Results 21 to 30 of about 183,054 (259)

Colonocyte-derived lactate promotes E. coli fitness in the context of inflammation-associated gut microbiota dysbiosis

Microbiome, 2022
Background Intestinal inflammation disrupts the microbiota composition leading to an expansion of Enterobacteriaceae family members (dysbiosis). Associated with this shift in microbiota composition is a profound change in the metabolic landscape of the ...
Savannah J. Taylor, Maria G. Winter, Caroline C. Gillis, Laice Alves da Silva, Amanda L. Dobbins, Matthew K. Muramatsu, Angel G. Jimenez, Rachael B. Chanin, Luisella Spiga, Ernesto M. Llano, Vivian K. Rojas, Jiwoong Kim, Renato L. Santos, Wenhan Zhu, Sebastian E. Winter   +14 more
doaj   +1 more source

Relative catalytic efficiencies and transcript levels of three d‐ and two l‐lactate dehydrogenases for optically pure d‐lactate production in Sporolactobacillus inulinus

MicrobiologyOpen, 2019
As the optical purity of the lactate monomer is pivotal for polymerization, the production of optically pure d‐lactate is of significant importance. Sporolactobacillus inulinus YBS1‐5 is a superior optically pure d‐lactate‐producing bacterium.
Bin Wu, Qi Yu, Shan Zheng, Marcelo Monteiro Pedroso, Luke W. Guddat, Bingfang He, Gerhard Schenk   +6 more
doaj   +1 more source

Non-sterilized fermentation of high optically pure d-lactic acid by a genetically modified thermophilic Bacillus coagulans strain

Microbial Cell Factories, 2017
Background Optically pure d-lactic acid (≥ 99%) is an important precursor of polylactic acid. However, there are relatively few studies on d-lactic acid fermentation compared with the extensive investigation of l-lactic acid production.
Caili Zhang, Cheng Zhou, Nilnate Assavasirijinda, Bo Yu, Limin Wang, Yanhe Ma   +5 more
doaj   +1 more source

Identification of the genes that contribute to lactate utilization in Helicobacter pylori. [PDF]

PLoS ONE, 2014
Helicobacter pylori are Gram-negative, spiral-shaped microaerophilic bacteria etiologically related to gastric cancer. Lactate utilization has been implicated although no corresponding genes have been identified in the H. pylori genome.
Shun Iwatani, Hiroyuki Nagashima, Rita Reddy, Seiji Shiota, David Y Graham, Yoshio Yamaoka   +5 more
doaj   +1 more source

Regulatory Mechanisms of L-Lactic Acid and Taste Substances in Chinese Acid Rice Soup (Rice-Acid) Fermented With a Lacticaseibacillus paracasei and Kluyveromyces marxianus

Frontiers in Microbiology, 2021
Rice-acid has abundant taste substances and health protection function due to the various bioactive compounds it contains, including organic acids. L-lactic acid is the most abundant organic acid in rice-acid, but the regulatory mechanisms of L-lactic ...
Na Liu, Na Liu, Likang Qin, Likang Qin, Song Miao   +4 more
doaj   +1 more source

The Core of Allosteric Motion in Thermus caldophilus l-Lactate Dehydrogenase [PDF]

Journal of Biological Chemistry, 2014
For Thermus caldophilus L-lactate dehydrogenase (TcLDH), fructose 1,6-bisphosphate (FBP) reduced the pyruvate S(0.5) value 10(3)-fold and increased the V(max) value 4-fold at 30 °C and pH 7.0, indicating that TcLDH has a much more T state-sided allosteric equilibrium than Thermus thermophilus L-lactate dehydrogenase, which has only two amino acid ...
Yoko Ikehara, Kazuhito Arai, Nayuta Furukawa, Tadashi Ohno, Tatsuya Miyake, Shinya Fushinobu, Masahiro Nakajima, Akimasa Miyanaga, Hayao Taguchi   +8 more
openaire   +2 more sources

DETERMINATION OF DIAGNOSTIC ACCURACY OF BIOCHEMICAL PARAMETERS (CRP, LDH & FERRITIN) IN THE DIAGNOSIS OF COVID-19 IN SUSPECTED COVID CASES

Pakistan Armed Forces Medical Journal, 2021
Objective: To determine the diagnostic accuracy of the Lactate Dehydrogenase, C-Reactive Protein and Ferritin in suspected patients of COVID-19. Study Design: Cross-sectional validation study.
Tayyaba Ashiq, Abdus Sattar, Nasir Uddin, Qamar Bashir, Sajida Shaheen, Aamir Ijaz   +5 more
doaj  

Hyperpolarized ¹³C Magnetic Resonance Spectroscopic Imaging of Pyruvate Metabolism in Murine Breast Cancer Models of Different Metastatic Potential

Metabolites, 2021
This study uses dynamic hyperpolarized [1-13C]pyruvate magnetic resonance spectroscopic imaging (MRSI) to estimate differences in glycolytic metabolism between highly metastatic (4T1, n = 7) and metastatically dormant (4T07, n = 7) murine breast cancer ...
Erin B. Macdonald, Paul Begovatz, Gregory P. Barton, Sarah Erickson-Bhatt, David R. Inman, Benjamin L. Cox, Kevin W. Eliceiri, Roberta M. Strigel, Suzanne M. Ponik, Sean B. Fain   +9 more
doaj   +1 more source

Feedlot diets containing different starch levels and additives change the cecal proteome involved in cattle’s energy metabolism and inflammatory response

Scientific Reports, 2022
Diets for feedlot cattle must be a higher energy density, entailing high fermentable carbohydrate content. Feed additives are needed to reduce possible metabolic disorders. This study aimed to analyze the post-rumen effects of different levels of starch (
Leone Campos Rocha, Andrey Sávio de Almeida Assunção, Renata Aparecida Martins, Victor Valério de Carvalho, Alexandre Perdigão, Marília Afonso Rabelo Buzalaf, Jiri Adamec, Camila Pereira Braga, Danilo Domingues Millen, José Cavalcante Souza Vieira, Pedro de Magalhães Padilha   +10 more
doaj   +1 more source

Evidence that L-(+)-lactate dehydrogenase deficiency is lethal in Streptococcus mutans [PDF]

Infection and Immunity, 1994
In order to construct an effector strain for the replacement therapy of dental caries, we wished to combine the properties of low-level acid production and high-level colonization potential in a strain of Streptococcus mutans. To this end, we made a deletion in the lactate dehydrogenase (LDH) gene cloned from the bacteriocin-producing S.
J D, Hillman, A, Chen, M, Duncan, S W, Lee   +3 more
openaire   +2 more sources