Применение рекомбинантного эритропоэтина для фармакологической коррекции L-name индуцированной эндотелиальной дисфункции [PDF]
, 2012 Изучается влияние рекомбинантного эритропоэтина на эндотелиальную дисфункцию при N-нитро-L-аргинин метилового эфира (L-NAME) индуцированном дефиците оксида ...
Арустамова, А. А. +3 more
core
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
A fogbél válaszreakcióinak, kompenzáló mechanizmusainak vizsgálata patkányfogak pulpális erein vitálmikroszkópos modellen = Examination of pulps reaction and compensatory mechanism on rat dental pulp vessels on vitalmicroscopic model [PDF]
, 2007 A patkánymetszőfog-pulpa vitálmikroszkópos modellje optimális az inicialis toxicitás okozta pulpális változások kimutatására. Kísérleteinkben a self-etch adhezívek hatására bekövetkező akut változásokat vizsgáltuk.
Fejérdy, László +4 more
core
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
بررسی اثر نيتريک اکسايد روی عضله صاف حلقوی پيلور جنين موش صحرايی [PDF]
, 2004 نيتريک اکسايد( NO ) مولکول کوچک تقريباً ناپايدار و راديکال آزاد چربی دوستی است که توسط سلولهای متفاوت پستانداران ساخته میشود و در بدن آنها دارای اعمال متفاوتی از جمله واسطه عصبی و اثر سيتوتوکسيک میباشد.
ثقهالاسلام, معصومه +3 more
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Эндотелиопротекторное действие милдроната и его производных при моделировании L-NAME индуцированного дефицита оксида азота [PDF]
, 2011 Результаты исследования 4 химических производных пропионата на лабораторных крысахyesБелгородский государственный ...
Даниленко, Л. М. +4 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Изучение эффектов сочетанного применения эналаприла и лозартана с милдронатом при L-NAME-индуцированной эндотелиальной дисфункции [PDF]
, 2011 Результаты изучения эндотелио- и кардиопротективных эффектов милдроната, эналаприла, лозартана и их комбинации при L-NAME-индуцированной эндотелиальной дисфункции у самцов белых крысyesКурский государственный медицинский ...
Дронова, Т. А. +4 more
core +1 more source