Results 91 to 100 of about 30,868 (223)

Ultrasonic‐assisted extraction of bioactive compounds from eggplant (Solanum melongena L.) calyx and evaluation of extract properties

JSFA reports, EarlyView.
Abstract Background Eggplant (Solanum melongena L.) is widely consumed worldwide and generates considerable waste, including peel and calyx, during processing and consumption. Although often considered as by‐products, these wastes are rich sources of bioactive compounds, which vary depending on the plant variety and cultivation location.
Neda Parvazi Qomi, Ghazal Labbeiki
wiley   +1 more source

Evaluation of anti-diarrhoeal activity of L-citrulline in mice [PDF]

, 2019
Background: L-citrulline is a naturally occurring physiological non-essential amino acid that plays an important role in the metabolism and regulation of nitric oxide.
Abdulwahab, A, Babale, A.I., Farra’u, U, Saleh, M.I.A., Saminu, S   +4 more
core   +2 more sources

A case report on the long‐term use of teduglutide in a pediatric patient with short bowel syndrome

Nutrition in Clinical Practice, EarlyView.
Abstract Short bowel syndrome (SBS) is the leading cause of intestinal failure, frequently necessitating long‐term parenteral nutrition (PN). Teduglutide (TED), a glucagon‐like peptide‐2 analog, has demonstrated efficacy in reducing PN dependence in both adults and children. However, long‐term data in pediatric populations remain limited.
Tsuyoshi Sakurai, Hironori Kudo, Nakamura Megumi, Ryo Ando, Takuro Kazama, Ryuji Okubo, Masatoshi Hashimoto, Ko Minoshima, Motoshi Wada   +8 more
wiley   +1 more source

Tumor cell membrane camouflaged liposomal pharmaceuticals for cascade catalysis‐driven redox modulation and synergistic ROS/RNS antitumor therapy

VIEW, EarlyView.
A tumor cell membrane camouflaged liposomal nanoplatform (C‐MLip@LA) modulates tumor redox homeostasis to enhance targeted therapy. By encapsulating L‐arginine, anchoring MnO2 nanoparticles, and leveraging homologous membrane‐mediated specificity, C‐MLip@LA efficiently triggers a synergistic ROS/RNS cascade, amplifies immunogenic cell death, and ...
Guangrong Zheng, Tengfei Ke, Hongjin Wang, Hong Huang, Ying Zhang, Guanghai Fei, Chengde Liao, Haiyan Yang   +7 more
wiley   +1 more source

Oral L-Citrulline Supplementation Improves Fatty Liver and Dyslipidemia in Adolescents with Abdominal Obesity: A Parallel, Double-Blind, Randomized Clinical Trial

Gastroenterology Insights
Obesity in adolescents is associated with non-communicable risk factors and diseases like metabolic-associated fatty liver disease (MAFLD), which is the liver manifestation of metabolic syndrome.
Verónica Ivette Tovar-Villegas, Yejin Kang, Lorena del Rocío Ibarra-Reynoso, Montserrat Olvera-Juárez, Armando Gomez-Ojeda, Víctor Manuel Bosquez-Mendoza, Miriam Lizette Maldonado-Ríos, Ma. Eugenia Garay-Sevilla, Arturo Figueroa   +8 more
doaj   +1 more source

Enteral Glutamine Administration in Critically Ill Nonseptic Patients Does Not Trigger Arginine Synthesis

Journal of Nutrition and Metabolism, 2016
Glutamine supplementation in specific groups of critically ill patients results in favourable clinical outcome. Enhancement of citrulline and arginine synthesis by glutamine could serve as a potential mechanism.
Mechteld A. R. Vermeulen, Saskia J. H. Brinkmann, Nikki Buijs, Albertus Beishuizen, Pierre M. Bet, Alexander P. J. Houdijk, Johannes B. van Goudoever, Paul A. M. van Leeuwen   +7 more
doaj   +1 more source

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Integrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu, Zhanjun Ren, Xiuzhu Sun, Shuhui Wang   +3 more
wiley   +1 more source

Identification of nitric oxide synthase in human and bovine oviduct [PDF]

, 2017
Nitric oxide synthase (NOS) is responsible for the biological production of nitric oxide (NO) in several organs. NOS activity has also been localized in the reproductive tract, although direct evidence for its presence in the human or bovine oviduct is ...
Dubey, R.K., Fink, D., Imthurn, B., Keller, P.J., Lauper, U., Macas, E., Rosselli, M., Rosselli, M.A.   +7 more
core  

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

The production and detoxification of a potent cytotoxin, nitric oxide, by pathogenic enteric bacteria [PDF]

, 2011
The nitrogen cycle is based on several redox reactions that are mainly accomplished by prokaryotic organisms, some archaea and a few eukaryotes, which use these reactions for assimilatory, dissimilatory or respiratory purposes.
Anke Arkenberg, Bleakley, Bodenmiller, Brunelli, Chakravortty, Cherayil, Constantinidou, Crawford, Cruz-Ramos, David J. Richardson, Filenko, Gardner, Gary Rowley, Gilberthorpe, Gilchrist, Husain, Justino, Mastroeni, Miller, Mills, Overton, Prior, Pullan, Ramotar, Richardson, Rodionov, Sebastian Runkel, Shiloh, Smith, Spiro, Todorovic, Tripathi, van Wonderen, Vine, Vine, Wang, Wink   +36 more
core   +1 more source