Results 81 to 90 of about 714,437 (290)

Эндотелиопротективные эффекты тетрагидробиоптерина и L-аргинина [PDF]

, 2012
Рассматривается эндотелиопротективные эффекты тетрагидробиоптерина, L-аргинина и их комбинации на ADMA-подобной, L-NAME- индуцированной и гипергомоцистеин-индуцированной моделях эндотелиальной ...
Арустамова, А. А., Гудырев, О. С., Корокин, М. В., Корокина, Л. В., Саввин, В. А.   +4 more
core  

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

The Comparison Effect of DOCA and L-NAME on T Cells Activation in the Preeclampsia Mice Model

Journal of Experimental Life Science
Preeclampsia is a systemic disorder of pregnancy characterized by the maternal immune system's failure to properly adapt to fetal antigens, resulting in chronic inflammatory responses.
Riska Amalia Khodijah, Yuyun Ika Christina, Dinia Rizqi Dwijayanti, Sri Rahayu, Muhaimin Rifa’i, Muhammad Sasmito Djati   +5 more
doaj   +1 more source

L-NAME releases nitric oxide and potentiates subsequent nitroglycerin-mediated vasodilation

Redox Biology, 2019
L-NG-Nitro arginine methyl ester (L-NAME) has been widely applied for several decades in both basic and clinical research as an antagonist of nitric oxide synthase (NOS).
Taiming Liu, Meijuan Zhang, George T. Mukosera, Dan Borchardt, Qian Li, Trent E. Tipple, Abu Shufian Ishtiaq Ahmed, Gordon G. Power, Arlin B. Blood   +8 more
doaj   +1 more source

Морфологические изменения сердечно-сосудистой системы при моделировании L-NAME индуцированной эндотелиальной дисфункции в течение 28 дней [PDF]

, 2012
Изучение морфологических изменений сердечно-сосудистой системы в результате развития эндотелиальной дисфункции на 28-дневной модели L-NAME-индуцированного дефицита оксида ...
Белоус, А. С.
core   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Role of Atrial Natriuretic Peptide in Oxytocin Induced Cardioprotection [PDF]

, 2015
Background The purpose of this study was to determine whether endogenous atrial natriuretic peptide (ANP) contributes to the protective effect of neurohypophysial hormone oxytocin (OT) in heart preconditioning.
Faghihi, Mahdieh., Houshmand, Fariba., Zahediasl, Saleh.   +2 more
core   +1 more source

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source

Nitric oxide modulates the cardiovascular effects elicited by acetylcholine in the NTS of awake rats [PDF]

, 2008
da Silva LG, Rodrigues Dias AC, Furlan E, Colombari E. Nitric oxide modulates the cardiovascular effects elicited by acetylcholine in the NTS of awake rats. Am J Physiol Regul Integr Comp Physiol 295: R1774-R1781, 2008. First published September 24, 2008;
Colombari, Eduardo, Dias, Ana Carolina Rodrigues, Furlan, Elaina, Silva, Liana Gouveia da   +3 more
core   +1 more source