Results 141 to 150 of about 31,622 (258)

A Scalable Organoid Model of Urothelial Aging for Metabolic Interrogation, Infection Modeling, and Reversal of Age‐Associated Changes

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
mBEDOs: a scalable platform for modeling urothelial aging. mBEDOs derived from aged mouse bladders capture essential molecular and cellular features of urothelial aging and provide a versatile system for high‐throughput metabolic profiling, therapeutic screening via metabolite supplementation, age‐ and sex‐based analyses, infection modeling, and immune–
Adwaita R. Parab   +8 more
wiley   +1 more source

Alterations in Gut Microbiota and Metabolism in Cirrhotic Portal Hypertension: Implications for Disease Progression

open access: yesAlimentary Pharmacology &Therapeutics, Volume 63, Issue 4, Page 538-556, February 2026.
In‐depth multiomics analyses revealed that the gut microbiota in patients with CPH is dysbiotic. Altered gut microbiota plays an important role in the progression of CPH and affects the host's arginine metabolism to promote arginine biosynthesis. The pro‐inflammatory effects of certain gut bacteria induce iNOS expression, which together act on the ...
Qun Zhang   +15 more
wiley   +1 more source

Metabolome Atlas of Brain Reveals Regional Shared and Unique Metabolic Drifts in Response to Type 2 Diabetes in Male Mice

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
A detailed metabolome atlas of the male mouse brain was established, incorporating metabolomic and lipidomic profiling of seven anatomical regions. T2D induced marked metabolic alterations, which were mainly associated with lipotoxicity, defective energy metabolism, proinflammatory processes, and neurotoxicity.
Yang Zhou   +5 more
wiley   +1 more source

Evaluating green techniques for the extraction of L-citrulline from watermelon rind

open access: yesFood Chemistry Advances
L-Citrulline, a non-essential amino acid found abundantly in watermelon, provides potential antioxidant properties and promotes blood vessel dilation in the body.
Mahsa Mohseni   +3 more
doaj   +1 more source

l-(+)Citrulline [PDF]

open access: yesBiochemical Journal, 1939
A G, Gornall, A, Hunter
openaire   +2 more sources

L-Citrulline and L-Arginine Supplementation in Cardiovascular and Exercise Physiology - A Comprehensive Review on Endothelial Function, Blood Pressure, and Physical Performance

open access: yesQuality in Sport
Introduction and Purpose: L-citrulline and L-arginine are amino acids involved in nitric oxide (NO) synthesis, which plays a vital role in regulating vascular tone, arterial pressure, and exercise-induced physiological responses.
Piotr Dembicki   +9 more
doaj   +1 more source

Plasma Citrulline in the Diagnosis and Follow-Up of Celiac Disease

open access: yesChildren
Background/Objectives: Citrulline, an amino acid produced by small bowel enterocytes, has been proposed as a potential marker of intestinal absorptive capacity.
Alicia Isabel Pascual Pérez   +6 more
doaj   +1 more source

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