L-serine: Neurological Implications and Therapeutic Potential [PDF]
Biomedicines, 2023 L-serine is a non-essential amino acid that plays a vital role in protein synthesis, cell proliferation, development, and sphingolipid formation in the central nervous system.
Soe Maung Maung Phone Myint, Liou Y. Sun
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Effects of l-Serine on Macrolide Resistance in Streptococcus suis [PDF]
Microbiology Spectrum, 2022 Streptococcus suis is an important zoonotic pathogen. Due to the indiscriminate use of macrolides, S. suis has developed a high level of drug resistance, which has led to a serious threat to human and animal health.
Tong Wu +7 more
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Enhanced l-serine synthesis in Corynebacterium glutamicum by exporter engineering and Bayesian optimization of the medium composition [PDF]
Synthetic and Systems Biotechnologyl-serine is a versatile, high value-added amino acid, widely used in food, medicine and cosmetics. However, the low titer of l-serine has limited its industrial production.
Yifan Huang +10 more
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Metabolic engineering of an industrial bacterium Zymomonas mobilis for anaerobic l-serine production [PDF]
Synthetic and Systems BiotechnologyDue to the complicated metabolic and regulatory networks of l-serine biosynthesis and degradation, microbial cell factories for l-serine production using non-model microorganisms have not been reported.
Zhen Wang +8 more
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Electrochemical Detection of Olivetol Based on Poly(L-Serine) Film Layered Copper Oxide Modified Carbon Paste Electrode (p-L-Serine/CuO/CPE) [PDF]
Nanomaterials, 2022 Olivetol is an important polyphenol compound and intermediate in the synthesis of cannabinoids possessing many types of biological activities. A facile electrochemical sensor for olivetol was fabricated based on p-L-serine, and copper oxide (CuO ...
Zongyi You +3 more
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Intra-Brain and Plasma Levels of L-Serine Are Associated with Cognitive Status in Patients with Chronic Kidney Disease [PDF]
Kidney Diseases, 2023 Introduction: The number of patients with chronic kidney disease (CKD) is increasing worldwide. Cognitive impairment is one of the comorbidities of CKD.
Yasunori Iwata +21 more
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L-serine metabolic regulation and host respiratory homeostasis [PDF]
Frontiers in Cellular and Infection MicrobiologyL-Serine, a non-essential amino acid (NEAA), can be obtained through diet or in situ synthesis. Functionally, L-serine not only serves as the precursor of other amino acids, lipids, and nucleotides, but also participates in the folate/methionine cycle ...
Pan Li +5 more
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Separation and detection of D-/L-serine by conventional HPLC [PDF]
MethodsX, 2022 D-serine has a role as an endogenous allosteric agonist of N-methyl-D-aspartate (NMDA) receptor in the mammalian brain. In this study, we present a detailed description of our method that measures D-/L-serine by using conventional high performance liquid
Hiroki Shikanai +5 more
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L-Serine–Incorporated Collagen Scaffolds for Modulating In Vivo Degradation Behavior [PDF]
Journal of Functional BiomaterialsCollagen-based biomaterials are widely used, but their relatively rapid biodegradation can limit functional duration. Such collagen constructs are widely used as barrier membranes in guided tissue and bone regeneration, where controlled degradation is ...
Su-Young Kim +5 more
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L-serine at the crossroads of microbiota, intestinal health, and disorders [PDF]
Communications BiologyL-serine is an amino acid involved in maintaining intestinal mucosal homeostasis through its role in protein synthesis but also in redox balance, immune function and lipid metabolism.
Amandine Devaux +3 more
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