Results 21 to 30 of about 20,375,518 (297)
Circulation Research, 2002 Voltage-gated calcium channels are essential for coupling membrane depolarization to the influx of calcium in all excitable cells. The calcium that flows into excitable cells through voltage-gated calcium channels serves a dual function, generating both electrical and chemical signals. The intracellular events controlled by calcium are diverse and many.
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Indonesian Biomedical Journal, 2020 BACKGROUND: Iron-overload cardiomyopathy (IOC) is a major comorbidity in patients with chronic repetitive blood transfusion due to myocardial iron uptake that facilitated by calcium channels.
Mas Rizky Anggun Adipurna Syamsunarno +6 more
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Acta Neuropathologica Communications, 2019 Perioperative sleep disturbance is a risk factor for persistent pain after surgery. Clinical studies have shown that patients with insufficient sleep before and after surgery experience more intense and long-lasting postoperative pain.
Qi Li +9 more
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Neurobiology of Disease, 2000 Organic calcium channel antagonists block epileptiform activity in adult tissue, suggesting an essential role of L-type channels in epileptogenesis in the mature CNS.
R. Köhling, H. Straub, E.-J. Speckmann
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Toxics, 2022 Tetrabromobisphenol A (TBBPA) is a flame retardant widely used to reduce flammability. It is an endocrine disruptor, and due to constant human exposure, some concerns have been raised regarding its impact on human health.
Joana Feiteiro +4 more
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Stem Cell Reports, 2018 Summary: The absence of FMR1 protein (FMRP) causes fragile X syndrome (FXS) and disturbed FMRP function is implicated in several forms of human psychopathology.
Claudia Danesi +9 more
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Psychostimulants, L-type Calcium Channels, Kinases, and Phosphatases [PDF]
The Neuroscientist, 2005 There is growing evidence for the role of voltage-gated L-type Ca 2+ channels in mediating aspects of the addictive properties of psychostimulants. L-type Ca 2+ channels activate Ca 2+ second-messenger pathways ...
Anjali M, Rajadhyaksha +1 more
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P/Q-type calcium-channel blockade in the periaqueductal gray facilitates trigeminal nociception: a functional genetic link for migraine? [PDF]
, 2002 The discovery of mis-sense mutations in the alpha1A subunit of the P/Q-type calcium channel in patients with familial hemiplegic migraine indicates the potential involvement of dysfunctional ion channels in migraine.
Goadsby, PJ +11 more
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Protein kinase A modulation of CaV1.4 calcium channels
Nature Communications, 2016 Phosphorylation of L-type calcium CaV channels by protein kinase A is essential for several physiological events. Here, the authors show how this kinase regulates CaV1.4 activity, suggesting a general regulatory mechanism for all L-type calcium channels.
Lingjie Sang, Ivy E. Dick, David T. Yue
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Weft, Warp & Weave: The Intricate Tapestry of Calcium Channels Regulating T Lymphocyte Function
Frontiers in Immunology, 2013 Calcium (Ca2+) is a universal second messenger important for T lymphocyte homeostasis, activation, proliferation, differentiation and apoptosis. The events surrounding Ca2+ mobilization in lymphocytes are tightly regulated and involve the coordination of
Kyla D Omilusik +3 more
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