Results 161 to 170 of about 713,418 (262)

L-NAME Administration Enhances Diabetic Kidney Disease Development in an STZ/NAD Rat Model. [PDF]

Int J Mol Sci, 2021
Corremans R, D'Haese PC, Vervaet BA, Verhulst A.   +3 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Entrevistando Homens Gays: Espaços do Armário, Protocolos de Sensibilidade e Cuidado Narrativo

Revista Latino-Americana de Geografia e Gênero
L. NAME, O. F. CARRILLO
doaj   +1 more source

Antihypertensive Effect of a Self-Microemulsifying System Obtained from an Ethanolic Extract of <i>Heliopsis longipes</i> Root in Spontaneously and L-NAME-Induced Hypertensive Rats. [PDF]

Molecules
Marrero-Morfa D, Luz-Martínez BA, Luna-Vázquez FJ, Quirino-Barreda CT, Rojas-Molina I, García-Servín M, Vázquez-Landaverde PA, Ruiz-Castillo V, Ibarra-Alvarado C, Rojas-Molina A.   +9 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Nanoformulation of valsartan-loaded tablet attenuates L-NAME-induced hypertension: role of Nrf2/PPARγ/AT1 signaling pathway. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Elimam H, El-Say KM, Ahmed TA, Marleau S, El-Khayat Z, El-Banna M, Hussein J.   +6 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Pravastatin Mitigates Hypertension, Proteinuria, and Fetal Growth Restriction in an L-NG-Nitro Arginine Methyl Ester (L-NAME)-Induced Rat Model of Preeclampsia. [PDF]

Cureus
Elamin HA, Saeed AM, Sharif MM, ElMahdi A.   +3 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Antihypertensive Effects of Lotus Seed (<i>Nelumbo nucifera</i> Gaertn.) Extract via eNOS Upregulation and Oxidative Stress Reduction in L-NAME-Induced Hypertensive Rats. [PDF]

Pharmaceuticals (Basel)
Inchan A, Bualeong T, Kaewkong W, Nuengchamnong N, Apaikawee P, Sa-Nguanpong P, Sumsakul W, Charoenphon N, Chatturong U, Deetud W, Chootip K.   +10 more
europepmc   +1 more source