Results 31 to 40 of about 9,297 (211)
Revista da Sociedade Brasileira de Medicina Tropical, 1984 Um inquérito em cães realizado na região de Três Braços, Bahia, mostrou que 3,0% de 98 animais tinham amastigotas em lesões de pele. Parasitos não foram encontrados em pele normal da orelha.
Air C. Barretto +5 more
doaj +3 more sources
Frontiers in Cellular and Infection Microbiology, 2020 In this study, we generated a transgenic strain of Leishmania braziliensis, an etiological agent associated with a diversity of clinical manifestations of leishmaniasis ranging from localized cutaneous to mucocutaneous to disseminated disease. Transgenic
Rohit Sharma +9 more
doaj +1 more source
European Journal of Medicinal Chemistry Reports, 2022 Leishmaniasis is a neglected tropical disease, whose chemotherapy still presents a series of severe side effects for the patient. Recently, our group published the leishmanicidal action of 1,10-phenanthroline (1), 1,10-phenanthroline-5,6-dione (phendione,
André L.S. Santos +7 more
doaj +1 more source
Comparing the Antileishmanial Activity of Gold(I) and Gold(III) Compounds in L. amazonensis and L. braziliensis in Vitro [PDF]
ChemMedChem, 2020 AbstractAbstract: A series of mononuclear coordination or organometallic AuI/AuIII complexes (1–9) have been comparatively studied in vitro for their antileishmanial activity against promastigotes and amastigotes, the clinically relevant parasite form, of Leishmania amazonensis and Leishmania braziliensis.
Karen Minori +4 more
openaire +3 more sources
Intraspecies Polymorphisms in the Lipophosphoglycan of L. braziliensis Differentially Modulate Macrophage Activation via TLR4 [PDF]
Frontiers in Cellular and Infection Microbiology, 2019 Lipophosphoglycan (LPG) is the major Leishmania surface glycoconjugate having importance during the host-parasite interface. Leishmania (Viannia) braziliensis displays a spectrum of clinical forms including: typical cutaneous leishmaniasis (TL), mucocutaneous (ML), and atypical lesions (AL).
da Silva Vieira, Tamara +6 more
openaire +4 more sources
Leishmania infantum induces high phagocytic capacity and intracellular nitric oxide production by human proinflammatory monocyte [PDF]
Memorias do Instituto Oswaldo CruzBACKGROUND The mechanism of resistance to SbIII in Leishmania is complex, multifactorial and involves not only biochemical mechanisms, but also other elements, such as the immune system of the host.
Christiana Vargas Ribeiro +6 more
doaj +2 more sources
Frontiers in Cellular and Infection Microbiology, 2022 Patients with cutaneous leishmaniasis (CL) due to Leishmania braziliensis infection have an exacerbated inflammatory response associated with tissue damage and ulcer development.
Maurício T. Nascimento +22 more
doaj +1 more source
In vitro stimulation of metacyclogenesis in Leishmania braziliensis, L. donovani, L. major and L. mexicana [PDF]
Parasitology, 1998 Promastigotes of Leishmania braziliensis, L. donovani, L. major and L. mexicana recently derived from tissue amastigotes were cultured in Schneider's Drosophila medium supplemented with 20% (v/v) heat-inactivated foetal calf serum and 25 μg gentamicin sulfate/ml at pH 5·5.
Zakai, H A, Chance, M L, Bates, P A
openaire +2 more sources
Pharmaceuticals, 2022 Leishmaniasis may occur in three different clinical forms, namely, visceral, mucocutaneous and cutaneous, which are caused by different species of trypanosomatid protozoans of the genus Leishmania. Pentavalent antimonials are the leading treatment for cutaneous leishmaniasis despite the hepatic, renal, and cardiac toxicity. In addition, the response of
Sara M. Robledo +7 more
openaire +4 more sources
IL-1β induces MICA/B expression in L. braziliensis patients.
, 2023 RNAseq analysis from 7 healthy skin (HS) compared to lesions from 21 L. braziliensis-infected patients. (A) Gene expression of IL1B in HS and lesions from L. braziliensis-infected patients (CL). (B) Correlation between MICB expression and IL1B expression
Phillip Scott (268925) +9 more
core +1 more source