Results 11 to 20 of about 13,561,049 (255)

NAD-independent L-lactate dehydrogenase is required for L-lactate utilization in Pseudomonas stutzeri SDM. [PDF]

PLoS ONE, 2012
BACKGROUND: Various Pseudomonas strains can use L-lactate as their sole carbon source for growth. However, the L-lactate-utilizing enzymes in Pseudomonas have never been identified and further studied. METHODOLOGY/PRINCIPAL FINDINGS: An NAD-independent L-
Chao Gao, Tianyi Jiang, Peipei Dou, Cuiqing Ma, Lixiang Li, Jian Kong, Ping Xu   +6 more
doaj   +2 more sources

Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate [PDF]

BMC Microbiology, 2010
Background Corynebacterium glutamicum is able to grow with lactate as sole or combined carbon and energy source. Quinone-dependent L-lactate dehydrogenase LldD is known to be essential for utilization of L-lactate by C. glutamicum.
Oikawa Tadao, Matsui Daisuke, Stansen K Corinna, Youn Jung-Won, Kato Osamu, Wendisch Volker F   +5 more
doaj   +2 more sources

Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase [PDF]

, 2023
Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover.
Hicks, Kevin G., Fogarty, Sarah, Sun, Pengkai, Ahn, Hee Chul, Gasper, William C., Cluntun, Ahmad A., Allen, Karen N., Webb, Bradley A., Wang, Bei, Nonato, Maria Cristina, Cardoso, Iara A., Ho, Quinn, Rutter, Jared, Guzman, Andrea, Block, Samuel, Palladino, Michael J, Ajalla Aleixo, Mariana A., Prajapati, Sabin, Leifer, Aaron, Berg, Jordan A., Tittmann, Kai, Leonard, Paul G., Chang, Fei, Zhou, Youjia, Bott, Alex J., Salvatore, Sonia R., Schopfer, Francisco J., Hackett, Sean R., Unterlass, Judith, Tilley, Samantha, Arok, Ajak, Matsuura, Atsushi, Ding, Jianping, Tolan, Dean R., Cox, James E., Blevins, Aubrie, Schubert, Heidi L., Yun, Cai Hong, Muller, Florian L., Zhao, Pengkai, Dreveny, Ingrid, Vander Heiden, Matthew G., Barta, Paige, VanDemark, Andrew P., Hill, Christopher P., Winter, Jacob M.   +45 more
core   +1 more source

Bioinformatics Analysis and Gene Cloning of L-Lactate Dehydrogenase from Lactobacillus rhamnosus

Shipin gongye ke-ji, 2023
In this study, L-lactate dehydrogenase (Lr-L-LDH) from Lactobacillus rhamnosus was investigated. The well-known Lr-L-LDH1 was taken as the control, differences between Lr-L-LDH1 and Lr-L-LDH2 annotated from the genome of L. rhamnosus were analyzed.
Liming XU, Guofeng JIANG, Xinling WU, Xiufang LIAO, Xiajie LAO, Hanchun YA, Xiunian LI   +6 more
doaj   +1 more source

An Oxygen-Insensitive Biosensor and a Biofuel Cell Device based on FMN L-lactate Dehydrogenase [PDF]

, 2022
Lactate sensing has high importance for metabolic diseases diagnostics, food spoilage, sports medicine, or the construction of biofuel cell devices. Therefore, continuous lactate sensing devices which enable accurate detection should be developed.
Yifat, Cohen, Omer, Yehezkeli, Nidaa , Herzallh, Roy , Cohen, Matan , Meirovich, Liora , Frech, Oren , Bachar   +6 more
core   +2 more sources

CSF lactate dehydrogenase activity in patients with Creutzfeldt-Jakob disease exceeds that in other dementias [PDF]

, 2004
The diagnosis of Creutzfeldt- Jakob disease (CJD) is still made by exclusion of other dementias. We now evaluated lactate dehydrogenase (LDH) in the cerebrospinal fluid (CSF) as a possible additional diagnostic tool. CSF LDH levels of patients with CJD (
Cepek, L., Niedmann, P., Poser, S., Otto, M., Kretzschmar, Hans A., Otto, Markus, Poser, Sigrid, Schmidt, H., Schroter, A., Kretzschmar, H. A.   +9 more
core   +1 more source

Lactate dehydrogenase and glycerol-3-phosphate dehydrogenase cooperatively regulate growth and carbohydrate metabolism during Drosophila melanogaster larval development [PDF]

, 2019
The dramatic growth that occurs during Drosophila larval development requires rapid conversion of nutrients into biomass. Many larval tissues respond to these biosynthetic demands by increasing carbohydrate metabolism and lactate dehydrogenase (LDH ...
Tennessen, Jason M., Pletcher, Rose C., Gosney, Chelsea J., Buddika, Kasun, Chawla, Geetanjali, Sterrett, Maria, Tennessen, Jason, Sokol, Nicholas Samuel, Burton, Anna K., Li, Hongde, Karty, Jonathan A., Julick, Cole R., Montooth, Kristi L., Sterrett, Maria C., Rai, Madhulika, Mahmoudzadeh, Nader H., Karty, Jonathan Allen, Sokol, Nicholas A., Luhur, Arthur   +18 more
core   +1 more source

L-lactate exerts a pro-proliferative effect on adult hippocampal precursor cells in vitro

iScience, 2021
Summary: L-lactate has energetic and signaling properties, and its availability is modulated by activity-dependent stimuli, which also regulate adult hippocampal neurogenesis.
Alexandra Pötzsch, Sara Zocher, Stefanie N. Bernas, Odette Leiter, Annette E. Rünker, Gerd Kempermann   +5 more
doaj   +1 more source

Glycerol dehydrogenase: Structure, specificity, and mechanism of a family III polyol dehydrogenase [PDF]

, 2001
Background: Bacillus stearothermophilus glycerol dehydrogenase (GlyDH) (glycerol:NAD+ 2-oxidoreductase, EC 1.1.1.6) catalyzes the oxidation of glycerol to dihydroxyacetone (1,3-dihydroxypropanone) with concomitant reduction of NAD+ to NADH.
Baker PJ, Sveta Sedelnikova, Taylor R, Sedelnikova S, Baker, Patrick J., Rice DW, Muir, Nicola M., Gore, Michael G., Burke J, David W. Rice, Ruzheinikov, Sergey N., Bullough, Per A., Sedelnikova, Sveta, Sergey N. Ruzheinikov, Per A. Bullough, Patrick J. Baker, Gore MG, Burke, Jacky, Michael G. Gore, Muir NM, Bullough PA, Nicola M. Muir, Rice, David W., Robert Taylor, Ruzheinikov SN, Jacky Burke, Taylor, Robert   +26 more
core   +1 more source

Elevated LDH greater than 400 U/L portends poorer overall survival in diffuse large B-cell lymphoma patients treated with CD19 CAR-T cell therapy in a real world multi-ethnic cohort

Experimental Hematology & Oncology, 2021
Anti-CD19 chimeric antigen receptor T-cell therapies have shown striking clinical activity in diffuse large B-cell lymphoma but robust biomarkers predictive of responsiveness are still needed.
Emma Rabinovich, Kith Pradhan, R. Alejandro Sica, Lizamarie Bachier-Rodriguez, Ioannis Mantzaris, Noah Kornblum, Aditi Shastri, Kira Gritsman, Mendel Goldfinger, Amit Verma, Ira Braunschweig   +10 more
doaj   +1 more source