塩及びアンモニウム塩の飽和溶液(各々遊離酸として前者約10%,後着約20%)に於ても反応させ得ることが分り,更に50g/100m1ものフマール酸アンモニウム懸濁液に, E. coli No. 2の乾燥菌体を添加, 37°, pH7.2～7.4にて攪拌を続け1乃至3日間に,フマール酸をほぼ定量的にL-アスパラギン酸に変えることが出来た.
Kakuo KITAHARA, Sakuzo FUKUI, Masanaru MISAWA   +2 more
openaire   +3 more sources

Synthesis of beta-lactam peptidomimetics through Ugi MCR: first application of chiral N-beta-Fmoc amino alkyl isonitriles in MCRs [PDF]

, 2011
Chiral N-beta-Fmoc amino alkyl isonitriles were employed in Ugi multi component reactions (Ugi 4C-3CR) to obtain functionalized beta-lactam peptidomimetics with L-aspartic acid alpha-methyl ester/peptide ester and organic aldehydes.
Narendra, N., Sureshbabu, V.V., Vishwanatha, T.M.   +2 more
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Intraspecfic variation in cold-temperature metabolic phenotypes of Arabidopsis lyrata ssp petraea [PDF]

, 2009
Atmospheric temperature is a key factor in determining the distribution of a plant species. Alongside this, plant populations growing at the margin of their range may exhibit traits that indicate genetic differentiation and adaptation to their local ...
A Suzuki, AB Bleeckerl, B Jonsell, B Usadel, B Vinocur, BH Miesak, C Alonso-Blanco, CD Thomas, CL Guy, D Cook, F Kaplan, F Kaplan, F. Ian Woodward, GR Gray, GR Walther, GR Walther, HM Lam, HM Lam, HM Lam, IC Oliveira, J Kilian, J Klotke, L Skøt, M Stitt, MA Hannah, Matthew P. Davey, MF Thomashow, MJ Clauss, MJ Clauss, MP Davey, N Smirnoff, NR Sackville Hamilton, OK Atkin, P Vergeer, RC Meyer, RJ Li, S Sagisaka, TK Peterman, W. Paul Quick, Y Zhen, Å Strand   +40 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Liquid Phase Transmission Electron Microscopy: A Window into the Early Stages of Complex Material Formation

Advanced Functional Materials, EarlyView.
Liquid‐phase transmission electron microscopy enables direct observation of nucleation and growth processes in solution. This review is dedicated to the remembrance of Helmut Cölfen and highlights recent studies on complex materials—oxides, biominerals, organic–inorganic crystals—which were central to his research activity. It summarizes key milestones,
Charles Sidhoum, Vinavadini Ramnarain, Nathaly Ortiz Peña, Dris Ihiawakrim, Clément Sanchez, Ovidiu Ersen   +5 more
wiley   +1 more source

Insights into the Flavor Differentiation between Two Wild Edible Boletus Species through Metabolomic and Transcriptomic Analyses

Foods, 2023
Despite the popularity of wild edible mushrooms due to their delectable flavor and nutritional value, the mechanisms involved in regulating and altering their taste remain underexplored.
Kaixiang Chao, Tuo Qi, Qionglian Wan, Tao Li   +3 more
doaj   +1 more source

Study of the Cys-His bridge electron transfer pathway in a copper-containing nitrite reductase by site-directed mutagenesis, spectroscopic, and computational methods [PDF]

, 2018
The Cys-His bridge as electron transfer conduit in the enzymatic catalysis of nitrite to nitric oxide by nitrite reductase from Sinorhizobium meliloti 2011 (SmNir) was evaluated by site-directed mutagenesis, steady state kinetic studies, UV-vis and EPR ...
Brondino, Carlos Dante, Cristaldi, Julio César, Dalosto, Sergio Daniel, Ferroni, Felix Martín, González, Pablo Javier, Gómez, María C., Rivas, Maria Gabriela, Rizzi, Alberto Claudio   +7 more
core   +1 more source

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source