Results 141 to 150 of about 13,200,542 (201)

Carnosine-Related Metabolism in Rat Cardiomyocytes and Human Heart Tissue. [PDF]

FASEB J
Creighton JV, de Souza Gonçalves L, Gil S, Vargas BS, Jensen L, de Medeiros MHG, Roschel H, Turner MD, Doig CL, Artioli GG, Sale C.   +10 more
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Carnosinylation of Cardiac Antigens Attenuates Immunogenic Responses and Improves Function in Failing Hearts. [PDF]

J Am Heart Assoc
Doelling B, Chaudhari M, Hoetker D, Brittian K, Nong Y, Stephan JK, Jouja I, Janis HI, Mitchell T, Wysoczynski M, Bhatnagar A, Jones SP, Baba SP.   +12 more
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Identification and characterization of a mouse dipeptidase that hydrolyzes L-carnosine

Identification and characterization of a mouse dipeptidase that hydrolyzes L-carnosine
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An assessment of the transport mechanism and intraneuronal stability of l-carnosine

Amino Acids, 2021
L-Carnosine (β-alanyl-L-histidine) is a well-known antioxidant and neuroprotector in various models on animals and cell cultures. However, while there is a plethora of data demonstrating its efficiency as a neuroprotector, there is a distinct lack of data regarding the mechanism of its take up by neurons.
Alexander V. Lopachev, Denis A. Abaimov, Ivan S. Filimonov, Kseniya N. Kulichenkova, Tatiana N. Fedorova   +4 more
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Effect of L-carnosine on the intraocular pressure

Bulletin of Experimental Biology and Medicine, 1988
No data could be found in the literature on the influence of carnosine on effects produced by prostaglandins (PG). On instillation into the conjunctival sac or by subconjunctival injection, PG of the El, E2, and F2~ groups cause an acute rise of intraocular pressure (lOP) in laboratory animals; this prostaglandin-induced ocular hypertension arises as a
V. N. Ermakova, M. A. Babizhaev, A. Ya. Bunin   +2 more
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Synthesis of L-carnosine and its analogs

Bulletin of the Academy of Sciences, USSR Division of Chemical Science, 1966
A description is given of the synthesis of the dipeptides L-carnosine, N-4-aminobutyryl-L-histidine, and N-DL-alanyl-L-histidine from p-nitrophenyl esters of phthalimido acids and histidine methyl ester in over-all yields of about 40%, based on the histidine taken.
A. A. Glemzha, S. E. Severin
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The effects of l-Carnosine on development of metabolic syndrome in rats

Life Sciences, 2019
The prevalence of metabolic syndrome (MetS) is increasing in several countries. The MetS is characterized by the occurrence of at least three of the following risk factors: decreased high-density lipoprotein cholesterol, increased blood pressure, raised fasting blood glucose, elevated triglycerides, and abdominal obesity. There is a growing evidence of
Nour A, Al-Sawalha, Osama Y, Alshogran, Mofleh S, Awawdeh, Basima A, Almomani   +3 more
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Identification and Characterization of a Mouse Dipeptidase That Hydrolyzes l-Carnosine

Journal of Biochemistry, 2005
L-Carnosine is a bioactive dipeptide present in mammalian tissues including the central nervous system. We have recently shown that L-carnosine is involved in the regulation of energy homeostasis through the autonomic nervous system, but the mechanisms for its biosynthesis and degradation have not yet been fully elucidated.
Hiroto, Otani, Nobuaki, Okumura, Akiko, Hashida-Okumura, Katsuya, Nagai   +3 more
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Peptide transport in rabbit kidney. Studies with l-carnosine

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1982
L-Carnosine was shown to be transported into rabbit renal brush-border membrane vesicles by an Na+ -independent mechanism. The transport was competitively inhibited by glycyl-L-proline. Various di- and tripeptides inhibited L-carnosine transport, whereas free amino acids did not.
V, Ganapathy, F H, Leibach
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