Results 121 to 130 of about 24,681,778 (305)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
, 2019 Bivariate graph showing size distribution of Tuzoia spp. from the Balang and Kaili biotas (T. sinensis Pan, 1957 in purple; T. lazizhaiensis sp. nov. in blue, and T. bispinosa Yuan & Zhao, 1999 in red); valve length (L) on x-axis, and valve height (H) on
Loren Babcock (8137413) +11 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
A Model of L-H transitionトカマクプラズマにおけるL-H遷移に対する1つのモデルが提案されている。それは散逸性ドリフト波不安定性理論においてある条件を境にして理論的取扱いが異なり、それによって拡散係数のプラズマ・パラメータ依存性が大きく異なることから、L-H遷移が起こり得ることを示した。このモデルから求められる電子温度の閾値を示した。又、このモデルを基に、ASDEXの実験結果に、あてはめたところ大変、良い一致を示した。また、その他の装置のこれまでのさまざまな実験結果とも比較検討を行い、ほとんどの実験結果を説明し得ることを示した。
openaire +1 more source
Dynamic behaviour of the L-H transition in ASDEX-Upgrade
, 1993 The dynamic behaviour of the L-H transition in ASDEX-Upgrade is described. We focus on the periodic L-H-L transitions known as 'dithering H-mode' and show that there is an intrinsic timescale in this process which is characteristic for the L-H transition.
ICRH-Group +4 more
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Transition metal complexes with thiosemicarbazide-based ligands. Part 51. Square-planar nickel(II) complex with acetylacetone bis(S-n-propylisothiosemicarbazone) (L). Crystal and molecular structure of [Ni(L-H)]NCS and two isomorphic complexes [Ni(L-H)]I·EtOH and [Ni(L-H)]I·iPrOH [PDF]
Journal of the Serbian Chemical Society, 2006 The template reaction of a warm methanolic solution of Ni(OAc)2·4H2O, S-n-propylisothiosemicarbazide hydroiodide and acetylacetone yielded the needle- like, brown, diamagnetic complex [Ni(L–H)]I·MeOH, and in the presence of an excess of NH 4NCS, brown ...
VUKADIN M. LEOVAC +3 more
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Leaching of NMC industrial black mass in the presence of LFP
Scientific ReportsThis study focuses on the effect of an emerging source of waste, lithium iron phosphate (LFP) cathode materials, on the hydrometallurgical recycling of the currently dominant industrial battery waste that is rich in transition metals (Ni, Co, Mn, and Li).
Yuanmin Zou +4 more
doaj +1 more source