Results 31 to 40 of about 13,561,049 (255)

Null and electrophoretic mobility mutants in the structural gene for L-lactate dehydrogenase of Saccharomyces cerevisiae [PDF]

, 1986
A mutant lacking L-lactate dehydrogenase (EC 1.1.2.3) of Saccharomyces cerevisiae was isolated by its inability to grow on minimal medium with L-lactate as a carbon source.
Sbragia, Ralph, Christopher Wills, Wills, Christopher, Ralph Sbragia, Rush, Karen, Karen Rush   +5 more
core   +1 more source

Identification of the genes that contribute to lactate utilization in Helicobacter pylori. [PDF]

PLoS ONE, 2014
Helicobacter pylori are Gram-negative, spiral-shaped microaerophilic bacteria etiologically related to gastric cancer. Lactate utilization has been implicated although no corresponding genes have been identified in the H. pylori genome.
Shun Iwatani, Hiroyuki Nagashima, Rita Reddy, Seiji Shiota, David Y Graham, Yoshio Yamaoka   +5 more
doaj   +1 more source

Significance of Elevated Synovial Fluid Lactic Acid and Lactate Dehydrogenase Levels in Differentiating Between Septic Arthritis, Inflammatory Arthritis and Non-Inflammatory Arthritis

Pakistan Armed Forces Medical Journal, 2022
Objective: To determine the lactic acid and lactate dehydrogenase levels in synovial fluid and differentiate between inflammatory and non-inflammatory arthritis. Study Design: Cross-sectional study.
Uzma Erum, Tahira Perveen Umer, Shafiq-ur Rehman Arain, Muhammad Rashid Ahmed, Lubna Nazir   +4 more
doaj   +1 more source

Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology [PDF]

, 2011
Aerobic glycolysis is a seemingly wasteful mode of ATP production that is seen both in rapidly proliferating mammalian cells and highly active contracting muscles, but whether there is a common origin for its presence in these widely different systems is
Vazquez, Alexei, Oltvai Zoltán N., Vazquez, A, Zoltán N Oltvai, Alexei Vazquez, Vazquez Alexei, Oltvai, ZN, Oltvai, Zoltán N., Zoltán N. Oltvai   +8 more
core   +2 more sources

Serum and Cerebrospinal Fluid Lactate Dehydrogenase in Children with Febrile Convulsions [PDF]

, 2023
  Objective Tissue damage caused by febrile convulsion has not still been proved or refuted completely. Given the fact that lactate dehydrogenase as an intracellular enzyme can be increased due to tissue damage, we decided to evaluate serum and ...
Ahmadi Aliabadi, Leila, bidabadi, Elham, Mashouf, Parham, Tohidi, Sepehr, Hasandokht, Tolou, Shahraki, Tamkin, Khosousi, Mohammad-Javad   +6 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The Activity of Antioxidant and Anaerobic Glycolysis Enzymes Under Thermal Gradient Exposure in Palearctic Species Lymnaea stagnalis [PDF]

Journal of Stress Physiology & Biochemistry, 2013
The aim of present study was the evaluation of antioxidant (peroxidase, catalase, glutathione S transferase) and anaerobic glycolysis (lactate dehydrogenase) enzymes activity under thermal gradient in Palearctic species Lymnaea stagnalis ...
Vereshchagina К.P., Lubyaga J.А., Gurkov А.N., Shchapova Е.P., Madyarova E.V., Kondrat’eva Е.М., Golubev А.P., Timofeyev М.А., Aksenov-Gribanov D.V.   +8 more
doaj  

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Feedlot diets containing different starch levels and additives change the cecal proteome involved in cattle’s energy metabolism and inflammatory response

Scientific Reports, 2022
Diets for feedlot cattle must be a higher energy density, entailing high fermentable carbohydrate content. Feed additives are needed to reduce possible metabolic disorders. This study aimed to analyze the post-rumen effects of different levels of starch (
Leone Campos Rocha, Andrey Sávio de Almeida Assunção, Renata Aparecida Martins, Victor Valério de Carvalho, Alexandre Perdigão, Marília Afonso Rabelo Buzalaf, Jiri Adamec, Camila Pereira Braga, Danilo Domingues Millen, José Cavalcante Souza Vieira, Pedro de Magalhães Padilha   +10 more
doaj   +1 more source