Results 121 to 130 of about 714,437 (290)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Эндотелиопротективное действие комбинации тиоктовой кислоты с розувастатином при L-NAME-индуцированном дефиците оксида азота [PDF]

open access: yes, 2014
Изучение эндотелиопротективных свойств а-липоевой кислоты в таблетированной форме -тиоктацид БВ и ее сочетания с гиполипидемическим препаратом из группы статинов - розувастин, как одной из возможных эффективных комбинаций при дисфункции ...
Корокин, М. В.   +5 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

L-Arginine-No System Participates in the Analgesic Effect of Flunixin Meglumine in the Rat

open access: yesActa Veterinaria, 2016
This study investigated whether the L-arginine-NO system participates in the analgesic effect of flunixin meglumine in the rat. Hyperalgesia was induced by intraplantar (i.pl.) administration of carrageenan (500 μg) into the rat’s hind paw.
Milovanović Mirjana   +4 more
doaj   +1 more source

Chronic alpha1-adrenergic blockade improves hypertension and renal injury in L-NAME and low-renin L-NAME-DOCA hypertensive rats.

open access: yesMedical science monitor : international medical journal of experimental and clinical research, 2003
The present study investigated the contribution of alpha1-adrenergic blockade to hypertension induced by long-term blockade of nitric oxide and chronic treatment with deoxycorticosterone acetate (DOCA), which produced a low renin model of hypertension. We studied the effects of chronic administration of prazosin, an alpha1-receptor antagonist, on blood
Rosemary, Wangensteen   +4 more
openaire   +1 more source

Evaluation of SST-2 Role in LVH Regression Obtained in Hypertensive Mice Models After Blocking Renin-Angiotensin System [PDF]

open access: yes, 2019
Soluble ST2, is a protein which acts as a decoy receptor for interleukin-33, and served as biomarker associated with left ventricular hypertrophy (LVH). Few data exist in evaluating the effects of anti-hypertensive agents on the role-played form ST2 on ...
Hijriani, N. (Nursela)   +7 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Использование дитиокарбаматов при L-NAME индуцированном дефиците оксида азота [PDF]

open access: yes, 2012
Рассматриваются эндотелиопротективные свойства синтетических доноров оксида азота, относящихся к группе дитиокарбаматов (RE 1-418, RE 1-419, RE 1-420, OBR 3-121), предоставленных Российским научным центром по антибиотикам, (РНЦА) г ...
Арустамова, А. А.   +3 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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