Results 211 to 220 of about 73,863 (280)

The multifaceted roles of the ACSL family in cancer: Metabolic reprogramming, ferroptosis regulation and tumour immune microenvironment remodelling

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
The acyl‐CoA synthetase long‐chain (ACSL) family consists of five members, which exhibit a synergistic effect in promoting tumour lipid metabolism for energy supply. Specifically, ACSL3 and ACSL4 have antagonistic effects on the mechanisms related to ferroptosis in tumour cells.
Haocai Li, Weijian Wang, Juncheng Zhan, Yuxiang Xiao, Xiaoping Chen, Chen Su, Peng Zhu   +6 more
wiley   +1 more source

Impact of varying L-carnitine doses on the motility and activation parameters of bull sperm <i>in vitro</i> during low-motile sperm cryopreservation. [PDF]

Open Vet J
Al-Ebady AS.
europepmc   +1 more source

Renal Protection at a Metabolic Cost: A Systematic Review and Meta‐Analysis of Perioperative Use of Sodium–Glucose Cotransporter 2 Inhibitors

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
Across 246,542 surgical patients, perioperative SGLT2 inhibitor use was associated with a lower odds of acute kidney injury and mortality. In contrast, ketoacidosis outcomes (DKA and euglycemic ketoacidosis) showed no statistically significant difference overall, but appeared more frequent in selected sensitivity and subgroup analyses, consistent with ...
Elsayed Balbaa, Ahmed Farid Gadelmawla, Ahmed Ibrahim, AlMothana Manasrah, Ahmed Elbataa, Abdalhakim Shubietah, Mohamed S. Elgendy, Ahmed Sobhy, Ahmed Mansour, Ameer Awashra, Nourhan N. Elguindy, Mohammad Bazzazeh, Abdelhamid Ben‐Selma   +12 more
wiley   +1 more source

Unlocking Relief: Investigating the Impact of a Fixed Combination of Acetyl-L-Carnitine and Palmitoylethanolamide on Traumatic Acute Low Back Pain. [PDF]

Eur J Neurol
Cominacini M, Valenti MT, Braggio M, Caramori A, Vedovi E, Dalle Carbonare L.   +5 more
europepmc   +1 more source

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

Food Frontiers, Volume 7, Issue 2, March 2026.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li, Qihui Zhu, Yang Li, Haiyu Zhao, Yi Bi, Chuanying Pan, Min Wang, Lin Han, Xianyong Lan   +8 more
wiley   +1 more source

Diagnosis of deep vein thrombosis from γ-butylbetaine and L-carnitine in plasma and urine based on untargeted and targeted metabolomics. [PDF]

Sci Rep
Zeng W, Wang Q, Li X, Wang Z, Chi J, Yang Z, Li J, Gao YY, Qu M.   +8 more
europepmc   +1 more source

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source

Intermittent ischemia/reperfusion as a potent insulin-sensitizing intervention via blood flow enhancement and muscle decanoyl-l-carnitine suppression. [PDF]

J Clin Invest
Kido K, Hingst JR, Onslev J, Sjøberg KA, Birk JB, Eskesen NO, Zhou T, Kawanaka K, Havelund JF, Færgeman NJ, Hellsten Y, Wojtaszewski JF, Kjøbsted R.   +12 more
europepmc   +1 more source

Human Milk–Derived Peptide MAMP‐1 Ameliorates Sepsis‐Associated Acute Lung Injury in Mice Through APOA4 and the TLR4/NF‐κB Signaling Pathway

Food Frontiers, Volume 7, Issue 2, March 2026.
The study found that MAMP‐1 can alleviate lung injury by modulating the TLR4 signaling pathway to suppress LPS‐induced inflammation and promote cholesterol reverse transport. ABSTRACT Sepsis‐associated acute lung injury (SALI) significantly jeopardizes the health and survival prospects of neonates.
Shimei Lu, Rui Long, Yanmin Li, Fengqiong Tan, Xiaoguang He, Tengfei Wang, Xingyun Wang, Fengdan Xu, Ning Li   +8 more
wiley   +1 more source

Antiviral and virucidal activities against SARS-CoV-2 and antibacterial properties of bile acids and their salts with naturally occurring organic cations of l-carnitine, creatinine, and choline. [PDF]

RSC Adv
Varongkriengkrai C, Chutiwitoonchai N, Leerach N, Sureram S, Pooprasert T, Aree T, Khoomrung S, Mahidol C, Ruchirawat S, Kittakoop P.   +9 more
europepmc   +1 more source