Results 151 to 160 of about 13,200,542 (201)

Ocular Pharmacokinetic Study of l-Carnosine and N-Acetyl-l-carnosine in Rabbit by Microdialysis Coupled with UPLC-MS-MS

Chromatographia, 2011
In order to provide useful information for rational drug design, the ocular pharmacokinetics of l-carnosine (CAR) and its acetylized prodrug N-acetyl-l-carnosine (NAC) were investigated. The in vivo microdialysis sampling coupled with ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) was developed for continuously ...
Dan Su, Yonggui Song, Lulu Geng, Binbin Wei, Pu Xie, Yue Qi, Chao Ma, Shilin Yang, Kaishun Bi, Xiaohui Chen   +9 more
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A comparison of the cellular actions of polaprezinc (zinc-l-carnosine) and ZnCl2

Life Sciences, 2012
Zinc supplementation has been proven to be beneficial for the prevention of some health problems. Many zinc supplements are used for medical and nutritional purposes. However, it is difficult to distinguish between them in terms of their cellular actions.
Hakaru, Seo, Ikuko, Ogata-Ikeda, Shiro, Ishida, Yoshiro, Okano, Yasuo, Oyama   +4 more
openaire   +2 more sources

Synergistic Effect of L-Carnosine and EGCG in the Prevention of Physiological Brain Aging

Current Pharmaceutical Design, 2013
The benefits of multi-target action are well established in a variety of pathological models. Many dietary supplements and nutraceuticals may be useful to slow age-related cognitive declines and the risk of developing neurodegenerative disease. L-Carnosine and EGCG are natural compounds that have received particular attention because of their potential
DAVINELLI , SERGIO, DI MARCO, Roberto, BRACALE, Renata, Quattrone A, Zella D, SCAPAGNINI, Giovanni   +5 more
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Nα-Acetylcarnosine is a prodrug of L-carnosine in ophthalmic application as antioxidant

Clinica Chimica Acta, 1996
The naturally occurring compound N alpha-acetylcarnosine (NAC) is proposed as the prodrug of L-carnosine (C) resistant to enzymatic hydrolysis by human serum carnosinase. Rabbit eyes were treated with 1% NAC, C or placebo and extracts of the aqueous humor from the anterior eye chamber were analyzed for imidazole content by reverse phase analytical high
M A, Babizhayev, V N, Yermakova, N L, Sakina, R P, Evstigneeva, E A, Rozhkova, G A, Zheltukhina   +5 more
openaire   +2 more sources

Enthalpies of acid dissociation of l-carnosine in aqueous solution

Journal of Thermal Analysis and Calorimetry, 2019
The enthalpies of l-carnosine interaction with solutions of hydrochloric acid have been measured by calorimetric method in the presence of NaCl at 298.15 K and ionic strength as high as 0.25, 0.50 and 0.75 mol dm−3. The enthalpies of acid dissociation have been determined from the obtained data.
A. I. Lytkin, V. P. Barannikov, V. G. Badelin, O. N. Krutova   +3 more
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Effect of L-Carnosine on Children with ADHD

Indian Journal of Pediatrics, 2022
Debi Ann Abraham, Rajanandh Muhasaparur Ganesan   +1 more
openaire   +2 more sources

ChemInform Abstract: A SIMPLE AND EFFICIENT SYNTHESIS OF L‐CARNOSINE

Chemischer Informationsdienst, 1983
AbstractA Simple and Efficient Syntheses of L‐Carnosine.
F. J. VINICK, S. JUNG
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CHAPTER 21. l-Carnosine and Human Colon Cancer

2015
Colon cancer is a multifactorial disease, although diet and chronic inflammation are considered the main risk factors for developing this cancer. Treatment of colorectal cancer depends on the location, size, and extent of cancer spread, as well as the health of the patient.
Barbara Iovine, Mariangela Garofalo, Maria Orefice, Maria Assunta Bevilacqua   +3 more
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The Possible Roles of β-alanine and L-carnosine in Anti-aging

Current Medicinal Chemistry
β-alanine (BA), being a non-proteinogenic amino acid, is an important constituent of L-carnosine (LC), which is necessary for maintaining the muscle buffering capacity and preventing a loss of muscle mass associated with aging effects. BA is also very important for normal human metabolism due to the formation of a part of pantothenate, which
Gasmi, Amin, Mujawdiya, Pavan Kumar, Lysiuk, Roman, Shanaida, Mariia, Peana, Massimiliano, Piscopo, Salva, Beley, Nataliya, Dzyha, Svitlana, Smetanina, Kateryna, Shanaida, Volodymyr, Résimont, Stéphane, Bjørklund, Geir   +11 more
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Self-assembled structures of ferrocene-l-carnosine conjugates

Journal of Organometallic Chemistry, 2017
Abstract Ferrocene- l -carnosine conjugates, Fc- l -Carnosine-OEt and Fc 2 - l -Carnosine-OEt , were synthesized and characterized by X-ray crystallographic analyses. The single-crystal X-ray structure determination of Fc- l -Carnosine-OEt was demonstrated to reveal the formation of antiparallel β -sheet-like 12-membered ...
Toshiyuki Moriuchi, Taiki Nishiyama, Yoshiki Tayano, Norimitsu Tohnai, Toshikazu Hirao   +4 more
openaire   +1 more source