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Bioinformatics Analysis and Gene Cloning of L-Lactate Dehydrogenase from Lactobacillus rhamnosus
Shipin gongye ke-ji, 2023 In this study, L-lactate dehydrogenase (Lr-L-LDH) from Lactobacillus rhamnosus was investigated. The well-known Lr-L-LDH1 was taken as the control, differences between Lr-L-LDH1 and Lr-L-LDH2 annotated from the genome of L. rhamnosus were analyzed.
Liming XU +6 more
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D- and L-lactate dehydrogenases during invertebrate evolution [PDF]
BMC Evolutionary Biology, 2008 The L-lactate and D-lactate dehydrogenases, which are involved in the reduction of pyruvate to L(-)-lactate and D(+)-lactate, belong to evolutionarily unrelated enzyme families. The genes encoding L-LDH have been used as a model for gene duplication due to the multiple paralogs found in eubacteria, archaebacteria, and eukaryotes.
Cristescu, M.E. +3 more
openaire +3 more sources
Quantitative constraint-based computational model of tumor-to-stroma coupling via lactate shuttle [PDF]
, 2015 Cancer cells utilize large amounts of ATP to sustain growth, relying primarily on non-oxidative, fermentative pathways for its production. In many types of cancers this leads, even in the presence of oxygen, to the secretion of carbon equivalents ...
Capuani, Fabrizio +3 more
core +3 more sources
L-lactate exerts a pro-proliferative effect on adult hippocampal precursor cells in vitro
iScience, 2021 Summary: L-lactate has energetic and signaling properties, and its availability is modulated by activity-dependent stimuli, which also regulate adult hippocampal neurogenesis.
Alexandra Pötzsch +5 more
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l-Lactate generates hydrogen peroxide in purified rat liver mitochondria due to the putative l-lactate oxidase localized in the intermembrane space [PDF]
, 1922 In order to ascertain whether and how mitochondria can produce hydrogen peroxide (H2O2) as a result of l-lactate addition, we monitored H2O2 generation in rat liver mitochondria and in submitochondrial fractions free of peroxisomal and cytosolic ...
de Bari, Lidia +3 more
core +2 more sources
Efficient synthesis of L-lactic acid from glycerol by metabolically engineered Escherichia coli [PDF]
, 2013 Due to its abundance and low-price, glycerol has become an attractive carbon source for the industrial production of value-added fuels and chemicals. This work reports the engineering of E.
Blankschien, Matthew D +3 more
core +2 more sources
Experimental Hematology & Oncology, 2021 Anti-CD19 chimeric antigen receptor T-cell therapies have shown striking clinical activity in diffuse large B-cell lymphoma but robust biomarkers predictive of responsiveness are still needed.
Emma Rabinovich +10 more
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Redox Biology, 2020 Research over the past seventy years has established that mitochondrial-l-lactate dehydrogenase (m-L-LDH) is vital for mitochondrial bioenergetics. However, in recent report, Fulghum et al.
Adrian Young +2 more
doaj +1 more source
Serum lactate dehydrogenase is associated with impaired lung function: NHANES 2011-2012.
PLoS ONE, 2023 BackgroundSerum lactate dehydrogenase levels reflect disease status in a variety of organs, but its role in indicating pulmonary function is not yet clear.
Sheng Hu +9 more
doaj +1 more source
Pakistan Armed Forces Medical Journal, 2021 Objective: To study the diagnostic utility of lactate dehydrogenase levels in differentiating megaloblastic anemia from myelodysplastic anemia in Pakistan. Study Design: Comparative cross-sectional study.
Faraz Ali Rana +5 more
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