Results 171 to 180 of about 714,437 (290)

Pulegone Prevents Hypertension through Activation of Muscarinic Receptors and Cyclooxygenase Pathway in L-NAME-Induced Hypertensive Rats. [PDF]

Cardiovasc Ther, 2023
Razzaq MA, Younis W, Malik MNH, Alsahli TG, Alamgeer, Jahan S, Ehsan R, Gasparotto Junior A, Bashir A.   +8 more
europepmc   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

UNI-494 treatment improves measures of renal dysfunction and cardiac pathology in male rats receiving L-NAME and angiotensin II. [PDF]

Physiol Rep
Ho FJM, Siow CJR, Aljaibeji H, Ding M, Mitchell RN, Medicherla S, Reddy G, Gupta S, Williams GH, Romero JR.   +9 more
europepmc   +1 more source

The L-NAME mouse model of preeclampsia and impact to long-term maternal cardiovascular health. [PDF]

Life Sci Alliance, 2022
de Alwis N, Binder NK, Beard S, Mangwiro YT, Kadife E, Cuffe JS, Keenan E, Fato BR, Kaitu'u-Lino TJ, Brownfoot FC, Marshall SA, Hannan NJ.   +11 more
europepmc   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Aqueous extract of Peristrophe bivalvis leaf alleviates oxidative stress in L-NAME-induced hypertensive rats. [PDF]

BMC Complement Med Ther
Aluko EO, Oyeyemi WA, Fasanmade AA.
europepmc   +1 more source

The role of ferritin and iron dextran in exacerbating preeclampsia in an L-NAME-treated rat model. [PDF]

Ann Transl Med, 2022
Zhu X, Jiang R, Ying X, Li Z, Jiang P.
europepmc   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

<i>Theobroma cacao</i> seed extracts attenuate dyslipidemia and oxidative stress in L-NAME induced hypertension in Wistar rats. [PDF]

Int J Med Sci
Agwupuye EI, Agboola AR, Kuo YC, Itam AH, Ezeayinka LU, Atangwho IJ, Ayeyemi BM, Edema AA, Lawal B, Alotaibi MO, Almohmadi NH, Batiha GE, El-Sabbagh NM, Huang HS.   +13 more
europepmc   +1 more source

Dual thick and thin filament linked regulation of stretch- and L-NAME-induced tone in young and senescent murine basilar artery. [PDF]

Front Physiol, 2023
Lubomirov LT, Schroeter MM, Hasse V, Frohn M, Metzler D, Bust M, Pryymachuk G, Hescheler J, Grisk O, Chalovich JM, Smyth NR, Pfitzer G, Papadopoulos S.   +12 more
europepmc   +1 more source