Results 41 to 50 of about 275,928 (338)

Hyperpolarized 13C Magnetic Resonance Spectroscopic Imaging of Pyruvate Metabolism in Murine Breast Cancer Models of Different Metastatic Potential

open access: yesMetabolites, 2021
This study uses dynamic hyperpolarized [1-13C]pyruvate magnetic resonance spectroscopic imaging (MRSI) to estimate differences in glycolytic metabolism between highly metastatic (4T1, n = 7) and metastatically dormant (4T07, n = 7) murine breast cancer ...
Erin B. Macdonald   +9 more
doaj   +1 more source

Functional responses of methanogenic archaea to syntrophic growth. [PDF]

open access: yes, 2012
Methanococcus maripaludis grown syntrophically with Desulfovibrio vulgaris was compared with M. maripaludis monocultures grown under hydrogen limitation using transcriptional, proteomic and metabolite analyses.
Arkin, Adam P   +13 more
core   +2 more sources

Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]

open access: yes, 2018
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz   +431 more
core   +2 more sources

DETERMINATION OF DIAGNOSTIC ACCURACY OF BIOCHEMICAL PARAMETERS (CRP, LDH & FERRITIN) IN THE DIAGNOSIS OF COVID-19 IN SUSPECTED COVID CASES

open access: yesPakistan Armed Forces Medical Journal, 2021
Objective: To determine the diagnostic accuracy of the Lactate Dehydrogenase, C-Reactive Protein and Ferritin in suspected patients of COVID-19. Study Design: Cross-sectional validation study.
Tayyaba Ashiq   +5 more
doaj  

Feedlot diets containing different starch levels and additives change the cecal proteome involved in cattle’s energy metabolism and inflammatory response

open access: yesScientific Reports, 2022
Diets for feedlot cattle must be a higher energy density, entailing high fermentable carbohydrate content. Feed additives are needed to reduce possible metabolic disorders. This study aimed to analyze the post-rumen effects of different levels of starch (
Leone Campos Rocha   +10 more
doaj   +1 more source

Expression of Microbial Enzymes in Mammalian Astrocytes to Modulate Lactate Release

open access: yesBrain Sciences, 2021
Astrocytes support and modulate neuronal activity through the release of L-lactate. The suggested roles of astrocytic lactate in the brain encompass an expanding range of vital functions, including central control of respiration and cardiovascular ...
Barbara Vaccari Cardoso   +5 more
doaj   +1 more source

High cycling cadence reduces carbohydrate oxidation at given low intensity metabolic rate [PDF]

open access: yes, 2014
Cycling cadence (RPM)-related differences in blood lactate concentration (BLC) increase with increasing exercise intensity, whilst corresponding divergences in oxygen uptake (VO2) and carbon dioxde production (VCO2) decrease.
Alkhatib, Ahmad, Beneke, Ralph
core   +6 more sources

Electron transport phosphorylation in rumen butyrivibrios: unprecedented ATP yield for glucose fermentation to butyrate. [PDF]

open access: yes, 2015
From a genomic analysis of rumen butyrivibrios (Butyrivibrio and Pseudobutyrivibrio sp.), we have re-evaluated the contribution of electron transport phosphorylation (ETP) to ATP formation in this group.
Firkins, Jeffrey L, Hackmann, Timothy J
core   +2 more sources

Amperometric L-Lactate Biosensor Based upon a Gold Nanoparticles/Reduced Graphene Oxide/Polyallylamine Hydrochloride Modified Screen-Printed Graphite Electrode

open access: yesChemosensors, 2021
This work describes a novel L-lactate biosensor based on the immobilization of L-lactate dehydrogenase enzyme on the screen-printed electrode modified with a ternary composite based on gold nanoparticles, electrochemically-reduced graphene oxide, and ...
Oana-Maria Istrate   +2 more
doaj   +1 more source

Construction Of Recombinant Escherichia Coli Bad85 For The Production Of High Purity L-Lactic Acid [PDF]

open access: yes, 2008
Lactate dehydrogenase (LDH, EC 1.1.1.27) catalyzes the oxidation of pyruvate to lactate in facultative anaerobes. Two forms of lactate dehydrogenase with different substrate specificities have been identified namely the L-lactate dehydrogenase (EC 1.1.1 ...
Tengku Zainal Mulok, Tengku Elida
core  

Home - About - Disclaimer - Privacy