Results 231 to 240 of about 414,201 (353)

Effects ofN^G-nitro-l-arginine methyl ester on endotoxin-induced leakage of lactate dehydrogenase and cytotoxicity in J774A.1 cells [PDF]

, 2001
Shuhei Sakaguchi, Shinobu Furusawa, Motoaki Takayanagi, Yoshio Takayanagi   +3 more
openalex   +1 more source

Nanoplastics Enhance Transmembrane Transport and Uptake of Carcinogens: Transcriptional Changes and the Effects of Weathering

Advanced Science, EarlyView.
Nanoplastics exposed to defined weathering conditions are systematically investigated as vectors for polycyclic aromatic hydrocarbons (PAHs). This investigation demonstrates significant potential for enhancing PAH uptake and transport in an intestinal membrane model.
Erik B. Schiferle, Saatwik Suman, Katherine R. Steffen, Koustav Kundu, Aniqa N. Islam, Björn M. Reinhard   +5 more
wiley   +1 more source

Decoy Extracellular Vesicles Overcome Triple‐Negative Breast Cancer Heterogeneity via Membrane‐Cytoplasm‐Mitochondria Cascade Targeting

Advanced Science, EarlyView.
siT/MOF@EVs overcome TNBC heterogeneity through a tumor cell membrane–cytoplasm–mitochondria cascade effect, triggering a self‐reinforcing anti‐tumor immune cycle and durable immune memory. The system enables sequential targeting of membrane checkpoints ligands (decoy effect), cytoplasmic siRNA delivery (CSC suppression), and mitochondrial MOF ...
Chuanrong Chen, Ming Shen, Xiaofeng Wan, Lili Sheng, Na Hao, Man Li, Menglin Xu, Yang He, Jiali Zhang   +8 more
wiley   +1 more source

The Effect of Cysteine on L-α-Glycerophosphate and Lactate Dehydrogenase Reactions

, 1968
Achilles Dugaiczyk, Maciej T. Małecki, John J. Eiler   +2 more
openalex   +1 more source

SenExo‐cCCT2 Reprograms Senescence Response and Anti‐Tumor Immunity Following FOLFIRINOX Chemotherapy in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
This study demonstrates that SenExo‐cCCT2 enables targeted delivery of cCCT2 to pancreatic cancer cells, where it disrupts IPO13‐mediated nuclear translocation of UBC9, impairing SUMOylation‐dependent DNA damage repair and inducing senescence. Senescent tumor cells secrete CXCL10 to recruit CD8⁺ T‐cells while upregulating PD‐L1.
Shuncang Zhu, Yinhao Chen, Hongyi Lin, Jinpeng Lu, Yu Pan, Ge Li, Yongding Wu, Haoxiang Zhang, Xiaoxiao Huang, Yiting Chen, Huangjing Chen, Long Jin, Min Huang, Chengyu Liao, Long Huang, Yifeng Tian, Zuwei Wang, Qiaowei Li, Shi Chen   +18 more
wiley   +1 more source

The ldhA Gene, Encoding Fermentative l-Lactate Dehydrogenase of Corynebacterium glutamicum, Is under the Control of Positive Feedback Regulation Mediated by LldR

Journal of Bacteriology, 2009
Koichi Toyoda, H. Teramoto, M. Inui, H. Yukawa   +3 more
semanticscholar   +1 more source

Investigations of Yeast L-Lactate Dehydrogenase (Cytochrome b2)

, 1968
Julian M. Sturtevant, Tian Yow Tsong
openalex   +1 more source

Detection ofL-lactate in polyethylene glycol solutions confirms the identity of the active-site ligand in a proline dehydrogenase structure [PDF]

, 2004
Min Zhang, John J. Tanner
openalex   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

Investigations of Yeast l-Lactate Dehydrogenase (Cytochrome b2)

, 1965
Keitarō Hiromi, Julian M. Sturtevant
openalex   +1 more source