Results 151 to 160 of about 414,201 (353)

A role for von Hippel-Lindau protein in pancreatic beta-cell function. [PDF]

, 2009
ObjectiveThe Vhlh gene codes for the von Hippel-Lindau protein (VHL), a tumor suppressor that is a key player in the cellular response to oxygen sensing.
Cano, David A, Hebrok, Matthias, Puri, Sapna   +2 more
core  

A thermophilic L-lactic acid producer of high optical purity: isolation and identification

Foods and Raw Materials
Biodegradable polymers, specifically polylactide, are an important part of food packaging and medical devices. Microbiological synthesis uses cheap renewable raw materials and industrial waste to produce a high yield of lactic acid, the monomer of ...
Mariia V. Romanova, Anastasiia N. Dolbunova, Yulia M. Epishkina, Svetlana A. Evdokimova, Mikhail R. Kozlovskiy, Alexander Ye. Kuznetsov, Natalya Yu. Khromova, Andrey V. Beloded   +7 more
doaj   +1 more source

Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA

Advanced Science, EarlyView.
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin, Runyu Cao, Xuemei Bai, Jiahua Yuan, Wanwei Sun, Yi Zheng, Xiaopeng Qi, Wei Zhao, Bingyu Liu, Chengjiang Gao   +9 more
wiley   +1 more source

Oxidation of D-lactate and L-lactate by Neisseria meningitidis: purification and cloning of meningococcal D-lactate dehydrogenase [PDF]

, 1993
Alice L. Erwin, E C Gotschlich
openalex   +1 more source

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

Advanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji, Yongli Ye, Jiadi Sun, Lina Sheng, Jinyou Li, Jin Yang, Bing Wu, Yuting Wang, Xingxing Gao, Liang Luo, Jianfeng Ping, Yinzhi Zhang, Xiulan Sun   +12 more
wiley   +1 more source

Diagnostic Accuracy of Lactate Dehydrogenase and Serum Creatine Kinase to Detect Prenatal Hypoxia in Term Neonates

Pakistan Journal of Medicine and Dentistry
Background: Prenatal hypoxia is a condition where the fetus experiences insufficient oxygen levels and it can lead to morbidity and mortality. This study aimed to evaluate the diagnostic efficacy of the serum CK-MB fraction and LDH for the diagnosis of ...
Sabahat Fatima, Khadija Kiran , Anas Khalil, Jazib Andleeb, Farah Naz Tahir, Zahid Mahmood   +5 more
doaj   +1 more source

L-Lactate Dehydrogenase A Chain

Definitions, 2020

semanticscholar   +1 more source

Phosphorylation‐Dependent Stabilization of Collaborator of ARF (CARF) Suppresses Lymphoma Cell Proliferation

Advanced Science, EarlyView.
This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu, Zhuang Wei, Shuting Zhou, Xiaofan Zhang, Wenjun Zhang, Aibin Liang, Zhe Wang, Hongwei Xue   +7 more
wiley   +1 more source

Integrating bioinformatics and multiple machine learning to identify mitophagy-related targets for the diagnosis and treatment of diabetic foot ulcers: evidence from transcriptome analysis and drug docking

Frontiers in Molecular Biosciences
BackgroundDiabetic foot ulcers are the most common and serious complication of diabetes mellitus, the high morbidity, mortality, and disability of which greatly diminish the quality of life of patients and impose a heavy socioeconomic burden. Thus, it is
Hui Guo, Kui Xiao, Yanhua Zheng, Jianchun Zong   +3 more
doaj   +1 more source

Some Lactobacillus l -Lactate Dehydrogenases Exhibit Comparable Catalytic Activities for Pyruvate and Oxaloacetate [PDF]

, 2001
Kazuhito Arai, Takeo Kamata, H. Uchikoba, Shinya Fushinobu, Hiroshi Matsuzawa, Hayao Taguchi   +5 more
openalex   +1 more source