Results 191 to 200 of about 729,292 (310)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Retraction: Neuroprotective Role of L-NG-Nitroarginine Methyl Ester (L-NAME) against Chronic Hypobaric Hypoxia with Crowding Stress (CHC) Induced Depression-Like Behaviour. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Antihypertensive Activity of Milk Fermented by Lactiplantibacillus plantarum SR37-3 and SR61-2 in L-NAME-Induced Hypertensive Rats [PDF]

Foods, 2022
Yuan L, Li Y, Chen M, Xue L, Wang J, Ding Y, Zhang J, Wu S, Ye Q, Zhang S, Yang R, Zhao H, Wu L, Liang T, Xie X, Wu Q.   +15 more
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Decreased blood pressure with acute administration of quercetin in L-NAME-induced hypertensive rats. [PDF]

Basic Clin Pharmacol Toxicol
Mkhize SA, Nthlane RA, Xhakaza SP, Verhaert PD, Baijnath S, Millen AME, Michel FS.   +6 more
europepmc   +1 more source

Effects of Mineralocorticoid Receptor Blockade and Statins on Kidney Injury Marker 1 (KIM-1) in Female Rats Receiving L-NAME and Angiotensin II. [PDF]

Int J Mol Sci, 2023
Huang J, Caliskan Guzelce E, Gholami SK, Gawelek KL, Mitchell RN, Pojoga LH, Romero JR, Williams GH, Adler GK.   +8 more
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

TRPC6 Deficiency Attenuates Mitochondrial and Cardiac Dysfunction in Heart Failure with Preserved Ejection Fraction Induced by High-Fat Diet Plus L-NAME. [PDF]

Int J Mol Sci
Li X, Fu Y, Dai X, do Carmo JM, da Silva AA, Mouton AJ, Omoto ACM, Spitz RW, Wang L, Hall JE, Wang Z.   +10 more
europepmc   +1 more source

Phytochemical characterization, antioxidant activity and antihypertensive evaluation of <i>Ocimum basilicum</i> L. in l-NAME induced hypertensive rats and its correlation analysis. [PDF]

Heliyon, 2023
Qamar F, Sana A, Naveed S, Faizi S.
europepmc   +1 more source

Метаболическая и антиоксидантная терапия L-NAME-индуцированной эндотелиальной дисфункции

Кубанский научный медицинский вестник, 2008
The carried out experimental investigations allow to conclude that the preparations cardionat of 80 mg/kg dose and mexicor of 30 mg/kg dose rendered expressed endothelioprotective action on the model of L-NAME-induced deficiency of NO, what was evident in the prevalence of endotheliodependent vessel relaxation and decrease of endothelium dysfunction ...
openaire   +1 more source