Results 21 to 30 of about 1,875,854 (282)

Molecular Backgrounds of ERAP1 Downregulation in Cervical Carcinoma

open access: yesAnalytical Cellular Pathology, 2015
The antigen processing machinery (APM) plays an important role in immune recognition of virally infected and transformed cells. Defective expression of the APM component ERAP1 is associated with progression and poor clinical outcome in cervical carcinoma.
Akash M. Mehta   +4 more
doaj   +1 more source

PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy [PDF]

open access: yes, 2017
Pancreatic ductal adenocarcinoma (PDAC) is considered a non‐immunogenic tumor, and immune checkpoint inhibitor monotherapy lacks efficacy in this disease. Radiotherapy (RT) can stimulate the immune system.
Azad, Abul   +11 more
core   +1 more source

Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors [PDF]

open access: yes, 2016
PURPOSE: Subsets of pituitary tumors exhibit an aggressive clinical courses and recur despite surgery, radiation, and chemotherapy. Because modulation of the immune response through inhibition of T-cell checkpoints has led to durable clinical responses ...
Agar, Nathalie Y. R.   +13 more
core   +3 more sources

Impact of Green Practices on Buying Habits in Pakistan’s Food Sector

open access: yesECONOMICS, 2019
The review intends to research the green advertising practices and its consequences for the client’s image inclination in sustenance segment of Pakistan.
Jafar Rana Adeel   +2 more
doaj   +1 more source

Efficient Minimization Methods of Mixed l2-l1 and l1-l1 Norms for Image Restoration [PDF]

open access: yesSIAM Journal on Scientific Computing, 2006
Image restoration problems are often solved by finding the minimizer of a suitable objective function. Usually this function consists of a data-fitting term and a regularization term. For the least squares solution, both the data-fitting and the regularization terms are in the $\ell$2 norm.
Ng, MK, Fu, HY, Nikolova, M, Barlow, JL
openaire   +3 more sources

ADAR1 restricts LINE-1 retrotransposition [PDF]

open access: yes, 2016
Adenosine deaminases acting on RNA (ADARs) are involved in RNA editing that converts adenosines to inosines in double-stranded RNAs. ADAR1 was demonstrated to be functional on different viruses exerting either antiviral or proviral effects.
Antonioni, Ambra   +9 more
core   +2 more sources

Investigating the Teachers’ Perceptions toward the Use of L1 in Teaching English

open access: yesIdeas, 2021
This study explores the teachers’ perceptions of using the first language (L1) when teaching English. The conceptual work of literature review is applied as the research method. This means previous works were analysed to investigate teachers’ perceptions
Dodi Widia Nanda
doaj   +1 more source

The Mediating Role of Knowledge Sharing on the Relationship Between Competitive Intelligence and Product Development: Evidence from Jordan

open access: yesFoundations of Management, 2022
The purpose of this study is to investigate the mediating role of knowledge sharing on the relationship between competitive intelligence and product development. A cross-sectional design was used in this study.
Abuzaid Ahmad Nasser
doaj   +1 more source

Optimization for L1-Norm Error Fitting via Data Aggregation [PDF]

open access: yes, 2019
We propose a data aggregation-based algorithm with monotonic convergence to a global optimum for a generalized version of the L1-norm error fitting model with an assumption of the fitting function.
Park, Young-Woong, Park, Young-Woong
core   +4 more sources

Normal Disfluency in Pre-schoolers: Silences, Pauses, and Repetitions [PDF]

open access: yesJournal of Language Horizons, 2017
Delving into the amazing and confounding language of four-, five-, or six-year olds, who dexterously and quite diligently use language for a myriad of purposes has always been intriguing to the pundits of first language acquisition.
Zohreh Nafissi, Anahid Ramezanee
doaj   +1 more source

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