Improving l-serine formation by Escherichia coli by reduced uptake of produced l-serine [PDF]
Microbial Cell Factories, 2020 Background Microbial de novo production of l-serine, which is widely used in a range of cosmetic and pharmaceutical products, has attracted increasing attention due to its environmentally friendly characteristics.
Chenyang Wang +4 more
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Simplistic synthesis of L-Serine-ZnS composites with distinct morphological nature, enhanced thermal stability and superior photocatalytic enactment for ciprofloxacin removal [PDF]
Scientific ReportsL-Serine-ZnS composites were synthesized via a simple solvent casting approach by altering the quantity of added ZnS within a range of 1–5 wt%. The functions of the prepared L-Serine-ZnS composites as photocatalysts with superior performance were ...
Aimon Hossain Faisal +2 more
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Quercetin's antitumor effect in bladder cancer: Synergistic regulation of gut microbiota and l-serine metabolic pathway [PDF]
Acta Pharmaceutica Sinica BQuercetin is a bioflavonoid that is abundant and easy to extract, and has beneficial effects such as anti-cancer, anti-inflammatory, and antioxidant properties.
Zhao Zhai +15 more
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The role of l-serine and l-threonine in the energy metabolism and nutritional stress response of Trypanosoma cruzi [PDF]
mSpherel-Serine and l-threonine have versatile roles in metabolism. In addition to their use in protein synthesis, these amino acids participate in the biosynthesis pathways of other amino acids and even phospholipids.
Mayke Bezerra Alencar +6 more
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Exogenous L-Serine Alleviates Pasteurella multocida-Induced Inflammation by Reprogramming the Transcription and Metabolism of Macrophages [PDF]
Veterinary SciencesP. multocida is notorious for inducing excessive inflammation with high lethality in multiple animals, such as cattle, pigs, and chickens. Our previous study revealed that L-serine was decreased in the lungs of mice infected with P.
Fang He +7 more
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l-Serine links metabolism with neurotransmission [PDF]
Progress in Neurobiology, 2021 Brain energy metabolism is often considered as a succession of biochemical steps that metabolize the fuel (glucose and oxygen) for the unique purpose of providing sufficient ATP to maintain the huge information processing power of the brain. However, a significant fraction (10-15 %) of glucose is shunted away from the ATP-producing pathway (oxidative ...
Maugard, Marianne +3 more
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l-Serine in disease and development [PDF]
Biochemical Journal, 2003 The amino acid l-serine, one of the so-called non-essential amino acids, plays a central role in cellular proliferation. l-Serine is the predominant source of one-carbon groups for the de novo synthesis of purine nucleotides and deoxythymidine monophosphate.
De Koning, TJ +5 more
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Microorganisms, 2022 L-serine is widely used in the food, cosmetic, and pharmaceutical industries. However, the complicated metabolic network and regulatory mechanism of L-serine production lead to the suboptimal productivity of the direct fermentation of L-serine and limits
Chenyang Wang +5 more
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Pharmacokinetics of oral l-serine supplementation in a single patient
Molecular Genetics and Metabolism Reports, 2020 Serine, a non-essential amino acid, has attracted clinical attention because of potential benefit in certain metabolic and neurological disorders. Despite the therapeutic potential, little is known about the pharmacokinetics of l-serine metabolism in ...
Danny E. Miller +3 more
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Improvement in regional CBF by L-serine contributes to its neuroprotective effect in rats after focal cerebral ischemia. [PDF]
PLoS ONE, 2013 To investigate the mechanisms underlying the neuroprotective effect of L-serine, permanent focal cerebral ischemia was induced by occlusion of the middle cerebral artery while monitoring cerebral blood flow (CBF).
Tao-Jie Ren +7 more
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