Results 11 to 20 of about 346,828 (310)
Forskolin Regulates L-Type Calcium Channel through Interaction between Actinin 4 and β3 Subunit in Osteoblasts. [PDF]
PLoS ONE, 2015 Voltage-dependent L-type calcium channels that permit cellular calcium influx are essential in calcium-mediated modulation of cellular signaling. Although the regulation of voltage-dependent L-type calcium channels is linked to many factors including ...
Xuemei Zhang +6 more
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Frontiers in Pharmacology, 2021 Background: The current study presents the novel angiotensin II receptor blocker fluorophenyl benzimidazole (FPD) as an antihypertensive agent in the SHR model of hypertension.
Hina Iqbal +9 more
doaj +1 more source
Hydrogen sulfide regulates the colonic motility by inhibiting both L-type calcium channels and BKCa channels in smooth muscle cells of rat colon. [PDF]
PLoS ONE, 2015 To examine the hypothesis that hydrogen sulfide (H2S) regulates the colonic motility by modulating both L-type voltage-dependent calcium channels and large conductance Ca2+-activated K+ (BKCa) channels.Immunohistochemistry was performed on rat colonic ...
Xiaojing Quan +5 more
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Autoregulation of Cardiac l-Type Calcium Channels [PDF]
Trends in Cardiovascular Medicine, 2009 l-Type calcium channels (LTCCs) are major contributors to electrical and contractile function of the heart. They regulate action potential duration, enable calcium entry into cardiac myocytes for contraction, and regulate growth-related signaling in the heart.
Jonathan, Satin, Elizabeth A, Schroder
openaire +2 more sources
Functional Importance of L- and P/Q-Type Voltage-Gated Calcium Channels in Human Renal Vasculature [PDF]
, 2011 Calcium channel blockers are widely used for treatment of hypertension, because they decrease peripheral vascular resistance through inhibition of voltage-gated calcium channels.
Cribbs, Leanne L +6 more
core +1 more source
Cellular Physiology and Biochemistry, 2015 Background/Aims: Arachidonic acid (AA) and its metabolites are important endogenous lipid messengers. In this study, we test the effect of Leukotriene B4 (LTB4), a 5-lipoxygenase metabolite of AA, on L-type calcium channels in A7r5 rat aortic vascular ...
Xiaoyu Liu +4 more
doaj +1 more source
Ryanodine Receptors Selectively Interact with L Type Calcium Channels in Mouse Taste Cells. [PDF]
PLoS ONE, 2013 INTRODUCTION:WE REPORTED THAT RYANODINE RECEPTORS ARE EXPRESSED IN TWO DIFFERENT TYPES OF MAMMALIAN PERIPHERAL TASTE RECEPTOR CELLS: Type II and Type III cells. Type II cells lack voltage-gated calcium channels (VGCCs) and chemical synapses.
Michelle R Rebello +2 more
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Interactions of short-term and chronic treadmill training with aging of the left ventricle of the heart [PDF]
, 2015 With aging, there is a decline in cardiac function accompanying increasing risk of arrhythmias. These effects are likely to be mechanistically associated with age-associated changes in calcium regulation within cardiac myocytes.
Close, Graeme L. +6 more
core +2 more sources
T-type calcium channel: a privileged gate for calcium entry and control of adrenal steroidogenesis
Frontiers in Endocrinology, 2016 Intracellular calcium plays a crucial role in modulating a variety of functions such as muscle contraction, hormone secretion, gene expression or cell growth. Calcium signaling has been however shown to be more complex than initially thought.
Michel Florian Rossier +1 more
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Pharmaceutical Biology, 2022 Context Solanaceae glycoalkaloids (SGAs) possess cardiomodulatory activity.Objective This study investigated the potential interaction between verapamil and glycoalkaloids.Material and methods The cardioactivity of verapamil and glycoalkaloids (α ...
Szymon Chowański +9 more
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