Results 191 to 200 of about 33,795 (256)

Green manufacturing of amoxicillin trihydrate: a malic acid-assisted crystallization framework enhanced by Taguchi-ANN optimization. [PDF]

RSC Adv
Ergin MF, Yaşa H, Çelik Onar H.
europepmc   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Organic acids induce plant defense responses and suppress root-knot nematodes in tomato via molecular mechanisms and molecular docking insights. [PDF]

Sci Rep
Adss IA, El-Habashy DE, Hafez EE, ELKobrosy DH, El-Ansary RE, Hammad MA, El-Sayed GM.   +6 more
europepmc   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

IL‐7R‐Enriched Extracellular Vesicles From the Thymus Drive Colitis via Promoting Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao, Yuheng Liu, Ruibing Yang, Zifeng Zhu, Junwei Wu, Dinghao Li, Jin Su, Yingxin He, Shiqi Luo, Feiyang Cao, Haiyi Deng, Lanmengxi Yang, Ling Zhong, Peiying Peng, Xinyi Wu, Chunmei Cai, Zhen Li, Yujin Wu, Shuofeng Zhu, Jie Wei, Yi Yang, Lifu Wang   +21 more
wiley   +1 more source

Anthocyanin Encapsulation as a Potential Approach for Improving the Quality of Aronia Powder. [PDF]

Molecules
Vidović S, Vasiljević MR, Ambrus R, Nastić N, Nikolić NĆ, Janković T, Gavarić A.   +6 more
europepmc   +1 more source

A new isolated fungus Talaromyces sp. MC-F2 efficiently solubilizes phosphate through media-dependent metabolic regulation. [PDF]

Sci Rep
Xia M, Bao P, He S, Qiu G, Zeng W, He Y.
europepmc   +1 more source

Integrated Chemical Profiling, Serum Pharmacochemistry, and Network Pharmacology to Elucidate the Anti-Hyperlipidemic Effects of <i>Rosa laxa</i> Retz. Fruits from Different Geographical Origins. [PDF]

Metabolites
He Y, Feng Q, Zhao W, Tian L.
europepmc   +1 more source

Predicting and Rationalizing Piezoelectricity in Racemic Bioorganic Molecular Crystals. [PDF]

Angew Chem Int Ed Engl
Vishnoi S, Guerin S.
europepmc   +1 more source

1H-NMR-based metabolomics reveals that prior exercise modulates metabolic changes in the cerebral cortex and hippocampus in sleep-deprived mice. [PDF]

Braz J Med Biol Res
Silva BRDD, Nunes PIG, Matos RS, Silva LMA, Alves Filho EG, Brito ES, Bruin PFC, Bruin VMS.   +7 more
europepmc   +1 more source