Results 81 to 90 of about 69,834 (346)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CHEMICAL COMPOSITION OF SOME AUTOCHTHONOUS FRUIT SPECIES FROM MACEDONIA

Journal of Agriculture and Plant Sciences
The scope of this paper is determination of the content of soluble dry matters, total sugar, total acids, invert sugar and citric, malic, tartaric and lactic acid in some autochthonous fruit species: pomegranate (Zumnarija, Bejnarija, Valandovska kisela,
Ana Selamovska, Milena Taseska-Gjorgjijevski, Aleksandar Markovski, Biljana Korunoska   +3 more
doaj   +1 more source

Effect of Biofilm Formation by Lactobacillus plantarum on the Malolactic Fermentation in Model Wine

Foods, 2020
Biofilm life-style of Lactobacillus plantarum (L. plantarum) strains was evaluated in vitro as a new and suitable biotechnological strategy to assure L-malic acid conversion in wine stress conditions. Sixty-eight L.
Gianfranco Pannella, Silvia Jane Lombardi, Francesca Coppola, Franca Vergalito, Massimo Iorizzo, Mariantonietta Succi, Patrizio Tremonte, Caterina Iannini, Elena Sorrentino, Raffaele Coppola   +9 more
doaj   +1 more source

Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism. [PDF]

, 2017
Malignant transformation is often accompanied by significant metabolic changes. To identify drivers underlying these changes, we calculated metabolic flux states for the NCI60 cell line collection and correlated the variance between metabolic states of ...
Bordbar, Aarash, Corbett, Austin J, Jamshidi, Neema, Palsson, Bernhard O, Thomas, Alex, Zielinski, Daniel C   +5 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Improving Organic Acid Secretion of Aspergillus niger by Overexpression C4-Dicarboxylic Acid Transporters

Fermentation
C4-dicarboxylic acids are essential organic compounds characterized by a four-carbon structure and two carboxyl groups. Their export from cells is mediated by specialized transporter proteins known as C4-dicarboxylic acid transporters (DCTs).
Yiyang Tan, Shutong Liu, Sheng Wu, Xiaolu Wang, Depei Wang, Xianli Xue   +5 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

l-Malic Acid Effect on Organic Acid Profiles and Fermentation By-products in Apple Wines

Czech Journal of Food Sciences, 2009
Industrial wine yeasts Saccharomyces bayanus and two interspecies hybrids (S. cerevisiae × S. bayanus) were checked for their suitability for fermentation of apple musts with different L-malic acid content (4, 7 and 11 g/l).
A. Kunicka-Styczyńska, E. Pogorzelski
doaj   +1 more source

Synthesis of erythro-L-.BETA.-Hydroxyglutamic Acid Hydrochloride from L-Malic Acid.

Chemical and Pharmaceutical Bulletin, 1992
Facile synthesis of erythro-L-β-hydroxyglutamic acid and its derivative, (2S, 3S)-3-acetoxypyroglutamate, from L-malimide is described. The Key reaction for the synthesis of 3-oxypyroglutamyl intermediate was the furylation of N-acylaminal acetate using zinc bromide-trimethylchlorosilane as an effective catalyst system.
Sojiro SHIOKAWA, Tomihisa OHTA, Shigeo NOZOE   +2 more
openaire   +2 more sources

Acetaldehyde metabolism by wine lactic acid bacteria and its oenological implications : a thesis presented in fulfillment of the requirements for the degree of Master of Science in Microbiology at Massey University [PDF]

, 2000
Acetaldehyde is one of the most important sensory carbonyl compounds formed during vinification. Excess acetaldehyde can adversely affect the flavour of wine and acetaldehyde plays a role in the colour development of red wines.
Osborne, James
core