Results 11 to 20 of about 33,795 (256)

Microbial Biosynthesis of L-Malic Acid and Related Metabolic Engineering Strategies: Advances and Prospects [PDF]

Frontiers in Bioengineering and Biotechnology, 2021
Malic acid, a four-carbon dicarboxylic acid, is widely used in the food, chemical and medical industries. As an intermediate of the TCA cycle, malic acid is one of the most promising building block chemicals that can be produced from renewable sources ...
Zhen Wei, Yongxue Xu, Qing Xu, Wei Cao, Wei Cao, He Huang, Hao Liu, Hao Liu   +7 more
doaj   +2 more sources

Production of L-Malic Acid by Metabolically Engineered Aspergillus nidulans Based on Efficient CRISPR–Cas9 and Cre-loxP Systems [PDF]

Journal of Fungi, 2023
Aspergillus nidulans has been more extensively characterized than other Aspergillus species considering its morphology, physiology, metabolic pathways, and genetic regulation.
Ziqing Chen, Chi Zhang, Lingling Pei, Qi Qian, Ling Lu   +4 more
doaj   +2 more sources

Optimization of l-malic acid production from acetate with Aspergillus oryzae DSM 1863 using a pH-coupled feeding strategy [PDF]

Microbial Cell Factories, 2022
Background Malic acid, a dicarboxylic acid mainly used in the food industry, is currently produced from fossil resources. The utilization of low-cost substrates derived from biomass could render microbial processes economic.
Aline Kövilein, Vera Aschmann, Lena Zadravec, Katrin Ochsenreither   +3 more
doaj   +2 more sources

The Cardioprotective Effects of Citric Acid and L-Malic Acid on Myocardial Ischemia/Reperfusion Injury [PDF]

Evidence-Based Complementary and Alternative Medicine, 2013
Organic acids in Chinese herbs, the long-neglected components, have been reported to possess antioxidant, anti-inflammatory, and antiplatelet aggregation activities; thus they may have potentially protective effect on ischemic heart disease. Therefore, this study aims to investigate the protective effects of two organic acids, that is, citric acid and ...
Tang, Xilan, Liu, Jianxun (R17789), Dong, Wei, Li, Peng, Li, Lei, Lin, Chengren, Zheng, Yongqiu, Hou, Jincai, Li, Dan   +8 more
openaire   +4 more sources

From beet molasses to malic acid: holistic development of fermentation and downstream process [PDF]

Biotechnology for Biofuels and Bioproducts
Background The growing demand for sustainable alternatives to fossil-based chemicals has increased interest in platform chemicals derived from renewable biomass sources, such as malic acid.
Luca Antonia Grebe, Christina Maria Krekel, Constantin Alexander Maaß, Mario Beckers, Martin Smotrycki, An N. T. Phan, Lars M. Blank, Katharina Saur, Marcel Mann, Jörn Viell, Andreas Jupke, Jørgen Barsett Magnus   +11 more
doaj   +2 more sources

Identification of candidate genes for malic acid content in tomato fruits and development of associated SNP markers [PDF]

Frontiers in Plant Science
Malic acid is one of the major organic acids in tomato (Solanum lycopersicum L.) fruit and plays a critical role in flavor and overall fruit quality. Identifying genes associated with malic acid accumulation and elucidating their genetic mechanisms can ...
Shanshan Wang, Chenyu Wang, Ximeng Wei, Lijuan Qie, Ainong Shi, Qingzhen Yin   +5 more
doaj   +2 more sources

Addition of Organic Acids and Lactobacillus acidophilus to the Leguminous Forage Chamaecrista rotundifolia Improved the Quality and Decreased Harmful Bacteria of the Silage

Animals, 2022
This study aimed to investigate the effects of citric acid, malic acid, and Lactobacillus acidophilus (L) on fermentation parameters and the microbial community of leguminous Chamaecrista rotundifolia silage. Fresh C. rotundifolia was treated without any
Qixian Feng, Wenjiao Shi, Siqi Chen, Abraham Allan Degen, Yue Qi, Fulin Yang, Jing Zhou   +6 more
doaj   +1 more source

Malic Acid Production by Aspergillus Oryzae: The Role of CaCO3

Chemical Engineering Transactions, 2018
This study investigated the malic acid production capability of Aspergillus oryzae NRRL 3488 with three different CaCO3 concentrations, 20 g/L, 80 g/L, and 120 g/L, used as pH buffers and CO2 supply.
Monique Geyer, Faith M. Onyancha, Willie Nicol, Hendrik G. Brink   +3 more
doaj   +1 more source

Microbial Production of Malic Acid from Biofuel-Related Coproducts and Biomass

Fermentation, 2017
The dicarboxylic acid malic acid synthesized as part of the tricarboxylic acid cycle can be produced in excess by certain microorganisms. Although malic acid is produced industrially to a lesser extent than citric acid, malic acid has industrial ...
Thomas P. West
doaj   +1 more source

Variation of nutritional requirements of Leuconostoc oenos by organic acids

OENO One, 1993
Leuconostoc oenos strains: m, L2 ST, X2L, have been isolated from different Argentinian red wines. Amino acids, vitamins and base requirements were determined in a synthetic medium containing L-malic acid, citric acid or both organic acids. The organisms
María Julia Amoroso, Fabiana María Saguir, María Cristina Manca de Nadra   +2 more
doaj   +1 more source