Results 41 to 50 of about 229,589 (299)

Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology [PDF]

, 2011
Aerobic glycolysis is a seemingly wasteful mode of ATP production that is seen both in rapidly proliferating mammalian cells and highly active contracting muscles, but whether there is a common origin for its presence in these widely different systems is
Vazquez, Alexei, Oltvai Zoltán N., Vazquez, A, Zoltán N Oltvai, Alexei Vazquez, Vazquez Alexei, Oltvai, ZN, Oltvai, Zoltán N., Zoltán N. Oltvai   +8 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Serum and Cerebrospinal Fluid Lactate Dehydrogenase in Children with Febrile Convulsions [PDF]

, 2023
  Objective Tissue damage caused by febrile convulsion has not still been proved or refuted completely. Given the fact that lactate dehydrogenase as an intracellular enzyme can be increased due to tissue damage, we decided to evaluate serum and ...
Ahmadi Aliabadi, Leila, bidabadi, Elham, Mashouf, Parham, Tohidi, Sepehr, Hasandokht, Tolou, Shahraki, Tamkin, Khosousi, Mohammad-Javad   +6 more
core   +2 more sources

The Activity of Antioxidant and Anaerobic Glycolysis Enzymes Under Thermal Gradient Exposure in Palearctic Species Lymnaea stagnalis [PDF]

Journal of Stress Physiology & Biochemistry, 2013
The aim of present study was the evaluation of antioxidant (peroxidase, catalase, glutathione S transferase) and anaerobic glycolysis (lactate dehydrogenase) enzymes activity under thermal gradient in Palearctic species Lymnaea stagnalis ...
Vereshchagina К.P., Lubyaga J.А., Gurkov А.N., Shchapova Е.P., Madyarova E.V., Kondrat’eva Е.М., Golubev А.P., Timofeyev М.А., Aksenov-Gribanov D.V.   +8 more
doaj  

Regulatory Mechanisms of L-Lactic Acid and Taste Substances in Chinese Acid Rice Soup (Rice-Acid) Fermented With a Lacticaseibacillus paracasei and Kluyveromyces marxianus

Frontiers in Microbiology, 2021
Rice-acid has abundant taste substances and health protection function due to the various bioactive compounds it contains, including organic acids. L-lactic acid is the most abundant organic acid in rice-acid, but the regulatory mechanisms of L-lactic ...
Na Liu, Na Liu, Likang Qin, Likang Qin, Song Miao   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Feedlot diets containing different starch levels and additives change the cecal proteome involved in cattle’s energy metabolism and inflammatory response

Scientific Reports, 2022
Diets for feedlot cattle must be a higher energy density, entailing high fermentable carbohydrate content. Feed additives are needed to reduce possible metabolic disorders. This study aimed to analyze the post-rumen effects of different levels of starch (
Leone Campos Rocha, Andrey Sávio de Almeida Assunção, Renata Aparecida Martins, Victor Valério de Carvalho, Alexandre Perdigão, Marília Afonso Rabelo Buzalaf, Jiri Adamec, Camila Pereira Braga, Danilo Domingues Millen, José Cavalcante Souza Vieira, Pedro de Magalhães Padilha   +10 more
doaj   +1 more source

Hyperpolarized ¹³C Magnetic Resonance Spectroscopic Imaging of Pyruvate Metabolism in Murine Breast Cancer Models of Different Metastatic Potential

Metabolites, 2021
This study uses dynamic hyperpolarized [1-13C]pyruvate magnetic resonance spectroscopic imaging (MRSI) to estimate differences in glycolytic metabolism between highly metastatic (4T1, n = 7) and metastatically dormant (4T07, n = 7) murine breast cancer ...
Erin B. Macdonald, Paul Begovatz, Gregory P. Barton, Sarah Erickson-Bhatt, David R. Inman, Benjamin L. Cox, Kevin W. Eliceiri, Roberta M. Strigel, Suzanne M. Ponik, Sean B. Fain   +9 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Highly efficient L-lactate production using engineered Escherichia coli with dissimilar temperature optima for L-lactate formation and cell growth [PDF]

, 2014
CITATION: Niu, D. et al. 2014. Highly efficient L-lactate production using engineered Escherichia coli with dissimilar temperature optima for L-lactate formation and cell growth.
Suren Singh, Singh, Suren, Kangming Tian, Fuping Lu, Niu, Dandan, Prior, Bernard A., Bernard A Prior, Tian, Kangming, Min Wang, Lu, Fuping, Wang, Min, Wang, Zhengxiang, Dandan Niu, Zhengxiang Wang   +13 more
core   +1 more source