Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz +431 more
core +2 more sources
Objective: To determine the diagnostic accuracy of the Lactate Dehydrogenase, C-Reactive Protein and Ferritin in suspected patients of COVID-19. Study Design: Cross-sectional validation study.
Tayyaba Ashiq +5 more
doaj
Diets for feedlot cattle must be a higher energy density, entailing high fermentable carbohydrate content. Feed additives are needed to reduce possible metabolic disorders. This study aimed to analyze the post-rumen effects of different levels of starch (
Leone Campos Rocha +10 more
doaj +1 more source
Expression of Microbial Enzymes in Mammalian Astrocytes to Modulate Lactate Release
Astrocytes support and modulate neuronal activity through the release of L-lactate. The suggested roles of astrocytic lactate in the brain encompass an expanding range of vital functions, including central control of respiration and cardiovascular ...
Barbara Vaccari Cardoso +5 more
doaj +1 more source
Investigations of Yeast L-Lactate Dehydrogenase (Cytochrome b2)
Tian Yow Tsong, Julian M. Sturtevant
openalex +2 more sources
Using blubber explants to investigate adipose function in grey seals:glycolytic, lipolytic and gene expression responses to glucose and hydrocortisone [PDF]
Adipose tissue is fundamental to energy balance, which underpins fitness and survival. Knowledge of adipose regulation in animals that undergo rapid fat deposition and mobilisation aids understanding of their energetic responses to rapid environmental ...
Bennett, Kimberley A. +4 more
core +3 more sources
Serine biosynthesis with one carbon catabolism represents a novel pathway for ATP generation in cells using alternative glycolysis with zero net ATP production [PDF]
Recent experimental evidence indicates that some cancer cells have an alternative glycolysis pathway with net zero ATP production, implying that upregulation of glycolysis in these cells may not be related to the generation of ATP.
Alexei Vazquez +2 more
core +2 more sources
Formate Excretion in Urine of Rats Fed Dimethylaminoazobenzene-rich Diets: The Possibility of Formate Formation from D-Lactate [PDF]
This experiment was carried out to evaluate the possibility of degradation of d-lactate into formate and acetaldehyde. In order to induce hyperproduction of d-lactate in rats.
Kawase, Michi +2 more
core +1 more source
Construction Of Recombinant Escherichia Coli Bad85 For The Production Of High Purity L-Lactic Acid [PDF]
Lactate dehydrogenase (LDH, EC 1.1.1.27) catalyzes the oxidation of pyruvate to lactate in facultative anaerobes. Two forms of lactate dehydrogenase with different substrate specificities have been identified namely the L-lactate dehydrogenase (EC 1.1.1 ...
Tengku Zainal Mulok, Tengku Elida
core
High cycling cadence reduces carbohydrate oxidation at given low intensity metabolic rate [PDF]
Cycling cadence (RPM)-related differences in blood lactate concentration (BLC) increase with increasing exercise intensity, whilst corresponding divergences in oxygen uptake (VO2) and carbon dioxde production (VCO2) decrease.
Alkhatib, Ahmad, Beneke, Ralph
core +6 more sources

