Results 21 to 30 of about 229,589 (299)

Lactate dehydrogenase and glycerol-3-phosphate dehydrogenase cooperatively regulate growth and carbohydrate metabolism during Drosophila melanogaster larval development [PDF]

, 2019
The dramatic growth that occurs during Drosophila larval development requires rapid conversion of nutrients into biomass. Many larval tissues respond to these biosynthetic demands by increasing carbohydrate metabolism and lactate dehydrogenase (LDH ...
Tennessen, Jason M., Pletcher, Rose C., Gosney, Chelsea J., Buddika, Kasun, Chawla, Geetanjali, Sterrett, Maria, Tennessen, Jason, Sokol, Nicholas Samuel, Burton, Anna K., Li, Hongde, Karty, Jonathan A., Julick, Cole R., Montooth, Kristi L., Sterrett, Maria C., Rai, Madhulika, Mahmoudzadeh, Nader H., Karty, Jonathan Allen, Sokol, Nicholas A., Luhur, Arthur   +18 more
core   +2 more sources

L-lactate exerts a pro-proliferative effect on adult hippocampal precursor cells in vitro

iScience, 2021
Summary: L-lactate has energetic and signaling properties, and its availability is modulated by activity-dependent stimuli, which also regulate adult hippocampal neurogenesis.
Alexandra Pötzsch, Sara Zocher, Stefanie N. Bernas, Odette Leiter, Annette E. Rünker, Gerd Kempermann   +5 more
doaj   +1 more source

Glycerol dehydrogenase: Structure, specificity, and mechanism of a family III polyol dehydrogenase [PDF]

, 2001
Background: Bacillus stearothermophilus glycerol dehydrogenase (GlyDH) (glycerol:NAD+ 2-oxidoreductase, EC 1.1.1.6) catalyzes the oxidation of glycerol to dihydroxyacetone (1,3-dihydroxypropanone) with concomitant reduction of NAD+ to NADH.
Baker PJ, Sveta Sedelnikova, Taylor R, Sedelnikova S, Baker, Patrick J., Rice DW, Muir, Nicola M., Gore, Michael G., Burke J, David W. Rice, Ruzheinikov, Sergey N., Bullough, Per A., Sedelnikova, Sveta, Sergey N. Ruzheinikov, Per A. Bullough, Patrick J. Baker, Gore MG, Burke, Jacky, Michael G. Gore, Muir NM, Bullough PA, Nicola M. Muir, Rice, David W., Robert Taylor, Ruzheinikov SN, Jacky Burke, Taylor, Robert   +26 more
core   +1 more source

L-(+)-lactate dehydrogenase deficiency is lethal in Streptococcus mutans [PDF]

Journal of Bacteriology, 1994
The previously cloned gene for L-(+)-lactate dehydrogenase (LDH) from Streptococcus mutans was mutagenized in vitro. An Escherichia coli transformant which expressed a thermolabile LDH activity was identified. The ldh(Ts) gene was introduced into S.
A, Chen, J D, Hillman, M, Duncan
openaire   +2 more sources

Elevated LDH greater than 400 U/L portends poorer overall survival in diffuse large B-cell lymphoma patients treated with CD19 CAR-T cell therapy in a real world multi-ethnic cohort

Experimental Hematology & Oncology, 2021
Anti-CD19 chimeric antigen receptor T-cell therapies have shown striking clinical activity in diffuse large B-cell lymphoma but robust biomarkers predictive of responsiveness are still needed.
Emma Rabinovich, Kith Pradhan, R. Alejandro Sica, Lizamarie Bachier-Rodriguez, Ioannis Mantzaris, Noah Kornblum, Aditi Shastri, Kira Gritsman, Mendel Goldfinger, Amit Verma, Ira Braunschweig   +10 more
doaj   +1 more source

Lactate dehydrogenase supports lactate oxidation in mitochondria isolated from different mouse tissues

Redox Biology, 2020
Research over the past seventy years has established that mitochondrial-l-lactate dehydrogenase (m-L-LDH) is vital for mitochondrial bioenergetics. However, in recent report, Fulghum et al.
Adrian Young, Catherine Oldford, Ryan J. Mailloux   +2 more
doaj   +1 more source

Serum lactate dehydrogenase is associated with impaired lung function: NHANES 2011-2012.

PLoS ONE, 2023
BackgroundSerum lactate dehydrogenase levels reflect disease status in a variety of organs, but its role in indicating pulmonary function is not yet clear.
Sheng Hu, Jiayue Ye, Qiang Guo, Sheng Zou, Wenxiong Zhang, Deyuan Zhang, Yang Zhang, Silin Wang, Lang Su, Yiping Wei   +9 more
doaj   +1 more source

Changes in milk L-lactate, lactate dehydrogenase, serum albumin, and IgG during milk ejection and their association with somatic cell count [PDF]

, 2015
In both conventional and automatic milking systems (AMS), sensitive and reliable mastitis detection is important for profitable milk production. Mastitis detection parameters must be able to detect mastitis when the somatic cell count (SCC) is only ...
Wall-Villez, Samantha Kay, Lehmann, M, Bruckmaier, Rupert, Wellnitz, Olga, Wellnitz, O, Lehmann, Mirjam, Wall, S K, Bruckmaier, R M   +7 more
core   +1 more source

Lactate dehydrogenase in the cyanobacterium Microcystis PCC7806 [PDF]

, 1995
The cyanobacterium Microcystis PCC7806 was found to possess an NAD-dependent lactate dehydrogenase (EC 1.1.1.27) which catalyzes the reduction of pyruvate to l-lactate.
Moezelaar, R., Stal, L.J., Teixeira, M.J., de   +2 more
core   +3 more sources

Crystallization and preliminary x-ray diffraction analysis of L-threonine dehydrogenase (TDH) from the hyperthermophilic archaeon Thermococcus kodakaraensis [PDF]

, 2008
The enzyme L-threonine dehydrogenase catalyses the NAD(+)-dependent conversion of L-threonine to 2-amino-3-ketobutyrate, which is the first reaction of a two-step biochemical pathway involved in the metabolism of threonine to glycine.
Jamil, F., Erskine, P.T., P. T. Erskine, J. N. Wright, F. Jamil, N. Rashid, Bowyer, A., H. Mikolajek, Q. Bashir, Akhtar, M., A. Coker, M. Akhtar, Rashid, N., J. B. Cooper, Cooper, J.B., Coker, A., Bashir, Q., Wright, J.N., Mikolajek, H., A. Bowyer   +19 more
core   +1 more source